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Proceedings of the National Academy of Sciences of the United States of America
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Table of Contents
May 9, 2000; 97 (10)
Index By Author
Cover Photo
FROM THE COVER
Dementia and neuronal microcolumn disruption
Staphylococcus surface proteins and pathogenesis
Supramolecular complexes in photosynthetic bacteria
Gene therapy for hemoglobin disorders
Cloning large viral RNA genomes as infectious BACs
Commentaries
Commentary
:
Pascale Cossart
and
Renaud Jonquières
Sortase, a universal target for therapeutic agents against Gram-positive bacteria?
PNAS
2000
97
:
5013
-
5015
Extract
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See companion article on page
5510
in issue 10 of volume 97
Commentary
:
Paul A. Loach
Supramolecular complexes in photosynthetic bacteria
PNAS
2000
97
:
5016
-
5018
Extract
Full Text
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Figures Only
See companion article on page
5197
in issue 10 of volume 97
Commentary
:
Edward G. Jones
Microcolumns in the cerebral cortex
PNAS
2000
97
:
5019
-
5021
Extract
Full Text
Full Text (PDF)
Figures Only
See companion article on page
5039
in issue 10 of volume 97
Commentary
:
Derek A. Persons
and
Arthur W. Nienhuis
Gene therapy for the hemoglobin disorders: Past, present, and future
PNAS
2000
97
:
5022
-
5024
Extract
Full Text
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See companion article on page
5411
in issue 10 of volume 97
Commentary
:
Michael M. C. Lai
The making of infectious viral RNA: No size limit in sight
PNAS
2000
97
:
5025
-
5027
Extract
Full Text
Full Text (PDF)
See companion article on page
5516
in issue 10 of volume 97
Commentary
:
Jean van Heijenoort
and
Laurent Gutmann
Correlation between the structure of the bacterial peptidoglycan monomer unit, the specificity of transpeptidation, and susceptibility to β-lactams
PNAS
2000
97
:
5028
-
5030
Extract
Full Text
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See companion article on page
4891
in issue 9 of volume 97
Commentary
:
Douglas A. Lauffenburger
Cell signaling pathways as control modules: Complexity for simplicity?
PNAS
2000
97
:
5031
-
5033
Extract
Full Text
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See companion article on page
4649
in issue 9 of volume 97
Perspective
Perspective - Perspective
:
Wolfgang K. H. Panofsky
National security and scientific communication
PNAS
2000
97
:
5034
-
5036
;
published ahead of print
April 25, 2000
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From the Academy
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From the Academy
:
From the Academy: New Members and Foreign Associates Elected to the National Academy of Sciences on May 2, 2000
PNAS
2000
97
:
5037
-
5038
;
published ahead of print
May 2, 2000
Abstract
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Physical Sciences
Applied Physical Sciences
Select this article
Physical Sciences - Applied Physical Sciences
:
S. V. Buldyrev
,
L. Cruz
,
T. Gomez-Isla
,
E. Gomez-Tortosa
,
S. Havlin
,
R. Le
,
H. E. Stanley
,
B. Urbanc
,
and
B. T. Hyman
From the Cover: Description of microcolumnar ensembles in association cortex and their disruption in Alzheimer and Lewy body dementias
PNAS
2000
97
:
5039
-
5043
;
published ahead of print
April 18, 2000
Abstract
Full Text
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See commentary article on page
5019
in issue 10 of volume 97
Chemistry
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Physical Sciences - Chemistry
:
Dale L. Boger
,
Haruhiko Sato
,
Aaron E. Lerner
,
Michael P. Hedrick
,
Robert A. Fecik
,
Hiroshi Miyauchi
,
Gordon D. Wilkie
,
Bryce J. Austin
,
Matthew P. Patricelli
,
and
Benjamin F. Cravatt
Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide
PNAS
2000
97
:
5044
-
5049
Abstract
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Physical Sciences - Chemistry - Biological Sciences - Biochemistry
