Table of Contents

Commentaries

Commentary:
- M. Muthukumar
Chain entropy: Spoiler or benefactor in pattern recognition?
PNAS 1999 96:11690-11692
- See companion article on page 11707 in issue 21 of volume 96
Commentary:
- Randal J. Kaufman
Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: A new role for an old actor
PNAS 1999 96:11693-11695
- See companion article on page 11860 in issue 21 of volume 96
Commentary:
- Don Ganem
An advance in liver-specific gene delivery
PNAS 1999 96:11696-11697
- See companion article on page 10818 in issue 19 of volume 96
Commentary:
- Shoji Takada
Gō-ing for the prediction of protein folding mechanisms
PNAS 1999 96:11698-11700
- See companion article on page 11299 in issue 20 of volume 96
- See companion article on page 11305 in issue 20 of volume 96
- See companion article on page 11311 in issue 20 of volume 96

Editorial

Editorial:
- Diane M. Sullenberger,
- Kenneth R. Fulton,
- and Nicholas R. Cozzarelli
Redesign of PNAS: Getting ready for the millennium
PNAS 1999 96:11689

Physical Sciences

Applied Physical Sciences

Select this article
Physical Sciences - Applied Physical Sciences:
- K. M. Hill,
- D. V. Khakhar,
- J. F. Gilchrist,
- J. J. McCarthy,
- and J. M. Ottino
Segregation-driven organization in chaotic granular flows
PNAS 1999 96:11701-11706

Chemistry

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Physical Sciences - Chemistry:
- Aaron J. Golumbfskie,
- Vijay S. Pande,
- and Arup K. Chakraborty
Simulation of biomimetic recognition between polymers and surfaces
PNAS 1999 96:11707-11712
- See commentary article on page 11690 in issue 21 of volume 96
Select this article
Physical Sciences - Chemistry:
- M. Bixon,
- Bernd Giese,
- Stephan Wessely,
- Thomas Langenbacher,
- Maria E. Michel-Beyerle,
- and Joshua Jortner
Long-range charge hopping in DNA
PNAS 1999 96:11713-11716
Select this article
Physical Sciences - Chemistry - Biological Sciences - Biochemistry:
- Jacquin C. Niles,
- Samar Burney,
- Sukhjeet P. Singh,
- John S. Wishnok,
- and Steven R. Tannenbaum
Peroxynitrite reaction products of 3′,5′-di-O-acetyl-8-oxo-7,8-dihydro-2′-deoxyguanosine
PNAS 1999 96:11729-11734

Biological Sciences

Biophysics

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Biological Sciences - Biophysics:
- S. Sivasankar,
- W. Brieher,
- N. Lavrik,
- B. Gumbiner,
- and D. Leckband
Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains
PNAS 1999 96:11820-11824
Select this article
Biological Sciences - Biophysics:
- Robert K. Adair
A model of the detection of warmth and cold by cutaneous sensors through effects on voltage-gated membrane channels
PNAS 1999 96:11825-11829

