Find articles in this issue containing these words:

THIS WEEK IN PNAS

In This Issue
PNAS 2008 105: 6209-6210. [Full Text] [PDF]  

LETTERS (Online only)

Claudia Bagni

On BC1 RNA and the fragile X mental retardation protein
PNAS 2008 105: E19; published online on April 15, 2008, 10.1073/pnas.0801034105 [Extract] [Full Text] [PDF]  

Dan Blazer, Gregory C. Gray, Matthew Hotopf, Gary Macfarlane, Malcolm Sim, Tyler C. Smith, and Simon Wessely

Acetylcholinesterase inhibition and Gulf War illnesses: Conclusions are not supported by independent reviews of the same evidence
PNAS 2008 105: E20; published online on April 23, 2008, 10.1073/pnas.0802669105 [Extract] [Full Text] [PDF]  

COMMENTARIES

Bob Eisenberg

Engineering channels: Atomic biology
PNAS 2008 105: 6211-6212; published online on April 28, 2008, 10.1073/pnas.0802435105 [Extract] [Full Text] [PDF]  
See companion article on page 6272

Jenny Tong, Paul T. Pfluger, and Matthias H. Tschöp

Gastric O-acyl transferase activates hunger signal to the brain
PNAS 2008 105: 6213-6214; published online on April 28, 2008, 10.1073/pnas.0802461105 [Extract] [Full Text] [PDF]  
See companion article on page 6320

PERSPECTIVES

Harry Rubin

Cell–cell contact interactions conditionally determine suppression and selection of the neoplastic phenotype
PNAS 2008 105: 6215-6221; published online on April 23, 2008, 10.1073/pnas.0800747105 [Abstract] [Full Text] [Figures Only] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

Yoichiro Mori, Glenn I. Fishman, and Charles S. Peskin

Ephaptic conduction in a cardiac strand model with 3D electrodiffusion
PNAS 2008 105: 6463-6468; published online on April 23, 2008, 10.1073/pnas.0801089105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Applied Physical Sciences

Chemistry

Xingan Wang, Wenrui Dong, Minghui Qiu, Zefeng Ren, Li Che, Dongxu Dai, Xiuyan Wang, Xueming Yang, Zhigang Sun, Bina Fu, Soo-Y. Lee, Xin Xu, and Dong H. Zhang

HF(v' = 3) forward scattering in the F + H₂ reaction: Shape resonance and slow-down mechanism
PNAS 2008 105: 6227-6231; published online on April 23, 2008, 10.1073/pnas.0710840105 [Abstract] [Full Text] [Figures Only] [PDF]  

Tsutomu Nakamura, Takahiko Yamamoto, Manabu Abe, Hiroyoshi Matsumura, Yoshihisa Hagihara, Tadashi Goto, Takafumi Yamaguchi, and Tsuyoshi Inoue

Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
PNAS 2008 105: 6238-6242; published online on April 24, 2008, 10.1073/pnas.0709822105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

SOCIAL SCIENCES

Anthropology

David L. Lentz, Mary DeLand Pohl, José Luis Alvarado, Somayeh Tarighat, and Robert Bye

Sunflower (Helianthus annuus L.) as a pre-Columbian domesticate in Mexico
PNAS 2008 105: 6232-6237; published online on April 28, 2008, 10.1073/pnas.0711760105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

BIOLOGICAL SCIENCES

Biochemistry

Tsutomu Nakamura, Takahiko Yamamoto, Manabu Abe, Hiroyoshi Matsumura, Yoshihisa Hagihara, Tadashi Goto, Takafumi Yamaguchi, and Tsuyoshi Inoue

Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
PNAS 2008 105: 6238-6242; published online on April 24, 2008, 10.1073/pnas.0709822105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kevin C. Slep, Michele A. Kercher, Thomas Wieland, Ching-Kang Chen, Melvin I. Simon, and Paul B. Sigler

Molecular architecture of G_o and the structural basis for RGS16-mediated deactivation
PNAS 2008 105: 6243-6248; published online on April 23, 2008, 10.1073/pnas.0801569105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hui Zhou, Jixun Zhan, Kenji Watanabe, Xinkai Xie, and Yi Tang

A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
PNAS 2008 105: 6249-6254; published online on April 21, 2008, 10.1073/pnas.0800657105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biophysics

Ville R. I. Kaila, Michael I. Verkhovsky, Gerhard Hummer, and Mårten Wikström

Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase
PNAS 2008 105: 6255-6259; published online on April 22, 2008, 10.1073/pnas.0800770105 [Abstract] [Full Text] [Figures Only] [PDF]  

