Table of Contents

• K. L. Kompa
• and R. D. Levine

A molecular logic gate

• Jason C. Tanny
• and Danesh Moazed

Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product

• Tanya Jonassen,
• Pamela L. Larsen,
• and Catherine F. Clarke

A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants

• Tara Harmer,
• Martin Wu,
• and Robert Schleif

The role of rigidity in DNA looping-unlooping by AraC

• Ya-Jun Zheng,
• Zong-xiang Xia,
• Zhi-wei Chen,
• F. Scott Mathews,
• and Thomas C. Bruice

Catalytic mechanism of quinoprotein methanol dehydrogenase: A theoretical and x-ray crystallographic investigation

• Olivier Danot

A complex signaling module governs the activity of MalT, the prototype of an emerging transactivator family

• Yong Li
• and Sidney Altman

A subunit of human nuclear RNase P has ATPase activity

• Daniela Barillà,
• Barbara A. Lee,
• and Nick J. Proudfoot

Cleavage/polyadenylation factor IA associates with the carboxyl-terminal domain of RNA polymerase II in Saccharomyces cerevisiae

• Barbara S. Berlett,
• Rodney L. Levine,
• P. Boon Chock,
• Mordechai Chevion,
• and Earl R. Stadtman

Antioxidant activity of Ferrozine–iron–amino acid complexes

• R. G. Shulman
• and D. L. Rothman

The “glycogen shunt” in exercising muscle: A role for glycogen in muscle energetics and fatigue

• Daniel Yarbrough,
• Rebekka M. Wachter,
• Karen Kallio,
• Mikhail V. Matz,
• and S. James Remington

Refined crystal structure of DsRed, a red fluorescent protein from coral, at 2.0-Å resolution

• Andres F. Oberhauser,
• Paul K. Hansma,
• Mariano Carrion-Vazquez,
• and Julio M. Fernandez

Stepwise unfolding of titin under force-clamp atomic force microscopy

• Edouard I. Azzam,
• Sonia M. de Toledo,
• and John B. Little

Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from α-particle irradiated to nonirradiated cells

• Tapan Kanti Das,
• Manon Couture,
• Yannick Ouellet,
• Michel Guertin,
• and Denis L. Rousseau

Simultaneous observation of the O—O and Fe—O₂ stretching modes in oxyhemoglobins

• Fabrice Dumas,
• Myriam Duckely,
• Pawel Pelczar,
• Patrick Van Gelder,
• and Barbara Hohn

An Agrobacterium VirE2 channel for transferred-DNA transport into plant cells

• Teruo Hayashi
• and Tsung-Ping Su

Regulating ankyrin dynamics: Roles of sigma-1 receptors

• Cain H. Yam,
• Wai Yi Siu,
• Daniel Kaganovich,
• Joan V. Ruderman,
• and Randy Y. C. Poon

Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT

• Claire M. Steppan,
• Elizabeth J. Brown,
• Christopher M. Wright,
• Savitha Bhat,
• Ronadip R. Banerjee,
• Charlotte Y. Dai,
• Gregory H. Enders,
• Debra G. Silberg,
• Xiaoming Wen,
• Gary D. Wu,
• and Mitchell A. Lazar

A family of tissue-specific resistin-like molecules

• Bryan A. Laffitte,
• Joyce J. Repa,
• Sean B. Joseph,
• Damien C. Wilpitz,
• Heidi R. Kast,
• David J. Mangelsdorf,
• and Peter Tontonoz

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

• Michael F. Princiotta,
• Ulrich Schubert,
• Weisan Chen,
• Jack R. Bennink,
• Jayhyuk Myung,
• Craig M. Crews,
• and Jonathan W. Yewdell

Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival

• Thomas E. Meigs,
• Timothy A. Fields,
• David D. McKee,
• and Patrick J. Casey

Interaction of Gα12 and Gα13 with the cytoplasmic domain of cadherin provides a mechanism for β-catenin release

