Table of Contents

• Glaucia R. Martinez,
• Paolo Di Mascio,
• Marcelo G. Bonini,
• Ohara Augusto,
• Karlis Briviba,
• Helmut Sies,
• Patrick Maurer,
• Ursula Röthlisberger,
• Susanna Herold,
• and Willem H. Koppenol

Peroxynitrite does not decompose to singlet oxygen ( 1 Δ g O 2 ) and nitroxyl (NO − )

• David M. Horn,
• Roman A. Zubarev,
• and Fred W. McLafferty

Automated de novo sequencing of proteins by tandem high-resolution mass spectrometry

• Nadav M. Shnerb,
• Yoram Louzoun,
• Eldad Bettelheim,
• and Sorin Solomon

The importance of being discrete: Life always wins on the surface

• O. Oms,
• J. M. Parés,
• B. Martínez-Navarro,
• J. Agustí,
• I. Toro,
• G. Martínez-Fernández,
• and A. Turq

Early human occupation of Western Europe: Paleomagnetic dates for two paleolithic sites in Spain

• Ingrid M. Pruimboom-Brees,
• Tim W. Morgan,
• Mark R. Ackermann,
• Evelyn D. Nystrom,
• James E. Samuel,
• Nancy A. Cornick,
• and Harley W. Moon

Cattle lack vascular receptors for Escherichia coli O157:H7 Shiga toxins

• Glaucia R. Martinez,
• Paolo Di Mascio,
• Marcelo G. Bonini,
• Ohara Augusto,
• Karlis Briviba,
• Helmut Sies,
• Patrick Maurer,
• Ursula Röthlisberger,
• Susanna Herold,
• and Willem H. Koppenol

Peroxynitrite does not decompose to singlet oxygen ( 1 Δ g O 2 ) and nitroxyl (NO − )

• Michael Downes,
• Peter Ordentlich,
• Hung-Ying Kao,
• Jacqueline G. A. Alvarez,
• and Ronald M. Evans

Identification of a nuclear domain with deacetylase activity

• Kisaburo Nagamune,
• Tomoyoshi Nozaki,
• Yusuke Maeda,
• Kazuhito Ohishi,
• Toshihide Fukuma,
• Tatsuru Hara,
• Ralph T. Schwarz,
• Christine Sütterlin,
• Reto Brun,
• Howard Riezman,
• and Taroh Kinoshita

Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

• Géraldine Carrard,
• Anu Koivula,
• Hans Söderlund,
• and Pierre Béguin

Cellulose-binding domains promote hydrolysis of different sites on crystalline cellulose

• Lena Burri,
• Jörg Höckendorff,
• Ulrich Boehm,
• Thorsten Klamp,
• R. Jürgen Dohmen,
• and Frédéric Lévy

Identification and characterization of a mammalian protein interacting with 20S proteasome precursors

• Jonathan A. Lukin,
• Virgil Simplaceanu,
• Ming Zou,
• Nancy T. Ho,
• and Chien Ho

NMR reveals hydrogen bonds between oxygen and distal histidines in oxyhemoglobin

• Zachary Shriver,
• Mallikarjun Sundaram,
• Ganesh Venkataraman,
• Jawed Fareed,
• Robert Linhardt,
• Klaus Biemann,
• and Ram Sasisekharan

Cleavage of the antithrombin III binding site in heparin by heparinases and its implication in the generation of low molecular weight heparin

• Elissa L. Ash,
• James L. Sudmeier,
• Regina M. Day,
• Matthew Vincent,
• Ekaterina V. Torchilin,
• Kristin Coffman Haddad,
• Elizabeth M. Bradshaw,
• David G. Sanford,
• and William W. Bachovchin

Unusual 1 H NMR chemical shifts support (His) C ɛ 1 —H⋅⋅⋅O⩵C H-bond: Proposal for reaction-driven ring flip mechanism in serine protease catalysis

• Katrin G. Heinze,
• Andre Koltermann,
• and Petra Schwille

Simultaneous two-photon excitation of distinct labels for dual-color fluorescence crosscorrelation analysis

• Brian Kuhlman
• and David Baker

Native protein sequences are close to optimal for their structures

• Shuhei Matsuoka,
• Galit Rotman,
• Akira Ogawa,
• Yosef Shiloh,
• Katsuyuki Tamai,
• and Stephen J. Elledge

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

• Chao-Zhou Ni,
• Kate Welsh,
• Eugen Leo,
• Chu-kuan Chiou,
• Hao Wu,
• John C. Reed,
• and Kathryn R. Ely

