Table of Contents

• Gitte Neubauer,
• Alexander Gottschalk,
• Patrizia Fabrizio,
• Bertrand Séraphin,
• Reinhard Lührmann,
• and Matthias Mann

Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry

• Satoshi Fujita,
• Tetsuhiko Koguma,
• Jun Ohkawa,
• Kazuyuki Mori,
• Takeo Kohda,
• Hideo Kise,
• Satoshi Nishikawa,
• Masahiro Iwakura,
• and Kazunari Taira

Discrimination of a single base change in a ribozyme using the gene for dihydrofolate reductase as a selective marker in  Escherichia coli

• Fredrik Svensson,
• Carolina Ceriani,
• Eva Lövkvist Wallström,
• Inger Kockum,
• Israel D. Algranati,
• Olle Heby,
• and Lo Persson

Cloning of a trypanosomatid gene coding for an ornithine decarboxylase that is metabolically unstable even though it lacks the C-terminal degradation domain

• Ivan Brukner,
• Abdellah Belmaaza,
• and Pierre Chartrand

Differential behavior of curved DNA upon untwisting

• Guangxia Gao,
• Marianna Orlova,
• Millie M. Georgiadis,
• Wayne A. Hendrickson,
• and Stephen P. Goff

Conferring RNA polymerase Activity to a DNA polymerase: A single residue in reverse transcriptase controls substrate selection

• Elizabeth A. Burks,
• Gang Chen,
• George Georgiou,
• and Brent L. Iverson

In vitro scanning saturation mutagenesis of an antibody binding pocket

• Ick Young Kim,
• M. Jorge Guimarães,
• Albert Zlotnik,
• J. Fernando Bazan,
• and Thressa C. Stadtman

Fetal mouse selenophosphate synthetase 2 (SPS2): Characterization of the cysteine mutant form overproduced in a baculovirus–insect cell system

• Vincent P. Mauro
• and Gerald M. Edelman

rRNA-like sequences occur in diverse primary transcripts: Implications for the control of gene expression

• John R. Hepler,
• David M. Berman,
• Alfred G. Gilman,
• and Tohru Kozasa

RGS4 and GAIP are GTPase-activating proteins for G qα and block activation of phospholipase Cβ by γ-thio-GTP-G qα

• Xia Wang,
• Stig K. Hansen,
• Ryan Ratts,
• Sharleen Zhou,
• Amy J. Snook,
• and William Zehring

Drosophila TFIIE: Purification, cloning, and functional reconstitution

• Akio Kuroda
• and Arthur Kornberg

Polyphosphate kinase as a nucleoside diphosphate kinase in Escherichia coli and  Pseudomonas aeruginosa

• Evan R. Lewis,
• Kelly M. Winterberg,
• and Anthony L. Fink

A point mutation leads to altered product specificity in β-lactamase catalysis

• Kevin M. Pumiglia
• and Stuart J. Decker

Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

• Efstratios Stratikos
• and Peter G. W. Gettins

Major proteinase movement upon stable serpin–proteinase complex formation

• Barbara J. Wedel,
• David C. Foster,
• Deborah E. Miller,
• and David L. Garbers

A mutation of the atrial natriuretic peptide (guanylyl cyclase-A) receptor results in a constitutively hyperactive enzyme

• Ravindra C. Gupta,
• L. Rochelle Bazemore,
• Efim I. Golub,
• and Charles M. Radding

Activities of human recombination protein Rad51

• Joan K. Heath,
• Sara J. White,
• Cameron N. Johnstone,
• Bruno Catimel,
• Richard J. Simpson,
• Robert L. Moritz,
• Guo-Fen Tu,
• Hong Ji,
• Robert H. Whitehead,
• Leo C. Groenen,
• Andrew M. Scott,
• Gerd Ritter,
• Leonard Cohen,
• Sydney Welt,
• Lloyd J. Old,
• Edouard C. Nice,
• and Antony W. Burgess

The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily

• Joan Riera,
• Frank T. Robb,
• Robert Weiss,
• and Marc Fontecave

Ribonucleotide reductase in the archaeon Pyrococcus furiosus : A critical enzyme in the evolution of DNA genomes?

• Ella Bedford,
• Stanley Tabor,
• and Charles C. Richardson

The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I

• Takashi Kanamori,
• Shuh-Ichi Nishikawa,
• Injae Shin,
• Peter G. Schultz,
• and Toshiya Endo

Probing the environment along the protein import pathways in yeast mitochondria by site-specific photocrosslinking

• Michael D. Davis,
• Michael A. Parniak,
• Seymour Kaufman,
• and Ellis Kempner

The role of phenylalanine in structure–function relationships of phenylalanine hydroxylase revealed by radiation target analysis

• Yuri L. Lyubchenko
• and Luda S. Shlyakhtenko

Visualization of supercoiled DNA with atomic force microscopy  in situ

• Jianke Li,
• April N. Meyer,
• and Daniel J. Donoghue

Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation

• Frazier T. Stevenson,
• Johanna Turck,
• Richard M. Locksley,
• and David H. Lovett

