This Week in PNAS

Commentary

  • Commentary:
    • Richard D. Kolodner,
    • Marc L. Mendillo,
    • and Christopher D. Putnam

    Coupling distant sites in DNA during DNA mismatch repair

    PNAS 2007 104:12953-12954; published ahead of print July 30, 2007, doi:10.1073/pnas.0705698104
    • See companion article on page 12709 in issue 31 of volume 104

Perspective

  • Perspective - Nobel Lecture:
    • Roger D. Kornberg

    The molecular basis of eukaryotic transcription

    PNAS 2007 104:12955-12961; published ahead of print August 1, 2007, doi:10.1073/pnas.0704138104

Physical Sciences

Applied Physical Sciences

  • Physical Sciences - Applied Physical Sciences:
    • Feng Ye,
    • Wolfgang Sprengel,
    • Rainer K. Wunderlich,
    • Hans-Jörg Fecht,
    • and Hans-Eckhardt Schaefer

    From the Cover: Reversible atomic processes as basic mechanisms of the glass transition

    PNAS 2007 104:12962-12965; published ahead of print July 30, 2007, doi:10.1073/pnas.0705221104
  • Physical Sciences - Applied Physical Sciences - Biological Sciences - Applied Biological Sciences:
    • David B. Rozema,
    • David L. Lewis,
    • Darren H. Wakefield,
    • So C. Wong,
    • Jason J. Klein,
    • Paula L. Roesch,
    • Stephanie L. Bertin,
    • Tom W. Reppen,
    • Qili Chu,
    • Andrei V. Blokhin,
    • James E. Hagstrom,
    • and Jon A. Wolff

    Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

    PNAS 2007 104:12982-12987; published ahead of print July 24, 2007, doi:10.1073/pnas.0703778104

Chemistry

Geology

  • Physical Sciences - Geology:
    • Matthew E. Clapham
    • and David J. Bottjer

    From the Cover: Prolonged Permian–Triassic ecological crisis recorded by molluscan dominance in Late Permian offshore assemblages

    PNAS 2007 104:12971-12975; published ahead of print July 30, 2007, doi:10.1073/pnas.0705280104

Social Sciences

Psychology

  • Social Sciences - Psychology - Biological Sciences - Evolution:
    • Keith Jensen,
    • Josep Call,
    • and Michael Tomasello

    Chimpanzees are vengeful but not spiteful

    PNAS 2007 104:13046-13050; published ahead of print July 20, 2007, doi:10.1073/pnas.0705555104
    • See commentary article on page 13537 in issue 34 of volume 104

Biological Sciences

Agricultural Sciences

  • Biological Sciences - Agricultural Sciences:
    • Hans T. Alborn,
    • Trond V. Hansen,
    • Tappey H. Jones,
    • Derrick C. Bennett,
    • James H. Tumlinson,
    • Eric A. Schmelz,
    • and Peter E. A. Teal

    Disulfooxy fatty acids from the American bird grasshopper Schistocerca americana , elicitors of plant volatiles

    PNAS 2007 104:12976-12981; published ahead of print July 30, 2007, doi:10.1073/pnas.0705947104

Applied Biological Sciences

  • Physical Sciences - Applied Physical Sciences - Biological Sciences - Applied Biological Sciences:
    • David B. Rozema,
    • David L. Lewis,
    • Darren H. Wakefield,
    • So C. Wong,
    • Jason J. Klein,
    • Paula L. Roesch,
    • Stephanie L. Bertin,
    • Tom W. Reppen,
    • Qili Chu,
    • Andrei V. Blokhin,
    • James E. Hagstrom,
    • and Jon A. Wolff

    Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

    PNAS 2007 104:12982-12987; published ahead of print July 24, 2007, doi:10.1073/pnas.0703778104
  • Biological Sciences - Applied Biological Sciences:
    • Paloma H. Giangrande,
    • JianXin Zhang,
    • Alice Tanner,
    • Andrea D. Eckhart,
    • Rachel E. Rempel,
    • Eran R. Andrechek,
    • Juliana M. Layzer,
    • Janelle R. Keys,
    • Per-Otto Hagen,
    • Joseph R. Nevins,
    • Walter J. Koch,
    • and Bruce A. Sullenger

    Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia

    PNAS 2007 104:12988-12993; published ahead of print July 25, 2007, doi:10.1073/pnas.0704754104
  • Biological Sciences - Applied Biological Sciences:
    • Andreas Zumbuehl,
    • Lino Ferreira,
    • Duncan Kuhn,
    • Anna Astashkina,
    • Lisa Long,
    • Yoon Yeo,
    • Tiffany Iaconis,
    • Mahmoud Ghannoum,
    • Gerald R. Fink,
    • Robert Langer,
    • and Daniel S. Kohane

    Antifungal hydrogels

    PNAS 2007 104:12994-12998; published ahead of print July 30, 2007, doi:10.1073/pnas.0705250104