Cell Biology

Select this article
Biological Sciences - Cell Biology:
- Michellee S. Chen,
- Kenneth S. K. Tung,
- Scott A. Coonrod,
- Yuji Takahashi,
- Dora Bigler,
- Alice Chang,
- Yoshio Yamashita,
- Paul W. Kincade,
- John C. Herr,
- and Judith M. White
Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin α6β1: Implications for murine fertilization
PNAS 1999 96:11830-11835
Select this article
Biological Sciences - Cell Biology:
- Hiroshi Takaishi,
- Hiroaki Konishi,
- Hidenori Matsuzaki,
- Yoshitaka Ono,
- Yasuhito Shirai,
- Naoaki Saito,
- Tadahiro Kitamura,
- Wataru Ogawa,
- Masato Kasuga,
- Ushio Kikkawa,
- and Yasutomi Nishizuka
Regulation of nuclear translocation of Forkhead transcription factor AFX by protein kinase B
PNAS 1999 96:11836-11841
Select this article
Biological Sciences - Cell Biology:
- Oliver Keminer,
- Jan-Peter Siebrasse,
- Katja Zerf,
- and Reiner Peters
Optical recording of signal-mediated protein transport through single nuclear pore complexes
PNAS 1999 96:11842-11847
Select this article
Biological Sciences - Cell Biology:
- Mathis Grossmann,
- Donald Metcalf,
- Julie Merryfull,
- Amer Beg,
- David Baltimore,
- and Steve Gerondakis
The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects
PNAS 1999 96:11848-11853
Select this article
Biological Sciences - Cell Biology:
- Maria José Caloca,
- Maria Laura Garcia-Bermejo,
- Peter M. Blumberg,
- Nancy E. Lewin,
- Elisabeth Kremmer,
- Harald Mischak,
- Shaomeng Wang,
- Kassoum Nacro,
- Bruno Bienfait,
- Victor E. Marquez,
- and Marcelo G. Kazanietz
β2-Chimaerin is a novel target for diacylglycerol: Binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain
PNAS 1999 96:11854-11859
Select this article
Biological Sciences - Cell Biology:
- Michael C. Yeung,
- Danny L. Chang,
- Randell E. Camantigue,
- and Allan S. Lau
Inhibitory role of the host apoptogenic gene PKR in the establishment of persistent infection by encephalomyocarditis virus in U937 cells
PNAS 1999 96:11860-11865
- See commentary article on page 11693 in issue 21 of volume 96
Select this article
Biological Sciences - Cell Biology:
- Olga N. Aprelikova,
- Bruno S. Fang,
- Eric G. Meissner,
- Shane Cotter,
- Mel Campbell,
- Aalok Kuthiala,
- Mika Bessho,
- Roy A. Jensen,
- and Edison T. Liu
BRCA1-associated growth arrest is RB-dependent
PNAS 1999 96:11866-11871
Select this article
Biological Sciences - Cell Biology:
- An Herreman,
- Dieter Hartmann,
- Wim Annaert,
- Paul Saftig,
- Katleen Craessaerts,
- Lutgarde Serneels,
- Lieve Umans,
- Vincent Schrijvers,
- Frédéric Checler,
- Hugo Vanderstichele,
- Veerle Baekelandt,
- Ralf Dressel,
- Philippe Cupers,
- Danny Huylebroeck,
- An Zwijsen,
- Fred Van Leuven,
- and Bart De Strooper
Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency
PNAS 1999 96:11872-11877
Select this article
Biological Sciences - Cell Biology:
- Nicole Zitzmann,
- Anand S. Mehta,
- Sandra Carrouée,
- Terry D. Butters,
- Frances M. Platt,
- John McCauley,
- Baruch S. Blumberg,
- Raymond A. Dwek,
- and Timothy M. Block
Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents
PNAS 1999 96:11878-11882

Developmental Biology

Select this article
Biological Sciences - Developmental Biology:
- Tetsunari Fukushige,
- Michael J. Hendzel,
- David P. Bazett-Jones,
- and James D. McGhee
Direct visualization of the elt-2 gut-specific GATA factor binding to a target promoter inside the living Caenorhabditis elegans embryo
PNAS 1999 96:11883-11888
Select this article
Biological Sciences - Developmental Biology:
- Ekaterina Y. Mantrova,
- Robert A. Schulz,
- and Tien Hsu
Oogenic function of the myogenic factor D-MEF2: Negative regulation of the Decapentaplegic receptor gene thick veins
PNAS 1999 96:11889-11894
Select this article
Biological Sciences - Developmental Biology:
- Esther Arman,
- Rebecca Haffner-Krausz,
- Marat Gorivodsky,
- and Peter Lonai
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
PNAS 1999 96:11895-11899
Select this article
Biological Sciences - Developmental Biology:
- Michel Tarpin,
- Walter J. Gehring,
- and Jacques Bièrne
Reverse homeosis in homeotically reconstructed ribbonworms
PNAS 1999 96:11900-11903

Evolution

Select this article
Biological Sciences - Evolution:
- Stephen Jay Gould
- and Elisabeth A. Lloyd
Individuality and adaptation across levels of selection: How shall we name and generalize the unit of Darwinism?
PNAS 1999 96:11904-11909
Select this article
Biological Sciences - Evolution:
- Douglas W. Schemske
- and H. D. Bradshaw, Jr.
Pollinator preference and the evolution of floral traits in monkeyflowers (Mimulus)
PNAS 1999 96:11910-11915
Select this article
Biological Sciences - Evolution:
- Gillian Cooper,
- Nigel J. Burroughs,
- David A. Rand,
- David C. Rubinsztein,
- and William Amos
Markov Chain Monte Carlo analysis of human Y-chromosome microsatellites provides evidence of biased mutation
PNAS 1999 96:11916-11921