• Michelle M. Riehle,
• Albert F. Bennett,
• and Anthony D. Long

Genetic architecture of thermal adaptation in Escherichia coli

• Jing-Zhong Lin,
• Anthony H. D. Brown,
• and Michael T. Clegg

Heterogeneous geographic patterns of nucleotide sequence diversity between two alcohol dehydrogenase genes in wild barley (Hordeum vulgare subspecies spontaneum)

• Sanjay Jain
• and Sandeep Krishna

A model for the emergence of cooperation, interdependence, and structure in evolving networks

• Eric A. Gaucher,
• Michael M. Miyamoto,
• and Steven A. Benner

Function–structure analysis of proteins using covarion-based evolutionary approaches: Elongation factors

• Michele K. Anderson,
• Xiao Sun,
• Ann L. Miracle,
• Gary W. Litman,
• and Ellen V. Rothenberg

Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria

• Takashi Kuramoto,
• Kazuhiro Kitada,
• Toshihide Inui,
• Yoshifumi Sasaki,
• Kazumi Ito,
• Takao Hase,
• Saburo Kawagachi,
• Yoshihiro Ogawa,
• Kazuwa Nakao,
• Gregory S. Barsh,
• Minako Nagao,
• Toshikazu Ushijima,
• and Tadao Serikawa

Attractin/Mahogany/Zitter plays a critical role in myelination of the central nervous system

• Jir̆í Hejnar,
• Petra Hájková,
• Jir̆í Plachý,
• Daniel Elleder,
• Volodymyr Stepanets,
• and Jan Svoboda

CpG island protects Rous sarcoma virus-derived vectors integrated into nonpermissive cells from DNA methylation and transcriptional suppression

• Yuri M. Moshkin,
• Artyom A. Alekseyenko,
• Valery F. Semeshin,
• Anne Spierer,
• Pierre Spierer,
• Grigoryi F. Makarevich,
• Elena S. Belyaeva,
• and Igor F. Zhimulev

The Bithorax Complex of Drosophila melanogaster: Underreplication and morphology in polytene chromosomes

• Hidekazu Nishigori,
• Hideaki Tomura,
• Naoko Tonooka,
• Masao Kanamori,
• Shirou Yamada,
• Kimie Sho,
• Ituro Inoue,
• Nobuyuki Kikuchi,
• Kazumichi Onigata,
• Itaru Kojima,
• Tomoko Kohama,
• Kazuya Yamagata,
• Qin Yang,
• Yuji Matsuzawa,
• Takashi Miki,
• Susumu Seino,
• Mi-Young Kim,
• Hueng-Sik Choi,
• Yoon-Kwang Lee,
• David D. Moore,
• and Jun Takeda

Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects

• Kenneth H. Buetow,
• Michael Edmonson,
• Richard MacDonald,
• Robert Clifford,
• Ping Yip,
• Jenny Kelley,
• Daniel P. Little,
• Robert Strausberg,
• Hubert Koester,
• Charles R. Cantor,
• and Andreas Braun

High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

• John R. Kelsoe,
• M. Anne Spence,
• Erika Loetscher,
• Montserrat Foguet,
• A. Dessa Sadovnick,
• Ronald A. Remick,
• Pamela Flodman,
• Jason Khristich,
• Zofi Mroczkowski-Parker,
• John L. Brown,
• Diane Masser,
• Sharon Ungerleider,
• Mark H. Rapaport,
• William L. Wishart,
• and Hermann Luebbert

A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22

• Michele K. Anderson,
• Xiao Sun,
• Ann L. Miracle,
• Gary W. Litman,
• and Ellen V. Rothenberg

Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria

• Sharon A. Stranford,
• June C. Ong,
• Beatriz Martinez-Mariño,
• Michael Busch,
• Frederick M. Hecht,
• James Kahn,
• and Jay A. Levy

Reduction in CD8⁺ cell noncytotoxic anti-HIV activity in individuals receiving highly active antiretroviral therapy during primary infection

• Dominik Filipp,
• Kamel Alizadeh-Khiavi,
• Christopher Richardson,
• Anthony Palma,
• Nethnapha Paredes,
• Osamu Takeuchi,
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