Molecular basis for CD40 signaling mediated by TRAF3

• Lelio Orci,
• Mariella Ravazzola,
• Allen Volchuk,
• Thomas Engel,
• Michael Gmachl,
• Mylène Amherdt,
• Alain Perrelet,
• Thomas H. Söllner,
• and James E. Rothman

Anterograde flow of cargo across the Golgi stack potentially mediated via bidirectional “percolating” COPI vesicles

• Ben-Kuen Chen
• and Wen-Chang Chang

Functional interaction between c-Jun and promoter factor Sp1 in epidermal growth factor-induced gene expression of human 12( S )-lipoxygenase

• Nargis Nasrin,
• Scott Ogg,
• Catherine M. Cahill,
• William Biggs,
• Simin Nui,
• Justin Dore,
• Dominica Calvo,
• Yang Shi,
• Gary Ruvkun,
• and Maria C. Alexander-Bridges

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells

• Andreas Begitt,
• Thomas Meyer,
• Marleen van Rossum,
• and Uwe Vinkemeier

Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain

• James M. Angelastro,
• Lars Klimaschewski,
• Song Tang,
• Ottavio V. Vitolo,
• Tamily A. Weissman,
• Laura T. Donlin,
• Michael L. Shelanski,
• and Lloyd A. Greene

Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling

• Takumi Kamura,
• Shigeo Sato,
• Kazuhiro Iwai,
• Maria Czyzyk-Krzeska,
• Ronald C. Conaway,
• and Joan Weliky Conaway

Activation of HIF1α ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

• Adrian W. Moore,
• Sandra Barbel,
• Lily Yeh Jan,
• and Yuh Nung Jan

A genomewide survey of basic helix–loop–helix factors in Drosophila

• Garet P. Lahvis,
• Susanne L. Lindell,
• Russell S. Thomas,
• Robert S. McCuskey,
• Christopher Murphy,
• Edward Glover,
• Michael Bentz,
• James Southard,
• and Christopher A. Bradfield

Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice

• Eirikur Palsson
• and Hans G. Othmer

A model for individual and collective cell movement in Dictyostelium discoideum

• John S. Mudgett,
• Jixiang Ding,
• Lucia Guh-Siesel,
• Nicole A. Chartrain,
• Lu Yang,
• Shobhna Gopal,
• and Michael M. Shen

Essential role for p38α mitogen-activated protein kinase in placental angiogenesis

• Olivier Tenaillon,
• Hervé Le Nagard,
• Bernard Godelle,
• and François Taddei

Mutators and sex in bacteria: Conflict between adaptive strategies

• David F. LePage,
• Deanna M. Church,
• Elise Millie,
• Terry J. Hassold,
• and Ronald A. Conlon

Rapid generation of nested chromosomal deletions on mouse chromosome 2

• Sandra T. Merino,
• W. Jason Cummings,
• Sonia N. Acharya,
• and Miriam E. Zolan

Replication-dependent early meiotic requirement for Spo11 and Rad50

• Connie M. Drysdale,
• Dennis W. McGraw,
• Catharine B. Stack,
• J. Claiborne Stephens,
• Richard S. Judson,
• Krishnan Nandabalan,
• Kevin Arnold,
• Gualberto Ruano,
• and Stephen B. Liggett

Complex promoter and coding region β 2 -adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

• Xiaoxia Li,
• Mairead Commane,
• Huiqin Nie,
• Xianxin Hua,
• Moitreyee Chatterjee-Kishore,
• David Wald,
• Michael Haag,
• and George R. Stark

Act1, an NF-κB-activating protein

• Antonio Leonardi,
• Alain Chariot,
• Estefania Claudio,
• Kirk Cunningham,
• and Ulrich Siebenlist

CIKS, a connection to IκB kinase and stress-activated protein kinase

• K. Yamazaki,
• G. K. Beauchamp,
• M. Curran,
• J. Bard,
• and E. A. Boyse

Parent–progeny recognition as a function of MHC odortype identity

• Davy A. P. Rockx,
• Rebecca Mason,
• Anneke van Hoffen,
• Michelle Craig Barton,
• Elisabetta Citterio,
• David B. Bregman,
• Albert A. van Zeeland,
• Harry Vrieling,
• and Leon H. F. Mullenders

UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II

• Hiroshi Ochi,
• Nidia H. De Jesus,
• Fred H. Hsieh,
• K. Frank Austen,
• and Joshua A. Boyce

IL-4 and -5 prime human mast cells for different profiles of IgE-dependent cytokine production

• Shiho Tsujino,
• James P. Di Santo,
• Akinori Takaoka,
• Teresa L. McKernan,
• Shigeru Noguchi,
• Choji Taya,
• Hiromichi Yonekawa,
• Takashi Saito,
• Tadatsugu Taniguchi,
• and Hodaka Fujii