Table of Contents

Commentaries

Commentary:
- Michael A. J. Ferguson
Glycosylphosphatidylinositol biosynthesis validated as a drug target for African sleeping sickness
PNAS 2000 97:10673-10675
- See companion article on page 10336 in issue 19 of volume 97
Commentary:
- Daniel H. Geschwind
Mice, microarrays, and the genetic diversity of the brain
PNAS 2000 97:10676-10678
- See companion article on page 11038 in issue 20 of volume 97
Commentary:
- Jefferson Foote
- and Herman N. Eisen
Breaking the affinity ceiling for antibodies and T cell receptors
PNAS 2000 97:10679-10681
- See companion article on page 5387 in issue 10 of volume 97
- See companion article on page 10701 in issue 20 of volume 97
Commentary:
- Charles Janeway, Jr.
- and Ruslan Medzhitov
Viral interference with IL-1 and Toll signaling
PNAS 2000 97:10682-10683
- See companion article on page 10520 in issue 19 of volume 97
- See companion article on page 10162 in issue 18 of volume 97
Commentary:
- David Pilbeam
Hominoid systematics: The soft evidence
PNAS 2000 97:10684-10686; published online before print September 19, 2000
- See companion article on page 11130 in issue 20 of volume 97

Physical Sciences

Applied Physical Sciences

Select this article
Physical Sciences - Applied Physical Sciences - Biological Sciences - Cell Biology:
- L. L. Sohn,
- O. A. Saleh,
- G. R. Facer,
- A. J. Beavis,
- R. S. Allan,
- and D. A. Notterman
Capacitance cytometry: Measuring biological cells one by one
PNAS 2000 97:10687-10690; published online before print September 19, 2000

Chemistry

Select this article
Physical Sciences - Chemistry - Biological Sciences - Microbiology:
- Alain Stintzi,
- Carmen Barnes,
- Jide Xu,
- and Kenneth N. Raymond
Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm
PNAS 2000 97:10691-10696; published online before print September 19, 2000

Physics

Select this article
Physical Sciences - Physics:
- J. P. Schiffer,
- M. Drewsen,
- J. S. Hangst,
- and L. Hornekær
From the Cover: Temperature, ordering, and equilibrium with time-dependent confining forces
PNAS 2000 97:10697-10700; published online before print September 19, 2000

Social Sciences

Anthropology

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Social Sciences - Anthropology:
- Sally Gibbs,
- Mark Collard,
- and Bernard Wood
From the Cover: Soft-tissue characters in higher primate phylogenetics
PNAS 2000 97:11130-11132; published online before print September 19, 2000
- See commentary article on page 10684 in issue 20 of volume 97

Biological Sciences

Applied Biological Sciences

Select this article
Biological Sciences - Applied Biological Sciences:
- Eric T. Boder,
- Katarina S. Midelfort,
- and K. Dane Wittrup
Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity
PNAS 2000 97:10701-10705; published online before print September 12, 2000
- See commentary article on page 10679 in issue 20 of volume 97

Biophysics

Select this article
Biological Sciences - Biophysics:
- Chinlin Guo,
- Herbert Levine,
- and David A. Kessler
How does a β-hairpin fold/unfold? Competition between topology and heterogeneity in a solvable model
PNAS 2000 97:10775-10779; published online before print September 19, 2000
Select this article
Biological Sciences - Biophysics:
- Philippe Ferrara
- and Amedeo Caflisch
Folding simulations of a three-stranded antiparallel β-sheet peptide
PNAS 2000 97:10780-10785; published online before print September 12, 2000
Select this article
Biological Sciences - Biophysics:
- Franc Avbelj,
- Peizhi Luo,
- and Robert L. Baldwin
Energetics of the interaction between water and the helical peptide group and its role in determining helix propensities
PNAS 2000 97:10786-10791; published online before print September 12, 2000
Select this article
Biological Sciences - Biophysics:
- Charbel Haber,
- Sami Alom Ruiz,
- and Denis Wirtz
Shape anisotropy of a single random-walk polymer
PNAS 2000 97:10792-10795; published online before print September 12, 2000
Select this article
Biological Sciences - Biophysics:
- Jiro Takei,
- Rui-Ai Chu,
- and Yawen Bai
Absence of stable intermediates on the folding pathway of barnase
PNAS 2000 97:10796-10801; published online before print September 12, 2000
Select this article
Biological Sciences - Biophysics:
- C. Gergely,
- J.-C. Voegel,
- P. Schaaf,
- B. Senger,
- M. Maaloum,
- J. K. H. Hörber,
- and J. Hemmerlé
Unbinding process of adsorbed proteins under external stress studied by atomic force microscopy spectroscopy
PNAS 2000 97:10802-10807; published online before print September 12, 2000
Select this article
Biological Sciences - Biophysics:
- Peter J. Walla,
- Patricia A. Linden,
- Chao-Ping Hsu,
- Gregory D. Scholes,
- and Graham R. Fleming
Femtosecond dynamics of the forbidden carotenoid S₁ state in light-harvesting complexes of purple bacteria observed after two-photon excitation
PNAS 2000 97:10808-10813; published online before print September 12, 2000

