Table of Contents

• Joanna R. Long,
• John L. Dindot,
• Henry Zebroski,
• Suzanne Kiihne,
• Rutilio H. Clark,
• Allison A. Campbell,
• Patrick S. Stayton,
• and Gary P. Drobny

A peptide that inhibits hydroxyapatite growth is in an extended conformation on the crystal surface

• Wenge Zhong,
• Justin P. Gallivan,
• Yinong Zhang,
• Lintong Li,
• Henry A. Lester,
• and Dennis A. Dougherty

From ab initio quantum mechanics to molecular neurobiology: A cation–π binding site in the nicotinic receptor

• Hyuk Soon Choi,
• Seung Bum Suh,
• Seung Joo Cho,
• and Kwang S. Kim

Ionophores and receptors using cation-π interactions: Collarenes

• Jing Huang
• and Neil E. Forsberg

Role of calpain in skeletal-muscle protein degradation

• Wojciech P. Pawlowski
• and David A. Somers

Transgenic DNA integrated into the oat genome is frequently interspersed by host DNA

• Yongquan Xue,
• Lishan Zhao,
• Hung-wen Liu,
• and David H. Sherman

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae : Architecture of metabolic diversity

• Winslow S. Caughey,
• Lynne D. Raymond,
• Motohiro Horiuchi,
• and Byron Caughey

Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines

• K. Farid Ahmad,
• Christian K. Engel,
• and Gilbert G. Privé

Crystal structure of the BTB domain from PLZF

• Carolyn M. Slupsky,
• Lisa N. Gentile,
• Logan W. Donaldson,
• Cameron D. Mackereth,
• Jeffrey J. Seidel,
• Barbara J. Graves,
• and Lawrence P. McIntosh

Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site

• Joel R. Hoskins,
• Marie Pak,
• Michael R. Maurizi,
• and Sue Wickner

The role of the ClpA chaperone in proteolysis by ClpAP

• Joelle N. Pelletier,
• F.-X. Campbell-Valois,
• and Stephen W. Michnick

Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments

• Kogo Takamiya,
• Akihito Yamamoto,
• Keiko Furukawa,
• Jinmin Zhao,
• Satoshi Fukumoto,
• Shuji Yamashiro,
• Masahiko Okada,
• Masashi Haraguchi,
• Masashi Shin,
• Masao Kishikawa,
• Hiroshi Shiku,
• Shinichi Aizawa,
• and Koichi Furukawa

Complex gangliosides are essential in spermatogenesis of mice: Possible roles in the transport of testosterone

• W. Todd Lowther,
• Debra A. McMillen,
• Allen M. Orville,
• and Brian W. Matthews

The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase

• Zhongwei Li,
• Shilpa Pandit,
• and Murray P. Deutscher

Polyadenylation of stable RNA precursors in vivo

• Jue D. Wang,
• Melissa D. Michelitsch,
• and Jonathan S. Weissman

GroEL-GroES-mediated protein folding requires an intact central cavity

• Christin Tse,
• Terace M. Fletcher,
• and Jeffrey C. Hansen

Enhanced transcription factor access to arrays of histone H3/H4 tetramer⋅DNA complexes in vitro : Implications for replication and transcription

• Betina Corsico,
• David P. Cistola,
• Carl Frieden,
• and Judith Storch

The helical domain of intestinal fatty acid binding protein is critical for collisional transfer of fatty acids to phospholipid membranes

• Gisbert Schneider,
• Wieland Schrödl,
• Gerd Wallukat,
• Johannes Müller,
• Eberhard Nissen,
• Wolfgang Rönspeck,
• Paul Wrede,
• and Rudolf Kunze

Peptide design by artificial neural networks and computer-based evolutionary search

• Concha Caudevilla,
• Dolors Serra,
• Angel Miliar,
• Carles Codony,
• Guillermina Asins,
• Montserrat Bach,
• and Fausto G. Hegardt

Natural trans - splicing in carnitine octanoyltransferase pre-mRNAs in rat liver

• Tae Kook Kim,
• Tae Hoon Kim,
• and Tom Maniatis

Efficient recruitment of TFIIB and CBP-RNA polymerase II holoenzyme by an interferon-β enhanceosome in vitro

• Yong-Chao Ma
• and Xin-Yun Huang

Identification of the binding site for Gqα on its effector Bruton’s tyrosine kinase

• Dario De Cesare,
• Sylvie Jacquot,
• André Hanauer,
• and Paolo Sassone-Corsi

Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c- fos gene

• Göran Bertilsson,
• Jessica Heidrich,
• Kristian Svensson,
• Michael Åsman,
• Lena Jendeberg,
• Mona Sydow-Bäckman,
• Rolf Ohlsson,
• Hans Postlind,
• Patrik Blomquist,
• and Anders Berkenstam

Identification of a human nuclear receptor defines a new signaling pathway for CYP 3 A induction

• Rebecca W. Alexander,
• Brian E. Nordin,
• and Paul Schimmel

Activation of microhelix charging by localized helix destabilization

• Haobo Jiang,
• Yang Wang,
• and Michael R. Kanost

Pro-phenol oxidase activating proteinase from an insect, Manduca sexta: A bacteria-inducible protein similar to Drosophila easter

