Table of Contents

• Glenn McGall,
• Jeff Labadie,
• Phil Brock,
• Greg Wallraff,
• Tiffany Nguyen,
• and William Hinsberg

Light-directed synthesis of high-density oligonucleotide arrays using semiconductor photoresists

• W. Cai,
• B. B. Das,
• Feng Liu,
• M. Zevallos,
• M. Lax,
• and R. R. Alfano

Time-resolved optical diffusion tomographic image reconstruction in highly scattering turbid media

• Robin J. Parks,
• Liane Chen,
• Martina Anton,
• Uma Sankar,
• Michael A. Rudnicki,
• and Frank L. Graham

A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal

• Hristo B. Houbaviy,
• Anny Usheva,
• Thomas Shenk,
• and Stephen K. Burley

Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator

• Koji Furukawa,
• Masayuki Oda,
• and Haruki Nakamura

A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy

• Travis Stams,
• Satish K. Nair,
• Torayuki Okuyama,
• Abdul Waheed,
• William S. Sly,
• and David W. Christianson

Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-Å resolution

• Alvaro N. A. Monteiro,
• Avery August,
• and Hidesaburo Hanafusa

Evidence for a transcriptional activation function of BRCA1 C-terminal region

• Andrea C. Porchia
• and Graciela L. Salerno

Sucrose biosynthesis in a prokaryotic organism: Presence of two sucrose-phosphate synthases in Anabaena with remarkable differences compared with the plant enzymes

• W. Sean Davidson,
• Theodore Hazlett,
• William W. Mantulin,
• and Ana Jonas

The role of apolipoprotein AI domains in lipid binding

• Naoko Tanese,
• Daman Saluja,
• Milo F. Vassallo,
• Jin-Long Chen,
• and Arie Admon

Molecular cloning and analysis of two subunits of the human TFIID complex: hTAF II 130 and hTAF II 100

• Haruki Niwa,
• Satoshi Inouye,
• Takashi Hirano,
• Tatsuki Matsuno,
• Satoshi Kojima,
• Masayuki Kubota,
• Mamoru Ohashi,
• and Frederick I. Tsuji

Chemical nature of the light emitter of the Aequorea green fluorescent protein

• Christian Bailly,
• Dominique Payet,
• Andrew A. Travers,
• and Michael J. Waring

PCR-based development of DNA substrates containing modified bases: An efficient system for investigating the role of the exocyclic groups in chemical and structural recognition by minor groove binding drugs and proteins

• Samir Acharya,
• Teresa Wilson,
• Scott Gradia,
• Michael F. Kane,
• Shawn Guerrette,
• Gerald T. Marsischky,
• Richard Kolodner,
• and Richard Fishel

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

• Kay Keyer
• and James A. Imlay

Superoxide accelerates DNA damage by elevating free-iron levels

• Christian W. Siebel
• and Christine Guthrie

The essential yeast RNA binding protein Npl3p is methylated

• Shinya Tamai,
• Abdul Waheed,
• Lee B. Cody,
• and William S. Sly

Gly-63 → Gln substitution adjacent to His-64 in rodent carbonic anhydrase IVs largely explains their reduced activity

• Nagappan Mathialagan
• and Thomas R. Hansen

Pepsin-inhibitory activity of the uterine serpins

• Ronglan Zheng,
• Timothy M. Jenkins,
• and Robert Craigie

Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

• Arieh Warshel
• and Arno Papazyan

Energy considerations show that low-barrier hydrogen bonds do not offer a catalytic advantage over ordinary hydrogen bonds

• Blake R. Peterson,
• Li Jing Sun,
• and Gregory L. Verdine

A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1

• ChoonJu Jeon
• and Kan Agarwal

Fidelity of RNA polymerase II transcription controlled by elongation factor TFIIS

• Virginia M. Weis,
• Andrea L. Small,
• and Margaret J. McFall-Ngai

A peroxidase related to the mammalian antimicrobial protein myeloperoxidase in the Euprymna–Vibrio  mutualism

• Irina Khrebtukova
• and Robert J. Spreitzer

Elimination of the Chlamydomonas gene family that encodes the small subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase

• Kellie L. Watson,
• Margaret M. Chou,
• John Blenis,
• William M. Gelbart,
• and Raymond L. Erikson

A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa S6 kinase gene

• H. Lauble,
• M. C. Kennedy,
• M. H. Emptage,
• H. Beinert,
• and C. D. Stout

The reaction of fluorocitrate with aconitase and the crystal structure of the enzyme-inhibitor complex

• Ohkmae K. Park,
• Timothy S. Schaefer,
• and Daniel Nathans

In vitro activation of Stat3 by epidermal growth factor receptor kinase

• Axel Nohturfft,
• Xianxin Hua,
• Michael S. Brown,
• and Joseph L. Goldstein

Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines

• Shubh D. Sharma,
• Jinwen Jiang,
• Mac E. Hadley,
• David L. Bentley,
• and Victor J. Hruby

Melanotropic peptide-conjugated beads for microscopic visualization and characterization of melanoma melanotropin receptors

• Cheryl Y. Brown,
• Cathy A. Lagnado,
• and Gregory J. Goodall

A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A+U-rich elements

• Andrew F. X. Goldberg
• and Robert S. Molday

Defective subunit assembly underlies a digenic form of retinitis pigmentosa linked to mutations in peripherin/rds and rom-1

• Futoshi Arakane,
• Teruo Sugawara,
• Hideaki Nishino,
• Zhiming Liu,
• John A. Holt,
• Debkumar Pain,
• Douglas M. Stocco,
• Walter L. Miller,
• and Jerome F. Strauss, III

Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: Implications for the mechanism of StAR action

• B. Hang,
• A. Chenna,
• H. Fraenkel-Conrat,
• and B. Singer

An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5′ cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site

• David A. Alcorta,
• Yue Xiong,
• Dawn Phelps,
• Greg Hannon,
• David Beach,
• and J. Carl Barrett

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

• Eveline Baumgart,
• Johannes C. T. Vanhooren,
• Mark Fransen,
• Peter Marynen,
• Magda Puype,
• Joël Vandekerckhove,
• Jack A. M. Leunissen,
• H. Dariush Fahimi,
• Guy P. Mannaerts,
• and Paul P. Van Veldhoven

Molecular characterization of the human peroxisomal branchedchain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome

• Mark T. Worthington,
• Barbara T. A