Cell Biology

Select this article
Physical Sciences - Applied Physical Sciences - Biological Sciences - Cell Biology:
- L. L. Sohn,
- O. A. Saleh,
- G. R. Facer,
- A. J. Beavis,
- R. S. Allan,
- and D. A. Notterman
Capacitance cytometry: Measuring biological cells one by one
PNAS 2000 97:10687-10690; published online before print September 19, 2000
Select this article
Biological Sciences - Cell Biology:
- Miki Shinohara,
- Stephen L. Gasior,
- Douglas K. Bishop,
- and Akira Shinohara
Tid1/Rdh54 promotes colocalization of Rad51 and Dmc1 during meiotic recombination
PNAS 2000 97:10814-10819
Select this article
Biological Sciences - Cell Biology:
- Marie Classon,
- Sofie Salama,
- Carolyn Gorka,
- Roseann Mulloy,
- Pascal Braun,
- and Ed Harlow
Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control
PNAS 2000 97:10820-10825; published online before print September 19, 2000
Select this article
Biological Sciences - Cell Biology:
- Marie Classon,
- Brian K. Kennedy,
- Roseann Mulloy,
- and Ed Harlow
Opposing roles of pRB and p107 in adipocyte differentiation
PNAS 2000 97:10826-10831; published online before print September 19, 2000
Select this article
Biological Sciences - Cell Biology:
- Saori Sato,
- Naoya Fujita,
- and Takashi Tsuruo
Modulation of Akt kinase activity by binding to Hsp90
PNAS 2000 97:10832-10837; published online before print September 19, 2000

Developmental Biology

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Biological Sciences - Developmental Biology:
- Dorota A. Bulik,
- Ge Wei,
- Hidenao Toyoda,
- Akiko Kinoshita-Toyoda,
- W. Ross Waldrip,
- Jeffrey D. Esko,
- Phillips W. Robbins,
- and Scott B. Selleck
sqv-3, -7, and -8, a set of genes affecting morphogenesis in Caenorhabditis elegans, encode enzymes required for glycosaminoglycan biosynthesis
PNAS 2000 97:10838-10843
Select this article
Biological Sciences - Developmental Biology:
- Michael Stauber,
- Heike Taubert,
- and Urs Schmidt-Ott
Function of bicoid and hunchback homologs in the basal cyclorrhaphan fly Megaselia (Phoridae)
PNAS 2000 97:10844-10849; published online before print September 19, 2000

Ecology

Select this article
Biological Sciences - Ecology:
- Joshua B. Plotkin,
- Matthew D. Potts,
- Douglas W. Yu,
- Sarayudh Bunyavejchewin,
- Richard Condit,
- Robin Foster,
- Stephen Hubbell,
- James LaFrankie,
- N. Manokaran,
- Lee Hua Seng,
- Raman Sukumar,
- Martin A. Nowak,
- and Peter S. Ashton
Predicting species diversity in tropical forests
PNAS 2000 97:10850-10854

Evolution

Select this article
Biological Sciences - Evolution:
- Roeland C. H. J. Van Ham,
- Fernando González-Candelas,
- Francisco J. Silva,
- Beatriz Sabater,
- Andrés Moya,
- and Amparo Latorre
Postsymbiotic plasmid acquisition and evolution of the repA1-replicon in Buchnera aphidicola
PNAS 2000 97:10855-10860; published online before print September 12, 2000
Select this article
Biological Sciences - Evolution:
- Paul S. Schmidt,
- David D. Duvernell,
- and Walter F. Eanes
Adaptive evolution of a candidate gene for aging in Drosophila
PNAS 2000 97:10861-10865; published online before print September 19, 2000
Select this article
Biological Sciences - Evolution:
- Masatoshi Nei,
- Igor B. Rogozin,
- and Helen Piontkivska
Purifying selection and birth-and-death evolution in the ubiquitin gene family
PNAS 2000 97:10866-10871