:
David K. Leung
,
Zhiwei Yang
,
and
Ronald Breslow
Selective disruption of protein aggregation by cyclodextrin dimers
PNAS
2000
97
:
5050
-
5053
Abstract
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Engineering
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Physical Sciences - Engineering - Biological Sciences - Applied Biological Sciences
:
Anton P. J. Middelberg
,
Clay J. Radke
,
and
Harvey W. Blanch
Peptide interfacial adsorption is kinetically limited by the thermodynamic stability of self association
PNAS
2000
97
:
5054
-
5059
;
published ahead of print
May 2, 2000
Abstract
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Physics
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Physical Sciences - Physics
:
M. Jaletzky
and
F. H. Busse
New patterns of centrifugally driven thermal convection
PNAS
2000
97
:
5060
-
5064
Abstract
Full Text (PDF)
Social Sciences
Economic Sciences
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Social Sciences - Economic Sciences
:
E. Minelli
and
H. M. Polemarchakis
Nas–Walras equilibria of a large economy
PNAS
2000
97
:
5675
-
5678
Abstract
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Biological Sciences
Agricultural Sciences
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Biological Sciences - Agricultural Sciences
:
Maria P. Oria
,
Bruce R. Hamaker
,
John D. Axtell
,
and
Chia-Ping Huang
A highly digestible sorghum mutant cultivar exhibits a unique folded structure of endosperm protein bodies
PNAS
2000
97
:
5065
-
5070
;
published ahead of print
May 2, 2000
Abstract
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Applied Biological Sciences
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Physical Sciences - Engineering - Biological Sciences - Applied Biological Sciences
:
Anton P. J. Middelberg
,
Clay J. Radke
,
and
Harvey W. Blanch
Peptide interfacial adsorption is kinetically limited by the thermodynamic stability of self association
PNAS
2000
97
:
5054
-
5059
;
published ahead of print
May 2, 2000
Abstract
Full Text
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Biological Sciences - Applied Biological Sciences
:
J. Lyons
,
A. Rauh-Pfeiffer
,
Y. M. Yu
,
X.-M. Lu
,
D. Zurakowski
,
R. G. Tompkins
,
A. M. Ajami
,
V. R. Young
,
and
L. Castillo
Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet
PNAS
2000
97
:
5071
-
5076
;
published ahead of print
May 2, 2000
Abstract
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Biochemistry
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Physical Sciences - Chemistry - Biological Sciences - Biochemistry
:
David K. Leung
,
Zhiwei Yang
,
and
Ronald Breslow
Selective disruption of protein aggregation by cyclodextrin dimers
PNAS
2000
97
:
5050
-
5053
Abstract
Full Text
Full Text (PDF)
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Biological Sciences - Biochemistry
:
James A. Endrizzi
,
Peter T. Beernink
,
Tom Alber
,
and
H. K. Schachman
Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: Implications for allosteric regulation
PNAS
2000
97
:
5077
-
5082
;
published ahead of print
April 18, 2000
Abstract
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Biological Sciences - Biochemistry
:
Sudip S. Parikh
,
Gunter Walcher
,
Garry D. Jones
,
Geir Slupphaug
,
Hans E. Krokan
,
G. Michael Blackburn
,
and
John A. Tainer
Uracil-DNA glycosylase–DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
PNAS
2000
97
:
5083
-
5088
Abstract
Full Text
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Biological Sciences - Biochemistry
:
Lily Q. Dong
,
Luis R. Landa
,
Michael J. Wick
,
Li Zhu
,
Hideyuki Mukai
,
Yoshitaka Ono
,
and
Feng Liu
Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton
PNAS
2000
97
:
5089
-
5094
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Biochemistry
:
Premal H. Patel
and
Lawrence A. Loeb
DNA polymerase active site is highly mutable: Evolutionary consequences
PNAS