Carsten Kötting, Angela Kallenbach, Yan Suveyzdis, Alfred Wittinghofer, and Klaus Gerwert

The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy
PNAS 2008 105: 6260-6265; published online on April 23, 2008, 10.1073/pnas.0712095105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Erik Persson and Bertil Halle

Cell water dynamics on multiple time scales
PNAS 2008 105: 6266-6271; published online on April 24, 2008, 10.1073/pnas.0709585105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Min Chen, Syma Khalid, Mark S. P. Sansom, and Hagan Bayley From the Cover: Outer membrane protein G: Engineering a quiet pore for biosensing PNAS 2008 105: 6272-6277; published online on April 28, 2008, 10.1073/pnas.0711561105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]   See Commentary on page 6211

Daniel J. Felitsky, Michael A. Lietzow, H. Jane Dyson, and Peter E. Wright

Modeling transient collapsed states of an unfolded protein to provide insights into early folding events
PNAS 2008 105: 6278-6283; published online on April 23, 2008, 10.1073/pnas.0710641105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jonathan J. Helmus, Krystyna Surewicz, Philippe S. Nadaud, Witold K. Surewicz, and Christopher P. Jaroniec

Molecular conformation and dynamics of the Y145Stop variant of human prion protein in amyloid fibrils
PNAS 2008 105: 6284-6289; published online on April 24, 2008, 10.1073/pnas.0711716105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Dian Jiao, Pavel A. Golubkov, Thomas A. Darden, and Pengyu Ren

Calculation of protein–ligand binding free energy by using a polarizable potential
PNAS 2008 105: 6290-6295; published online on April 21, 2008, 10.1073/pnas.0711686105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Johan Qvist, Monika Davidovic, Donald Hamelberg, and Bertil Halle From the Cover: A dry ligand-binding cavity in a solvated protein PNAS 2008 105: 6296-6301; published online on April 21, 2008, 10.1073/pnas.0709844105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] [Supporting Information]

Cell Biology

Aurelie Doyotte, Aleksandr Mironov, Edward McKenzie, and Philip Woodman

The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis
PNAS 2008 105: 6308-6313; published online on April 23, 2008, 10.1073/pnas.0707601105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kedar Hastak, Rajib K. Paul, Mukesh K. Agarwal, Vijay S. Thakur, A. R. M. Ruhul Amin, Sudesh Agrawal, R. Michael Sramkoski, James W. Jacobberger, Mark W. Jackson, George R. Stark, and Munna L. Agarwal

DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation
PNAS 2008 105: 6314-6319; published online on April 23, 2008, 10.1073/pnas.0802080105 [Abstract] [Full Text] [Figures Only] [PDF]  

Jesus A. Gutierrez, Patricia J. Solenberg, Douglas R. Perkins, Jill A. Willency, Michael D. Knierman, Zhaoyan Jin, Derrick R. Witcher, Shuang Luo, Jude E. Onyia, and John E. Hale From the Cover: Ghrelin octanoylation mediated by an orphan lipid transferase PNAS 2008 105: 6320-6325; published online on April 28, 2008, 10.1073/pnas.0800708105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE   See Commentary on page 6213

Developmental Biology

Anatoli S. Gleiberman, Tatyana Michurina, Juan M. Encinas, Jose L. Roig, Peter Krasnov, Francesca Balordi, Gord Fishell, Michael G. Rosenfeld, and Grigori Enikolopov Genetic approaches identify adult pituitary stem cells PNAS 2008 105: 6332-6337; published online on April 24, 2008, 10.1073/pnas.0801644105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Jan C. Holstege, Wim de Graaff, Mehdi Hossaini, Sebastian Cardona Cano, Dick Jaarsma, Eric van den Akker, and Jacqueline Deschamps

Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice
PNAS 2008 105: 6338-6343; published online on April 22, 2008, 10.1073/pnas.0802176105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

Kelly Gravuer, Jon J. Sullivan, Peter A. Williams, and Richard P. Duncan

Strong human association with plant invasion success for Trifolium introductions to New Zealand
PNAS 2008 105: 6344-6349; published online on April 21, 2008, 10.1073/pnas.0712026105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

John M. Burns, Daniel H. Janzen, Mehrdad Hajibabaei, Winnie Hallwachs, and Paul D. N. Hebert DNA barcodes and cryptic species of skipper butterflies in the genus Perichares in Area de Conservación Guanacaste, Costa Rica PNAS 2008 105: 6350-6355; published online on April 24, 2008, 10.1073/pnas.0712181105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Evolution