Genetics

Select this article
Biological Sciences - Genetics:
- Yurij Ionov,
- Hiroyuki Yamamoto,
- Stanislaw Krajewski,
- John C. Reed,
- and Manuel Perucho
Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution
PNAS 2000 97:10872-10877; published online before print September 12, 2000
Select this article
Biological Sciences - Genetics:
- I. G. Sharina,
- J. S. Krumenacker,
- E. Martin,
- and F. Murad
Genomic organization of α1 and β1 subunits of the mammalian soluble guanylyl cyclase genes
PNAS 2000 97:10878-10883; published online before print September 12, 2000
Select this article
Biological Sciences - Genetics:
- Hiroshi Kadokura,
- Martin Bader,
- Hongping Tian,
- James C. A. Bardwell,
- and Jon Beckwith
Roles of a conserved arginine residue of DsbB in linking protein disulfide-bond-formation pathway to the respiratory chain of Escherichia coli
PNAS 2000 97:10884-10889
Select this article
Biological Sciences - Genetics:
- David K. Peyton,
- Tennore Ramesh,
- and Brett T. Spear
Position-dependent activity of α-fetoprotein enhancer element III in the adult liver is due to negative regulation
PNAS 2000 97:10890-10894; published online before print September 19, 2000
Select this article
Biological Sciences - Genetics:
- Luciano A. Moreira,
- Marten J. Edwards,
- Faisal Adhami,
- Nijole Jasinskiene,
- Anthony A. James,
- and Marcelo Jacobs-Lorena
Robust gut-specific gene expression in transgenic Aedes aegypti mosquitoes
PNAS 2000 97:10895-10898
Select this article
Biological Sciences - Genetics:
- Mohammed Abdul Motaleb,
- Linda Corum,
- James L. Bono,
- Abdallah F. Elias,
- Patricia Rosa,
- D. Scott Samuels,
- and Nyles W. Charon
Borrelia burgdorferi periplasmic flagella have both skeletal and motility functions
PNAS 2000 97:10899-10904; published online before print September 19, 2000

FROM THE COVER

Glycosylphosphatidylinositol biosynthesis validated as a drug target for African sleeping sickness

Mice, microarrays, and the genetic diversity of the brain

Breaking the affinity ceiling for antibodies and T cell receptors

Viral interference with IL-1 and Toll signaling

Hominoid systematics: The soft evidence

Capacitance cytometry: Measuring biological cells one by one

Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm

From the Cover: Temperature, ordering, and equilibrium with time-dependent confining forces

From the Cover: Soft-tissue characters in higher primate phylogenetics

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity

Elucidating the mechanism of familial amyloidosis– Finnish type: NMR studies of human gelsolin domain 2

Molecular mechanisms underlying differential odor responses of a mouse olfactory receptor

Quantitative, chemically specific imaging of selenium transformation in plants

Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: Structure-based mechanism of conversion

Unraveling the mechanism of the lactose permease of Escherichia coli

Old Yellow Enzyme: Stepwise reduction of nitro-olefins and catalysis of aci-nitro tautomerization

Position-specific trapping of topoisomerase I–DNA cleavage complexes by intercalated benzo[a]- pyrene diol epoxide adducts at the 6-amino group of adenine

An initiation element in the yeast CUP1 promoter is recognized by RNA polymerase II in the absence of TATA box-binding protein if the DNA is negatively supercoiled

Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts

N-terminal transcriptional activation domain of LZIP comprises two LxxLL motifs and the Host Cell Factor-1 binding motif

Human recombinant soluble guanylyl cyclase: Expression, purification, and regulation

CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR)

How does a β-hairpin fold/unfold? Competition between topology and heterogeneity in a solvable model

Folding simulations of a three-stranded antiparallel β-sheet peptide

Energetics of the interaction between water and the helical peptide group and its role in determining helix propensities

Shape anisotropy of a single random-walk polymer

Absence of stable intermediates on the folding pathway of barnase

Unbinding process of adsorbed proteins under external stress studied by atomic force microscopy spectroscopy

Femtosecond dynamics of the forbidden carotenoid S1 state in light-harvesting complexes of purple bacteria observed after two-photon excitation

Capacitance cytometry: Measuring biological cells one by one

Tid1/Rdh54 promotes colocalization of Rad51 and Dmc1 during meiotic recombination

Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control

Opposing roles of pRB and p107 in adipocyte differentiation

Modulation of Akt kinase activity by binding to Hsp90

sqv-3, -7, and -8, a set of genes affecting morphogenesis in Caenorhabditis elegans, encode enzymes required for glycosaminoglycan biosynthesis

Function of bicoid and hunchback homologs in the basal cyclorrhaphan fly Megaselia (Phoridae)

Predicting species diversity in tropical forests

Postsymbiotic plasmid acquisition and evolution of the repA1-replicon in Buchnera aphidicola

Adaptive evolution of a candidate gene for aging in Drosophila

Purifying selection and birth-and-death evolution in the ubiquitin gene family

Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution

Genomic organization of α1 and β1 subunits of the mammalian soluble guanylyl cyclase genes

Roles of a conserved arginine residue of DsbB in linking protein disulfide-bond-formation pathway to the respiratory chain of Escherichia coli

Position-dependent activity of α-fetoprotein enhancer element III in the adult liver is due to negative regulation

Robust gut-specific gene expression in transgenic Aedes aegypti mosquitoes

Borrelia burgdorferi periplasmic flagella have both skeletal and motility functions

Femtosecond dynamics of the forbidden carotenoid S₁ state in light-harvesting complexes of purple bacteria observed after two-photon excitation