2000
97
:
5095
-
5100
Abstract
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Biological Sciences - Biochemistry
:
Zheng-Zheng Shi
,
Joseph Osei-Frimpong
,
Geeta Kala
,
Subbarao V. Kala
,
Roberto J. Barrios
,
Geetha M. Habib
,
Dana J. Lukin
,
Christopher M. Danney
,
Martin M. Matzuk
,
and
Michael W. Lieberman
Glutathione synthesis is essential for mouse development but not for cell growth in culture
PNAS
2000
97
:
5101
-
5106
Abstract
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Biological Sciences - Biochemistry
:
Li-Wei Hung
,
Elizabeth L. Holbrook
,
and
Stephen R. Holbrook
The crystal structure of the Rev binding element of HIV-1 reveals novel base pairing and conformational variability
PNAS
2000
97
:
5107
-
5112
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Biochemistry
:
Stefan Sperl
,
Uwe Jacob
,
Nuria Arroyo de Prada
,
Jörg Stürzebecher
,
Olaf G. Wilhelm
,
Wolfram Bode
,
Viktor Magdolen
,
Robert Huber
,
and
Luis Moroder
(4-Aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase
PNAS
2000
97
:
5113
-
5118
Abstract
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Biological Sciences - Biochemistry
:
Tyzoon K. Nomanbhoy
and
Paul R. Schimmel
Misactivated amino acids translocate at similar rates across surface of a tRNA synthetase
PNAS
2000
97
:
5119
-
5122
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Biochemistry
:
Jin Ye
,
Utpal P. Davé
,
Nick V. Grishin
,
Joseph L. Goldstein
,
and
Michael S. Brown
Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease
PNAS
2000
97
:
5123
-
5128
Abstract
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Biological Sciences - Biochemistry
:
M. von Bergen
,
P. Friedhoff
,
J. Biernat
,
J. Heberle
,
E.-M. Mandelkow
,
and
E. Mandelkow
Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif ( 306 VQIVYK 311 ) forming β structure
PNAS
2000
97
:
5129
-
5134
Abstract
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Biological Sciences - Biochemistry
:
Bing Zhu
,
Yong Zheng
,
Daniel Hess
,
Herbert Angliker
,
Steffen Schwarz
,
Michel Siegmann
,
Stéphane Thiry
,
and
Jean-Pierre Jost
5-Methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex
PNAS
2000
97
:
5135
-
5139
;
published ahead of print
April 25, 2000
Abstract
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Biological Sciences - Biochemistry
:
Yu Li
,
Michael L. Love
,
John A. Putkey
,
and
Carolyn Cohen
Bepridil opens the regulatory N-terminal lobe of cardiac troponin C
PNAS
2000
97
:
5140
-
5145
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Biochemistry
:
Huangen Ding
and
Bruce Demple
Direct nitric oxide signal transduction via nitrosylation of iron-sulfur centers in the SoxR transcription activator
PNAS
2000
97
:
5146
-
5150
Abstract
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Biological Sciences - Biochemistry
:
Glenn Walter
,
Elisabeth R. Barton
,
and
H. Lee Sweeney
Noninvasive measurement of gene expression in skeletal muscle
PNAS
2000
97
:
5151
-
5155
Abstract
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Biological Sciences - Biochemistry
:
Esther J. Tomlinson
and
Stuart J. Ferguson
Conversion of a c type cytochrome to a b type that spontaneously forms in vitro from apo protein and heme: Implications for c type cytochrome biogenesis and folding
PNAS
2000
97
:
5156
-
5160
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Biochemistry
:
Elon Portugaly
and
Michal Linial
Estimating the probability for a protein to have a new fold: A statistical computational model
PNAS
2000
97
:
5161
-
5166
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Biochemistry
:
Suzanne Gaudet
,
Daniel Branton
,
and
Robert A. Lue
Characterization of PDZ-binding kinase, a mitotic kinase
PNAS
2000
97
:
5167
-
5172
;
published ahead of print
April 25, 2000
Abstract
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Biological Sciences - Biochemistry
:
James Anderson
,
Lon Phan
,
and
Alan G. Hinnebusch
The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae
