Table of Contents

Commentaries

Commentary:
- Anthony Trewavas
How plants learn
PNAS 1999 96:4216-4218
- See companion article on page 4718 in issue 8 of volume 96
Commentary:
- A. W. Castleman, Jr.,
- Q. Zhong,
- and S. M. Hurley
Femtochemistry uncovers the nature of electron transfer reactions
PNAS 1999 96:4219-4220
- See companion article on page 2602 in issue 6 of volume 96
Commentary:
- Jacqueline A. Lees
- and Robert A. Weinberg
Tossing monkey wrenches into the clock: New ways of treating cancer
PNAS 1999 96:4221-4223
- See companion article on page 4325 in issue 8 of volume 96

Perspectives

Select this article
Perspective - Perspective:
- Robert P. Kirshner
Supernovae, an accelerating universe and the cosmological constant
PNAS 1999 96:4224-4227
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Perspective - Perspective:
- August E. Evrard
Real or virtual large-scale structure?
PNAS 1999 96:4228-4231
Select this article
Perspective - Perspective:
- Charles C. Steidel
Observing the epoch of galaxy formation
PNAS 1999 96:4232-4235
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Perspective - Perspective:
- Steven T. Myers
Scaling the universe: Gravitational lenses and the Hubble constant
PNAS 1999 96:4236-4239

Editorial

Editorial:
- The Editorial Board
PNAS Policy on Prior Publication
PNAS 1999 96:4215

Review

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Review:
- Lewis C. Cantley
- and Benjamin G. Neel
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
PNAS 1999 96:4240-4245

Physical Sciences

Chemistry

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Physical Sciences - Chemistry:
- Katrin Gessler,
- Isabel Usón,
- Takeshi Takaha,
- Norbert Krauss,
- Steven M. Smith,
- Shigetaka Okada,
- George M. Sheldrick,
- and Wolfram Saenger
V-Amylose at atomic resolution: X-ray structure of a cycloamylose with 26 glucose residues (cyclomaltohexaicosaose)
PNAS 1999 96:4246-4251
Select this article
Physical Sciences - Chemistry:
- Andrea Szabó-Nagy
- and Lajos Keszthelyi
Demonstration of the parity-violating energy difference between enantiomers
PNAS 1999 96:4252-4255
Select this article
Physical Sciences - Chemistry:
- Iwao Ojima,
- Subrata Chakravarty,
- Tadashi Inoue,
- Songnian Lin,
- Lifeng He,
- Susan Band Horwitz,
- Scott D. Kuduk,
- and Samuel J. Danishefsky
A common pharmacophore for cytotoxic natural products that stabilize microtubules
PNAS 1999 96:4256-4261
Select this article
Physical Sciences - Chemistry - Biological Sciences - Genetics:
- Wu Suen,
- Thomas G. Spiro,
- Lawrence C. Sowers,
- and Jacques R. Fresco
Identification by UV resonance Raman spectroscopy of an imino tautomer of 5-hydroxy-2′-deoxycytidine, a powerful base analog transition mutagen with a much higher unfavored tautomer frequency than that of the natural residue 2′-deoxycytidine
PNAS 1999 96:4500-4505

Physics

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Physical Sciences - Physics - Biological Sciences - Ecology:
- Eric Bonabeau,
- Laurent Dagorn,
- and Pierre Fréon
Scaling in animal group-size distributions
PNAS 1999 96:4472-4477

Social Sciences

Economic Sciences

Select this article
Social Sciences - Economic Sciences:
- James J. Heckman
- and Edward J. Vytlacil
Local instrumental variables and latent variable models for identifying and bounding treatment effects
PNAS 1999 96:4730-4734
- See commentary article on page 6575 in issue 12 of volume 96

How plants learn

Femtochemistry uncovers the nature of electron transfer reactions

Tossing monkey wrenches into the clock: New ways of treating cancer

Supernovae, an accelerating universe and the cosmological constant

Real or virtual large-scale structure?

Observing the epoch of galaxy formation

Scaling the universe: Gravitational lenses and the Hubble constant

PNAS Policy on Prior Publication

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

V-Amylose at atomic resolution: X-ray structure of a cycloamylose with 26 glucose residues (cyclomaltohexaicosaose)

Demonstration of the parity-violating energy difference between enantiomers

A common pharmacophore for cytotoxic natural products that stabilize microtubules

Identification by UV resonance Raman spectroscopy of an imino tautomer of 5-hydroxy-2′-deoxycytidine, a powerful base analog transition mutagen with a much higher unfavored tautomer frequency than that of the natural residue 2′-deoxycytidine

Scaling in animal group-size distributions

Local instrumental variables and latent variable models for identifying and bounding treatment effects

High-efficiency gene transfer into skeletal muscle mediated by electric pulses

A mutation in the heterotrimeric stimulatory guanine nucleotide binding protein α-subunit with impaired receptor-mediated activation because of elevated GTPase activity

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase

Rings and filaments of β protein from bacteriophage λ suggest a superfamily of recombination proteins

Assigning protein functions by comparative genome analysis: Protein phylogenetic profiles

Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-Å resolution

The Cys4 zinc finger of bacteriophage T7 primase in sequence-specific single-stranded DNA recognition

Location of translational initiation factor IF3 on the small ribosomal subunit

DRONC, an ecdysone-inducible Drosophila caspase

A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2

Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites

BglG, the transcriptional antiterminator of the bgl system, interacts with the β′ subunit of the Escherichia coli RNA polymerase

Universal conservation in translation initiation revealed by human and archaeal homologs of bacterial translation initiation factor IF2

The membrane-attached electron carrier cytochrome cy from Rhodobacter sphaeroides is functional in respiratory but not in photosynthetic electron transfer

The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria

Acyl homoserine-lactone quorum-sensing signal generation

A molecular trigger of lipid binding-induced opening of a helix bundle exchangeable apolipoprotein

Oligoribonuclease is an essential component of the mRNA decay pathway

Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: Evidence that 15-lipoxygenase is a mutator gene

Triple-helix formation of DNA oligomers with methylthiourea-linked nucleosides (DNmt): A kinetic and thermodynamic analysis

RNA polymerase switch in transcription of yeast rDNA: Role of transcription factor UAF (upstream activation factor) in silencing rDNA transcription by RNA polymerase II

Prebiotic cytosine synthesis: A critical analysis and implications for the origin of life

Two heads of myosin are better than one for generating force and motion

Singular value decomposition with self-modeling applied to determine bacteriorhodopsin intermediate spectra: Analysis of simulated data

Intermediate spectra and photocycle kinetics of the Asp96 → Asn mutant bacteriorhodopsin determined by singular value decomposition with self-modeling

Limiting dynamics of high-frequency electromechanical transduction of outer hair cells

Hormone-induced secretory and nuclear translocation of calmodulin: Oscillations of calmodulin concentration with the nucleus as an integrator

Tamoxifen inhibits acidification in cells independent of the estrogen receptor

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12–rapamycinassociated protein

Thyroid hormone, T3-dependent phosphorylation and translocation of Trip230 from the Golgi complex to the nucleus

Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity

A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3

The Cys₄ zinc finger of bacteriophage T7 primase in sequence-specific single-stranded DNA recognition

The membrane-attached electron carrier cytochrome c_y from Rhodobacter sphaeroides is functional in respiratory but not in photosynthetic electron transfer