Table of Contents

• Wei Huang,
• Zheng Shen,
• Norden E. Huang,
• and Yuan Cheng Fung

Use of intrinsic modes in biology: Examples of indicial response of pulmonary blood pressure to ± step hypoxia

• Zsolt Páles,
• Peter Volkmann,
• and R. Duncan Luce

Hyers–Ulam stability of functional equations with a square-symmetric operation

• Terrell L. Hill
• and Ralph V. Chamberlin

Extension of the thermodynamics of small systems to open metastable states: An example

• Calyampudi R. Rao

Geometry of circular vectors and pattern recognition of shape of a boundary

• Michihiko Kobayashi,
• Makoto Shinohara,
• Chigusa Sakoh,
• Michihiko Kataoka,
• and Sakayu Shimizu

Lactone-ring-cleaving enzyme: Genetic analysis, novel RNA editing, and evolutionary implications

• Alan J. Fischman,
• Yong M. Yu,
• E. Livni,
• John W. Babich,
• Vernon R. Young,
• Nathaniel M. Alpert,
• and Ronald G. Tompkins

Muscle protein synthesis by positron-emission tomography with l-[methyl-¹¹C]methionine in adult humans

• Birgit Schiøtt,
• Bo Brummerstedt Iversen,
• Georg Kent Hellerup Madsen,
• Finn Krebs Larsen,
• and Thomas C. Bruice

On the electronic nature of low-barrier hydrogen bonds in enzymatic reactions

• John Ralph,
• Ronald D. Hatfield,
• Joël Piquemal,
• Nabila Yahiaoui,
• Michel Pean,
• Catherine Lapierre,
• and Alain M. Boudet

NMR characterization of altered lignins extracted from tobacco plants down-regulated for lignification enzymes cinnamylalcohol dehydrogenase and cinnamoyl-CoA reductase

• Lori Giver,
• Anne Gershenson,
• Per-Ola Freskgard,
• and Frances H. Arnold

Directed evolution of a thermostable esterase

• Michael F. Giblin,
• Nannan Wang,
• Timothy J. Hoffman,
• Silvia S. Jurisson,
• and Thomas P. Quinn

Design and characterization of α-melanotropin peptide analogs cyclized through rhenium and technetium metal coordination

• Hartmut Michel

The mechanism of proton pumping by cytochrome c oxidase

• Hubert Dominique Becker
• and Daniel Kern

Thermus thermophilus: A link in evolution of the tRNA-dependent amino acid amidation pathways

• Alan W. Curnow,
• Debra L. Tumbula,
• Joanne T. Pelaschier,
• Bokkee Min,
• and Dieter Söll

Glutamyl-tRNA^Gln amidotransferase in Deinococcus radiodurans may be confined to asparagine biosynthesis

• Wenchuan Liang
• and James A. Spudich

Nucleotide-dependent conformational change near the fulcrum region in Dictyostelium myosin II

• Axel Nohturfft,
• Michael S. Brown,
• and Joseph L. Goldstein

Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N

• Najmoutin G. Abdulaev
• and Kevin D. Ridge

Light-induced exposure of the cytoplasmic end of transmembrane helix seven in rhodopsin

• Suwon Kim,
• Brenda Schilke,
• Elizabeth A. Craig,
• and Arthur L. Horwich

Folding in vivo of a newly translated yeast cytosolic enzyme is mediated by the SSA class of cytosolic yeast Hsp70 proteins

• Xinhai Ni
• and Lowell P. Hager

cDNA cloning of Batis maritima methyl chloride transferase and purification of the enzyme

• Peter Frank,
• Christa Braunshofer-Reiter,
• Ulrike Wintersberger,
• Rudolf Grimm,
• and Werner Büsen

Cloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HII

• Wei Liu
• and John K. Northup

The helical domain of a G protein α subunit is a regulator of its effector

• T. D. Sutherland,
• G. C. Unnithan,
• J. F. Andersen,
• P. H. Evans,
• M. B. Murataliev,
• L. Z. Szabo,
• E. A. Mash,
• W. S. Bowers,
• and R. Feyereisen

A cytochrome P450 terpenoid hydroxylase linked to the suppression of insect juvenile hormone synthesis