PNAS
2000
97
:
5173
-
5178
;
published ahead of print
April 25, 2000
Abstract
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Biophysics
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Biological Sciences - Biophysics
:
Ashok A. Deniz
,
Ted A. Laurence
,
Gangamani S. Beligere
,
Maxime Dahan
,
Andrew B. Martin
,
Daniel S. Chemla
,
Philip E. Dawson
,
Peter G. Schultz
,
and
Shimon Weiss
Single-molecule protein folding: Diffusion fluorescence resonance energy transfer studies of the denaturation of chymotrypsin inhibitor 2
PNAS
2000
97
:
5179
-
5184
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Biophysics
:
Adam A. Rostom
,
Paola Fucini
,
Dennis R. Benjamin
,
Ralf Juenemann
,
Knud H. Nierhaus
,
F. Ulrich Hartl
,
Christopher M. Dobson
,
and
Carol V. Robinson
Detection and selective dissociation of intact ribosomes in a mass spectrometer
PNAS
2000
97
:
5185
-
5190
Abstract
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Biological Sciences - Biophysics
:
Andreas Ulrich
,
Arndt A. P. Schmitz
,
Thomas Braun
,
Tao Yuan
,
Hans J. Vogel
,
and
Guy Vergères
Mapping the interface between calmodulin and MARCKS-related protein by fluorescence spectroscopy
PNAS
2000
97
:
5191
-
5196
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Biophysics
:
Raoul N. Frese
,
John D. Olsen
,
Rikard Branvall
,
Willem H. J. Westerhuis
,
C. Neil Hunter
,
and
Rienk van Grondelle
From the Cover: The long-range supraorganization of the bacterial photosynthetic unit: A key role for PufX
PNAS
2000
97
:
5197
-
5202
;
published ahead of print
May 2, 2000
Abstract
Full Text
Full Text (PDF)
Figures Only
See commentary article on page
5016
in issue 10 of volume 97
Select this article
Biological Sciences - Biophysics
:
George H. Patterson
,
Susan M. Knobel
,
Per Arkhammar
,
Ole Thastrup
,
and
David W. Piston
Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD(P)H responses in pancreatic islet β cells
PNAS
2000
97
:
5203
-
5207
;
published ahead of print
May 2, 2000
Abstract
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Cell Biology
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Biological Sciences - Cell Biology
:
Toru Ouchi
,
Sam W. Lee
,
Mutsuko Ouchi
,
Stuart A. Aaronson
,
and
Curt M. Horvath
Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes
PNAS
2000
97
:
5208
-
5213
;
published ahead of print
May 2, 2000
Abstract
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Biological Sciences - Cell Biology
:
Victor Yankiwski
,
Robert A. Marciniak
,
Leonard Guarente
,
and
Norma F. Neff
Nuclear structure in normal and Bloom syndrome cells
PNAS
2000
97
:
5214
-
5219
;
published ahead of print
April 25, 2000
Abstract
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Biological Sciences - Cell Biology
:
Toshi Shioda
,
Stephanie Andriole
,
Tetsuro Yahata
,
and
Kurt J. Isselbacher
A green fluorescent protein-reporter mammalian two-hybrid system with extrachromosomal maintenance of a prey expression plasmid: Application to interaction screening
PNAS
2000
97
:
5220
-
5224
Abstract
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Biological Sciences - Cell Biology
:
Chang Y. Chung
,
Susan Lee
,
Celia Briscoe
,
Charlene Ellsworth
,
and
Richard A. Firtel
Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells
PNAS
2000
97
:
5225
-
5230
Abstract
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Biological Sciences - Cell Biology
:
Jeffrey R. Huth
,
Edward T. Olejniczak
,
Renaldo Mendoza
,
Heng Liang
,
Edith A. S. Harris
,
Mark L. Lupher, Jr.
,
Amy E. Wilson
,
Stephen W. Fesik
,
and
Donald E. Staunton
NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding
PNAS
2000
97
:
5231
-
5236
Abstract
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Biological Sciences - Cell Biology
:
Bernard H. Ramsahoye
,
Detlev Biniszkiewicz
,
Frank Lyko
,
Victoria Clark
,
Adrian P. Bird
,
and
Rudolf Jaenisch
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
PNAS
2000
97
:
5237
-