Michael Balke, Jesús Gómez-Zurita, Ignacio Ribera, Angel Viloria, Anne Zillikens, Josephina Steiner, Mauricio García, Lars Hendrich, and Alfried P. Vogler

Ancient associations of aquatic beetles and tank bromeliads in the Neotropical forest canopy
PNAS 2008 105: 6356-6361; published online on April 23, 2008, 10.1073/pnas.0710368105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hurng-Yi Wang, Yonggui Fu, Mary Sara McPeek, Xuemei Lu, Sergey Nuzhdin, Anlong Xu, Jian Lu, Mao-Lien Wu, and Chung-I Wu Complex genetic interactions underlying expression differences between Drosophila races: Analysis of chromosome substitutions PNAS 2008 105: 6362-6367; published online on April 22, 2008, 10.1073/pnas.0711774105 [Abstract] [Full Text] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Genetics

Thomas Flatt, Kyung-Jin Min, Cecilia D'Alterio, Eugenia Villa-Cuesta, John Cumbers, Ruth Lehmann, D. Leanne Jones, and Marc Tatar

Drosophila germ-line modulation of insulin signaling and lifespan
PNAS 2008 105: 6368-6373; published online on April 23, 2008, 10.1073/pnas.0709128105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Immunology

Arunika Mukhopadhaya, Tadashi Hanafusa, Irene Jarchum, Yi-Guang Chen, Yoshiko Iwai, David V. Serreze, Ralph M. Steinman, Kristin V. Tarbell, and Teresa P. DiLorenzo

Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8⁺ T cells in NOD mice
PNAS 2008 105: 6374-6379; published online on April 22, 2008, 10.1073/pnas.0802644105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Medical Sciences

Nigel P. S. Crawford, Jude Alsarraj, Luanne Lukes, Renard C. Walker, Jennifer S. Officewala, Howard H. Yang, Maxwell P. Lee, Keiko Ozato, and Kent W. Hunter

Bromodomain 4 activation predicts breast cancer survival
PNAS 2008 105: 6380-6385; published online on April 21, 2008, 10.1073/pnas.0710331105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Utako Yokoyama, Hemal H. Patel, N. Chin Lai, Nakon Aroonsakool, David M. Roth, and Paul A. Insel

The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals
PNAS 2008 105: 6386-6391; published online on April 23, 2008, 10.1073/pnas.0801490105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cecilia Sahlgren, Maria V. Gustafsson, Shaobo Jin, Lorenz Poellinger, and Urban Lendahl

Notch signaling mediates hypoxia-induced tumor cell migration and invasion
PNAS 2008 105: 6392-6397; published online on April 21, 2008, 10.1073/pnas.0802047105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Peter Ellekvist, Jorge Maciel, Godfree Mlambo, Christina H. Ricke, Hanne Colding, Dan A. Klaerke, and Nirbhay Kumar

Critical role of a K⁺ channel in Plasmodium berghei transmission revealed by targeted gene disruption
PNAS 2008 105: 6398-6402; published online on April 23, 2008, 10.1073/pnas.0802384105 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

Sonja Schulmeister, Michaela Ruttorf, Sebastian Thiem, David Kentner, Dirk Lebiedz, and Victor Sourjik

Protein exchange dynamics at chemoreceptor clusters in Escherichia coli
PNAS 2008 105: 6403-6408; published online on April 21, 2008, 10.1073/pnas.0710611105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Neuroscience

Sébastien S. Hébert, Katrien Horré, Laura Nicolaï, Aikaterini S. Papadopoulou, Wim Mandemakers, Asli N. Silahtaroglu, Sakari Kauppinen, André Delacourte, and Bart De Strooper Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression PNAS 2008 105: 6415-6420; published online on April 23, 2008, 10.1073/pnas.0710263105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Marc F. Bolliger, Jimin Pei, Stephan Maxeiner, Antony A. Boucard, Nick V. Grishin, and Thomas C. Südhof

Unusually rapid evolution of Neuroligin-4 in mice
PNAS 2008 105: 6421-6426; published online on April 23, 2008, 10.1073/pnas.0801383105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Eugene M. Silinsky

Selective disruption of the mammalian secretory apparatus enhances or eliminates calcium current modulation in nerve endings
PNAS 2008 105: 6427-6432; published online on April 17, 2008, 10.1073/pnas.0708814105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yuanfeng Xia, Guirong Wang, Daniela Buscariollo, R. Jason Pitts, Heidi Wenger, and Laurence J. Zwiebel