• Liliane A. Dickinson,
• Richard J. Gulizia,
• John W. Trauger,
• Eldon E. Baird,
• Donald E. Mosier,
• Joel M. Gottesfeld,
• and Peter B. Dervan

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

• Liang-Jun Yan
• and Rajindar S. Sohal

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

• Danaboyina Ramaiah,
• Yongzhi Kan,
• Troels Koch,
• Henrik Ørum,
• and Gary B. Schuster

Enzymatic reaction with unnatural substrates: DNA photolyase (Escherichia coli) recognizes and reverses thymine [2+2] dimers in the DNA strand of a DNA/PNA hybrid duplex

• John A. Schmiesing,
• Alexander R. Ball, Jr.,
• Heather C. Gregson,
• Janet M. Alderton,
• Sharleen Zhou,
• and Kyoko Yokomori

Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics

• Ravinder J. Singh,
• Steven P. A. Goss,
• Joy Joseph,
• and B. Kalyanaraman

Nitration of γ-tocopherol and oxidation of α-tocopherol by copper-zinc superoxide dismutase/H₂O₂/NO₂⁻: Role of nitrogen dioxide free radical

• Jennifer L. Schmitke,
• Lawrence J. Stern,
• and Alexander M. Klibanov

Comparison of x-ray crystal structures of an acyl-enzyme intermediate of subtilisin Carlsberg formed in anhydrous acetonitrile and in water

• David J. Steger,
• Anton Eberharter,
• Sam John,
• Patrick A. Grant,
• and Jerry L. Workman

Purified histone acetyltransferase complexes stimulate HIV-1 transcription from preassembled nucleosomal arrays

• R. A. Broglia,
• G. Tiana,
• S. Pasquali,
• H. E. Roman,
• and E. Vigezzi

Folding and aggregation of designed proteins

• Itamar Ronen,
• Hellmut Merkle,
• Kamil Ugurbil,
• and Gil Navon

Imaging of H₂¹⁷O distribution in the brain of a live rat by using proton-detected ¹⁷O MRI

• Betty J. Gaffney
• and Derek Marsh

High-frequency, spin-label EPR of nonaxial lipid ordering and motion in cholesterol-containing membranes

• C. M. Yengo,
• P. M. Fagnant,
• L. Chrin,
• A. S. Rovner,
• and C. L. Berger

Smooth muscle myosin mutants containing a single tryptophan reveal molecular interactions at the actin-binding interface

• B. M. Burkhart,
• N. Li,
• D. A. Langs,
• W. A. Pangborn,
• and W. L. Duax

The conducting form of gramicidin A is a right-handed double-stranded double helix

• Scott A. Peterson,
• Thomas Klabunde,
• Hilal A. Lashuel,
• Hans Purkey,
• James C. Sacchettini,
• and Jeffrey W. Kelly

Inhibiting transthyretin conformational changes that lead to amyloid fibril formation

• S. Sivasankar,
• S. Subramaniam,
• and D. Leckband

Direct molecular level measurements of the electrostatic properties of a protein surface

• Steven R. Wylie,
• Pei-jun Wu,
• Hitesh Patel,
• and Peter D. Chantler

A conventional myosin motor drives neurite outgrowth

• Junhao Mao,
• Huidong Yuan,
• Wei Xie,
• and Dianqing Wu

Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein α subunit Gα13

• Roxana Pey,
• Clarisa Vial,
• Gerald Schatten,
• and Mathias Hafner

Increase of intracellular Ca²⁺ and relocation of E-cadherin during experimental decompaction of mouse embryos

• Lih-Ching Hsu
• and Raymond L. White

BRCA1 is associated with the centrosome during mitosis

• Eugene V. Agapov,
• Ilya Frolov,
• Brett D. Lindenbach,
• Béla M. Prágai,
• Sondra Schlesinger,
• and Charles M. Rice

Noncytopathic Sindbis virus RNA vectors for heterologous gene expression

• Guang-Yuh Jauh,
• Andreas M. Fischer,
• Howard D. Grimes,
• Clarence A. Ryan, Jr.,
• and John C. Rogers

δ-Tonoplast intrinsic protein defines unique plant vacuole functions

• Linda A. Silveira,
• Janet L.