Genetics

Select this article
Biological Sciences - Genetics:
- Valerie L. Gerlach,
- L. Aravind,
- Garrett Gotway,
- Roger A. Schultz,
- Eugene V. Koonin,
- and Errol C. Friedberg
Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily
PNAS 1999 96:11922-11927
- See commentary article on page 12224 in issue 22 of volume 96
Select this article
Biological Sciences - Genetics:
- Kara Manning,
- Muhsen Al-Dhalimy,
- Milton Finegold,
- and Markus Grompe
In vivo suppressor mutations correct a murine model of hereditary tyrosinemia type I
PNAS 1999 96:11928-11933
Select this article
Biological Sciences - Genetics:
- Xin Bi,
- Miriam Braunstein,
- Gan-Ju Shei,
- and James R. Broach
The yeast HML I silencer defines a heterochromatin domain boundary by directional establishment of silencing
PNAS 1999 96:11934-11939
Select this article

Biological Sciences - Genetics:

FROM THE COVER

Chain entropy: Spoiler or benefactor in pattern recognition?

Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: A new role for an old actor

An advance in liver-specific gene delivery

Gō-ing for the prediction of protein folding mechanisms

Redesign of PNAS: Getting ready for the millennium

Segregation-driven organization in chaotic granular flows

Simulation of biomimetic recognition between polymers and surfaces

Long-range charge hopping in DNA

Peroxynitrite reaction products of 3′,5′-di-O-acetyl-8-oxo-7,8-dihydro-2′-deoxyguanosine

Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus

Selection of antibodies for intracellular function using a two-hybrid in vivo system

Peroxynitrite reaction products of 3′,5′-di-O-acetyl-8-oxo-7,8-dihydro-2′-deoxyguanosine

DNA specificity enhanced by sequential binding of protein monomers

A multiplasmid approach to preparing large libraries of polyketides

Salt-induced detour through compact regions of the protein folding landscape

An internal targeting signal directing proteins into the mitochondrial intermembrane space

Cytidine 5′-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol

Correlation of deformability at a tRNA recognition site and aminoacylation specificity

Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochrome b2 import pathway

Glucocorticoid receptor inhibits transforming growth factor-β signaling by directly targeting the transcriptional activation function of Smad3

Nonstatistical binding of a protein to clustered carbohydrates

Active-site structure of the soluble quinoprotein glucose dehydrogenase complexed with methylhydrazine: A covalent cofactor-inhibitor complex

C-terminal DNA binding stimulates N-terminal phosphorylation of the outer membrane protein regulator OmpR from Escherichia coli

In vitro synthesis of the nucleotide loop of cobalamin by Salmonella typhimurium enzymes

Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA

A structural snapshot of base-pair opening in DNA

Interactions of Gh/transglutaminase with phospholipase Cδ1 and with GTP

Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains

A model of the detection of warmth and cold by cutaneous sensors through effects on voltage-gated membrane channels

Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin α6β1: Implications for murine fertilization

Regulation of nuclear translocation of Forkhead transcription factor AFX by protein kinase B

Optical recording of signal-mediated protein transport through single nuclear pore complexes

The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects

β2-Chimaerin is a novel target for diacylglycerol: Binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain

Inhibitory role of the host apoptogenic gene PKR in the establishment of persistent infection by encephalomyocarditis virus in U937 cells

BRCA1-associated growth arrest is RB-dependent

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents

Direct visualization of the elt-2 gut-specific GATA factor binding to a target promoter inside the living Caenorhabditis elegans embryo

Oogenic function of the myogenic factor D-MEF2: Negative regulation of the Decapentaplegic receptor gene thick veins

Fgfr2 is required for limb outgrowth and lung-branching morphogenesis

Reverse homeosis in homeotically reconstructed ribbonworms

Individuality and adaptation across levels of selection: How shall we name and generalize the unit of Darwinism?

Pollinator preference and the evolution of floral traits in monkeyflowers (Mimulus)

Markov Chain Monte Carlo analysis of human Y-chromosome microsatellites provides evidence of biased mutation

Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

In vivo suppressor mutations correct a murine model of hereditary tyrosinemia type I

The yeast HML I silencer defines a heterochromatin domain boundary by directional establishment of silencing

Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochrome b₂ import pathway

Interactions of G_h/transglutaminase with phospholipase Cδ1 and with GTP