The molecular and cellular basis of olfactory-driven behavior in Anopheles gambiae larvae
PNAS 2008 105: 6433-6438; published online on April 21, 2008, 10.1073/pnas.0801007105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Brian S. Johnson, J. Michael McCaffery, Susan Lindquist, and Aaron D. Gitler

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
PNAS 2008 105: 6439-6444; published online on April 23, 2008, 10.1073/pnas.0802082105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Joel Jakobsson, Helge Gad, Fredrik Andersson, Peter Löw, Oleg Shupliakov, and Lennart Brodin

Role of epsin 1 in synaptic vesicle endocytosis
PNAS 2008 105: 6445-6450; published online on April 22, 2008, 10.1073/pnas.0710267105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nicolas Stifani, Adriana R. O. Freitas, Anna Liakhovitskaia, Alexander Medvinsky, Artur Kania, and Stefano Stifani

Suppression of interneuron programs and maintenance of selected spinal motor neuron fates by the transcription factor AML1/Runx1
PNAS 2008 105: 6451-6456; published online on April 21, 2008, 10.1073/pnas.0711299105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Pharmacology

Meera Soundararajan, Francis S. Willard, Adam J. Kimple, Andrew P. Turnbull, Linda J. Ball, Guillaume A. Schoch, Carina Gileadi, Oleg Y. Fedorov, Elizabeth F. Dowler, Victoria A. Higman, Stephanie Q. Hutsell, Michael Sundström, Declan A. Doyle, and David P. Siderovski

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein -subunits
PNAS 2008 105: 6457-6462; published online on April 23, 2008, 10.1073/pnas.0801508105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Physiology

Yoichiro Mori, Glenn I. Fishman, and Charles S. Peskin

Ephaptic conduction in a cardiac strand model with 3D electrodiffusion
PNAS 2008 105: 6463-6468; published online on April 23, 2008, 10.1073/pnas.0801089105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Swasti Tiwari, Nikhil Sharma, Pritmohinder S. Gill, Peter Igarashi, C. Ronald Kahn, James B. Wade, and Carolyn M. A. Ecelbarger

Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor
PNAS 2008 105: 6469-6474; published online on April 18, 2008, 10.1073/pnas.0711283105 [Abstract] [Full Text] [Figures Only] [PDF]  

Plant Biology

David L. Lentz, Mary DeLand Pohl, José Luis Alvarado, Somayeh Tarighat, and Robert Bye

Sunflower (Helianthus annuus L.) as a pre-Columbian domesticate in Mexico
PNAS 2008 105: 6232-6237; published online on April 28, 2008, 10.1073/pnas.0711760105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Timothy K. Eitas, Zachary L. Nimchuk, and Jeffery L. Dangl Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by the Pseudomonas syringae effector AvrB PNAS 2008 105: 6475-6480; published online on April 18, 2008, 10.1073/pnas.0802157105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Claire Pujol, Marc Bailly, Daniel Kern, Laurence Maréchal-Drouard, Hubert Becker, and Anne-Marie Duchêne

Dual-targeted tRNA-dependent amidotransferase ensures both mitochondrial and chloroplastic Gln-tRNA^Gln synthesis in plants
PNAS 2008 105: 6481-6485; published online on April 25, 2008, 10.1073/pnas.0712299105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

J. Armando Casas-Mollano, Byeong-ryool Jeong, Jianping Xu, Hideaki Moriyama, and Heriberto Cerutti

The MUT9p kinase phosphorylates histone H3 threonine 3 and is necessary for heritable epigenetic silencing in Chlamydomonas
PNAS 2008 105: 6486-6491; published online on April 17, 2008, 10.1073/pnas.0711310105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Psychology

Johahn Leung, David Alais, and Simon Carlile

Compression of auditory space during rapid head turns
PNAS 2008 105: 6492-6497; published online on April 21, 2008, 10.1073/pnas.0710837105 [Abstract] [Full Text] [Figures Only] [PDF]  

Sustainability Science

Michael Bode, Kerrie A. Wilson, Thomas M. Brooks, Will R. Turner, Russell A. Mittermeier, Marissa F. McBride, Emma C. Underwood, and Hugh P. Possingham

Cost-effective global conservation spending is robust to taxonomic group
PNAS 2008 105: 6498-6501; published online on April 14, 2008, 10.1073/pnas.0710705105 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 6505

CORRECTIONS

Correction for Yu et al., Nucleoprotein structure of the CD4 locus: Implications for the mechanisms underlying CD4 regulation during T cell development [Full Text] [Figures Only] [PDF]