• Yingxia Wen,
• Zhenyu Yue,
• and Aaron J. Shatkin

Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism

• Andrew J. Rhomberg,
• Zachary Shriver,
• Klaus Biemann,
• and Ram Sasisekharan

Mass spectrometric evidence for the enzymatic mechanism of the depolymerization of heparin-like glycosaminoglycans by heparinase II

• Pedro Tranque,
• Michael C.-Y. Hu,
• Gerald M. Edelman,
• and Vincent P. Mauro

rRNA complementarity within mRNAs: A possible basis for mRNA-ribosome interactions and translational control

• Matthew J. Longley,
• Rajendra Prasad,
• Deepak K. Srivastava,
• Samuel H. Wilson,
• and William C. Copeland

Identification of 5′-deoxyribose phosphate lyase activity in human DNA polymerase γ and its role in mitochondrial base excision repair in vitro

• Shun-ichi Nakamura,
• Toshihiro Akisue,
• Hitoshi Jinnai,
• Tomohiro Hitomi,
• Sukumar Sarkar,
• Noriko Miwa,
• Taro Okada,
• Kimihisa Yoshida,
• Shun’ichi Kuroda,
• Ushio Kikkawa,
• and Yasutomi Nishizuka

Requirement of G M2 ganglioside activator for phospholipase D activation

• Kang Cai
• and Brian David Dynlacht

Activity and nature of p21 WAF1 complexes during the cell cycle

• Shunbin Xiong,
• Subrahmanyam S. Chirala,
• Matthew H. Hsu,
• and Salih J. Wakil

Identification of thyroid hormone response elements in the human fatty acid synthase promoter

• Luc Desnoyers
• and Miguel C. Seabra

Single prenyl-binding site on protein prenyl transferases

• Fredrik Höök,
• Michael Rodahl,
• Bengt Kasemo,
• and Peter Brzezinski

Structural changes in hemoglobin during adsorption to solid surfaces: Effects of pH, ionic strength, and ligand binding

• Yoko Kusumoto,
• Aleksey Lomakin,
• David B. Teplow,
• and George B. Benedek

Temperature dependence of amyloid β-protein fibrillization

• Jürgen Fritz,
• Andreas G. Katopodis,
• Frank Kolbinger,
• and Dario Anselmetti

Force-mediated kinetics of single P-selectin/ligand complexes observed by atomic force microscopy

• Ehud Gazit,
• Paolo La Rocca,
• Mark S. P. Sansom,
• and Yechiel Shai

The structure and organization within the membrane of the helices composing the pore-forming domain of Bacillus thuringiensis δ-endotoxin are consistent with an “umbrella-like” structure of the pore

• J. F. Leger,
• J. Robert,
• L. Bourdieu,
• D. Chatenay,
• and J. F. Marko

RecA binding to a single double-stranded DNA molecule: A possible role of DNA conformational fluctuations

• Costantino Vetriani,
• Dennis L. Maeder,
• Nicola Tolliday,
• Kitty S.-P. Yip,
• Timothy J. Stillman,
• K. Linda Britton,
• David W. Rice,
• Horst H. Klump,
• and Frank T. Robb

Protein thermostability above 100°C: A key role for ionic interactions

• Christian Rischel,
• Diane Spiedel,
• Justin P. Ridge,
• Michael R. Jones,
• Jacques Breton,
• Jean-Christophe Lambry,
• Jean-Louis Martin,
• and Marten H. Vos

Low frequency vibrational modes in proteins: Changes induced by point-mutations in the protein-cofactor matrix of bacterial reaction centers

• Dino A. De Angelis,
• Gero Miesenböck,
• Boris V. Zemelman,
• and James E. Rothman

PRIM: Proximity imaging of green fluorescent protein-tagged polypeptides

• Marie-Thérèse Guillam,
• Rémy Burcelin,
• and Bernard Thorens

Normal hepatic glucose production in the absence of GLUT2 reveals an alternative pathway for glucose release from hepatocytes

• Ulrike E. Knies,
• Heike A. Behrensdorf,
• Christopher A. Mitchell,
• Urban Deutsch,
• Werner Risau,
• Hannes C. A. Drexler,
• and Matthias Clauss

Regulation of endothelial monocyte-activating polypeptide II release by apoptosis

• Inês Chaves,
• Joost Zomerdijk,
• Anita Dirks-Mulder,
• Roeland W. Dirks,
• Anton K. Raap,
• and Piet Borst

Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei

• Zhigang Weng,
• Anne-Catherine Fluckiger,
• Sazuku Nisitani,
• Matthew I. Wahl,
• Lu Q. Le,
• Charity A. Hunter,
• Anthony A. Fernal,
• Michelle M. Le Beau,
• and Owen N. Witte

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G 2 /M

• Luc De Vries,
• Xiaojing Lou,
• Grace Zhao,
• Bin Zheng,
• and Marilyn Gist Farquhar

GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP

• Zhigang Xie,
• Min Fang,