The N-terminal propiece of interleukin 1α is a transforming nuclear oncoprotein

• F. Michael Yakes
• and Bennett Van Houten

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

• Th. Enderle,
• T. Ha,
• D. F. Ogletree,
• D. S. Chemla,
• C. Magowan,
• and S. Weiss

Membrane specific mapping and colocalization of malarial and host skeletal proteins in the Plasmodium falciparum infected erythrocyte by dual-color near-field scanning optical microscopy

• Hoyun Lee,
• James M. Larner,
• and Joyce L. Hamlin

A p53-independent damage-sensing mechanism that functions as a checkpoint at the G 1 /S transition in Chinese hamster ovary cells

• Arturo Sala,
• Mondira Kundu,
• Ida Casella,
• Andrew Engelhard,
• Bruno Calabretta,
• Luigi Grasso,
• Marco G. Paggi,
• Antonio Giordano,
• Roger J. Watson,
• Kamel Khalili,
• and Cesare Peschle

Activation of human B-MYB by cyclins

• Andrea Brüggemann,
• Walter Stühmer,
• and Luis A. Pardo

Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus  oocytes

• Shadrack R. Moephuli,
• Norman W. Klein,
• Michael T. Baldwin,
• and Hallie M. Krider

Effects of methionine on the cytoplasmic distribution of actin and tubulin during neural tube closure in rat embryos

• Nicola Saino,
• Anna Maria Bolzern,
• and Anders Pape Møller

Immunocompetence, ornamentation, and viability of male barn swallows ( Hirundo rustica )

• Olaf Malek,
• Axel Brennicke,
• and Volker Knoop

Evolution of trans-splicing plant mitochondrial introns in pre-Permian times

• Joe Pogliano,
• Kit Pogliano,
• David S. Weiss,
• Richard Losick,
• and Jon Beckwith

Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites

• M. Q. Zhang

Identification of protein coding regions in the human genome by quadratic discriminant analysis

• Dong-Er Zhang,
• Pu Zhang,
• Nai-dy Wang,
• Christopher J. Hetherington,
• Gretchen J. Darlington,
• and Daniel G. Tenen

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice

• Jay H. Chung,
• Adam C. Bell,
• and Gary Felsenfeld

Characterization of the chicken β-globin insulator

• Yuen Ho,
• Stephen Mason,
• Ryuji Kobayashi,
• Merl Hoekstra,
• and Brenda Andrews

Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae

• Robert Freedman,
• Hilary Coon,
• Marina Myles-Worsley,
• Avi Orr-Urtreger,
• Ann Olincy,
• Ashley Davis,
• Mihael Polymeropoulos,
• John Holik,
• Jan Hopkins,
• Mark Hoff,
• Judy Rosenthal,
• Merilyne C. Waldo,
• Fred Reimherr,
• Paul Wender,
• Jeffrey Yaw,
• David A. Young,
• Charles R. Breese,
• Catherine Adams,
• David Patterson,
• Lawrence E. Adler,
• Leonid Kruglyak,
• Sherry Leonard,
• and William Byerley

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

• Susumu Shiota
• and Hiroaki Nakayama

UV endonuclease of Micrococcus luteus , a cyclobutane pyrimidine dimer–DNA glycosylase/abasic lyase: Cloning and characterization of the gene

• Konstantin E. Balashov,
• Derek R. Smith,
• Samia J. Khoury,
• David A. Hafler,
• and Howard L. Weiner

Increased interleukin 12 production in progressive multiple sclerosis: Induction by activated CD4 + T cells via CD40 ligand

• Weiyi Yang
• and Stephen Desiderio

BAP-135, a target for Bruton’s tyrosine kinase in response to B cell receptor engagement

• Dubravka Drabek,
• Selina Raguz,
• Ton P. M. De Wit,
• Gemma M. Dingjan,
• Huub F. J. Savelkoul,
• Frank Grosveld,
• and Rudolf W. Hendriks

Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region

• Chih-Pin Liu,
• Wei-Jen Lin,
• Manley Huang,
• John W. Kappler,
• and Philippa Marrack

Development and function of T cells in T cell antigen receptor/CD3 ζ knockout mice reconstituted with FcɛRI γ

• Gernot Stuhler
• and Stuart F. Schlossman

Antigen organization regulates cluster formation and induction of cytotoxic T lymphocytes by helper T cell subsets

• Christopher A. Nelson,
• Ilan Vidavsky,
• Nicholas J. Viner,
• Michael L. Gross,
• and Emil R. Unanue

Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules

• Leslie P. Cousens,
• Jordan S. Orange,
• Helen C. Su,
• and Christine A. Biron

Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endogenously during viral infection

• Martin F. Bachmann,
• Thomas M. Kündig,
• Hans Hengartner,
• and Rolf M. Zinkernagel

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without “memory T cells”?

• Helen Tighe,
• Klaus Warnatz,