Biochemistry

  • Biological Sciences - Biochemistry:
    • Martin J. Gallagher,
    • Li Ding,
    • Ankit Maheshwari,
    • and Robert L. Macdonald

    The GABA A receptor α1 subunit epilepsy mutation A322D inhibits transmembrane helix formation and causes proteasomal degradation

    PNAS 2007 104:12999-13004; published ahead of print August 1, 2007, doi:10.1073/pnas.0700163104
  • Biological Sciences - Biochemistry:
    • Martin Andresen,
    • Andre C. Stiel,
    • Simon Trowitzsch,
    • Gert Weber,
    • Christian Eggeling,
    • Markus C. Wahl,
    • Stefan W. Hell,
    • and Stefan Jakobs

    Structural basis for reversible photoswitching in Dronpa

    PNAS 2007 104:13005-13009; published ahead of print July 23, 2007, doi:10.1073/pnas.0700629104
  • Biological Sciences - Biochemistry:
    • Youngsoo Jun
    • and William Wickner

    Assays of vacuole fusion resolve the stages of docking, lipid mixing, and content mixing

    PNAS 2007 104:13010-13015; published ahead of print July 30, 2007, doi:10.1073/pnas.0700970104
  • Biological Sciences - Biochemistry:
    • Boris Breiner,
    • Jörg C. Schlatterer,
    • Igor V. Alabugin,
    • Serguei V. Kovalenko,
    • and Nancy L. Greenbaum

    DNA damage-site recognition by lysine conjugates

    PNAS 2007 104:13016-13021; published ahead of print July 30, 2007, doi:10.1073/pnas.0705701104

Biophysics

  • Biological Sciences - Biophysics:
    • Elhanan Magidovich,
    • Irit Orr,
    • Deborah Fass,
    • Uri Abdu,
    • and Ofer Yifrach

    Intrinsic disorder in the C-terminal domain of the Shaker voltage-activated K + channel modulates its interaction with scaffold proteins

    PNAS 2007 104:13022-13027; published ahead of print July 31, 2007, doi:10.1073/pnas.0704059104

Cell Biology

  • Biological Sciences - Cell Biology:
    • Chi-Hwa Wu,
    • Jan van Riggelen,
    • Alper Yetil,
    • Alice C. Fan,
    • Pavan Bachireddy,
    • and Dean W. Felsher

    Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

    PNAS 2007 104:13028-13033; published ahead of print July 30, 2007, doi:10.1073/pnas.0701953104
  • Biological Sciences - Cell Biology:
    • Santanu K. Ghosh,
    • Sujata Hajra,
    • and Makkuni Jayaram

    Faithful segregation of the multicopy yeast plasmid through cohesin-mediated recognition of sisters

    PNAS 2007 104:13034-13039; published ahead of print August 1, 2007, doi:10.1073/pnas.0702996104
  • Biological Sciences - Cell Biology:
    • Guangwei Wei,
    • Stephen Ku,
    • Gene K. Ma,
    • Shin'ichi Saito,
    • Amy A. Tang,
    • Jiasheng Zhang,
    • Jian-Hua Mao,
    • Ettore Appella,
    • Allan Balmain,
    • and Eric J. Huang

    HIPK2 represses β-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis

    PNAS 2007 104:13040-13045; published ahead of print July 31, 2007, doi:10.1073/pnas.0703213104
    Open Access Article

Evolution

  • Social Sciences - Psychology - Biological Sciences - Evolution:
    • Keith Jensen,
    • Josep Call,
    • and Michael Tomasello

    Chimpanzees are vengeful but not spiteful

    PNAS 2007 104:13046-13050; published ahead of print July 20, 2007, doi:10.1073/pnas.0705555104
    • See commentary article on page 13537 in issue 34 of volume 104
  • Biological Sciences - Evolution:
    • Frederic Mery,
    • Amsale T. Belay,
    • Anthony K.-C. So,
    • Marla B. Sokolowski,
    • and Tadeusz J. Kawecki

    From the Cover: Natural polymorphism affecting learning and memory in Drosophila

    PNAS 2007 104:13051-13055; published ahead of print July 19, 2007, doi:10.1073/pnas.0702923104
    • See commentary article on page 13539 in issue 34 of volume 104

Genetics

  • Biological Sciences - Genetics:
    • Dana C. Dolinoy,
    • Dale Huang,
    • and Randy L. Jirtle

    Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development

    PNAS 2007 104:13056-13061; published ahead of print August 1, 2007, doi:10.1073/pnas.0703739104
  • Biological Sciences - Genetics:
    • Daniele Grazziotin Soares,
    • Alexandre E. Escargueil,
    • Virginie Poindessous,
    • Alain Sarasin,
    • Aimery de Gramont,
    • Diego Bonatto,
    • João Antonio Pêgas Henriques,
    • and Annette K. Larsen

    From the Cover: Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743

    PNAS 2007 104:13062-13067; published ahead of print July 26, 2007, doi:10.1073/pnas.0609877104
  • Biological Sciences - Genetics:
    • Zhiyong Mao,
    • Andrei Seluanov,
    • Ying Jiang,
    • and Vera Gorbunova

    TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination

    PNAS 2007 104:13068-13073; published ahead of print August 1, 2007, doi:10.1073/pnas.0702410104

Immunology

  • Biological Sciences - Immunology:
    • Maria Koulmanda,
    • Ejona Budo,
    • Susan Bonner-Weir,
    • Andi Qipo,
    • Prabhakar Putheti,
    • Nicolas Degauque,
    • Hang Shi,
    • Zhigang Fan,
    • Jeffrey S. Flier,
    • Hugh Auchincloss, Jr.,
    • Xin Xiao Zheng,
    • and Terry B. Strom

    Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts

    PNAS 2007 104:13074-13079; published ahead of print August 1, 2007, doi:10.1073/pnas.0705863104
  • Biological Sciences - Immunology:
    • Luca Varani,
    • Alexander J. Bankovich,
    • Corey W. Liu,
    • Leremy A. Colf,
    • Lindsay L. Jones,
    • David M. Kranz,
    • Joseph D. Puglisi,
    • and K. Christopher Garcia

    Solution mapping of T cell receptor docking footprints on peptide-MHC

    PNAS 2007 104:13080-13085; published ahead of print August 1, 2007, doi:10.1073/pnas.0703702104

Medical Sciences

  • Biological Sciences - Medical Sciences:
    • Jae K. Lee,
    • Dmytro M. Havaleshko,
    • HyungJun Cho,
    • John N. Weinstein,
    • Eric P. Kaldjian,
    • John Karpovich,
    • Andrew Grimshaw,
    • and Dan Theodorescu

    A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery

    PNAS 2007 104:13086-13091; published ahead of print July 31, 2007, doi:10.1073/pnas.0610292104
  • Biological Sciences - Medical Sciences:
    • Aleksandra Franovic,
    • Lakshman Gunaratnam,
    • Karlene Smith,
    • Isabelle Robert,
    • David Patten,
    • and Stephen Lee

    Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer

    PNAS 2007 104:13092-13097; published ahead of print August 1, 2007, doi:10.1073/pnas.0702387104
  • Biological Sciences - Medical Sciences:
    • Agnes Coste,
    • Laurent Dubuquoy,
    • Romain Barnouin,
    • Jean-Sebastien Annicotte,
    • Benjamin Magnier,
    • Mario Notti,
    • Nadia Corazza,
    • Maria Cristina Antal,
    • Daniel Metzger,
    • Pierre Desreumaux,
    • Thomas Brunner,
    • Johan Auwerx,
    • and Kristina Schoonjans

    LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease

    PNAS 2007 104:13098-13103; published ahead of print August 1, 2007, doi:10.1073/pnas.0702440104
  • Biological Sciences - Medical Sciences:
    • Jinhui Wang,
    • Jing Xie,
    • Hui Lu,
    • Lingxia Chen,
    • Bernd Hauck,
    • Richard Jude Samulski,
    • and Weidong Xiao

    Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction

    PNAS 2007 104:13104-13109; published ahead of print July 30, 2007, doi:10.1073/pnas.0702778104
  • Biological Sciences - Medical Sciences:
    • Dong Sung An,
    • Robert E. Donahue,
    • Masakazu Kamata,
    • Betty Poon,
    • Mark Metzger,
    • Si-Hua Mao,
    • Aylin Bonifacino,
    • Allen E. Krouse,
    • Jean-Luc Darlix,
    • David Baltimore,
    • F. Xiao-Feng Qin,
    • and Irvin S. Y. Chen

    Stable reduction of CCR5 by RNAi through hematopoietic stem cell transplant in non-human primates

    PNAS 2007 104:13110-13115; published ahead of print August 1, 2007, doi:10.1073/pnas.0705474104
  • Biological Sciences - Medical Sciences:
    • Y. M. Dennis Lo,
    • Fiona M. F. Lun,
    • K. C. Allen Chan,
    • Nancy B. Y. Tsui,
    • Ka C. Chong,
    • Tze K. Lau,
    • Tak Y. Leung,
    • Benny C. Y. Zee,
    • Charles R. Cantor,
    • and Rossa W. K. Chiu

    From the Cover: Digital PCR for the molecular detection of fetal chromosomal aneuploidy

    PNAS 2007 104:13116-13121; published ahead of print July 30, 2007, doi:10.1073/pnas.0705765104
    Open Access Article
  • Biological Sciences - Medical Sciences:
    • Jacob Bock Axelsen,
    • Joseph Lotem,
    • Leo Sachs,
    • and Eytan Domany

    Genes overexpressed in different human solid cancers exhibit different tissue-specific expression profiles

    PNAS 2007 104:13122-13127; published ahead of print July 30, 2007, doi:10.1073/pnas.0705824104
  • Biological Sciences - Medical Sciences:
    • Bramanandam Manavathi,
    • Shaohua Peng,
    • Suresh K. Rayala,
    • Amjad H. Talukder,
    • Minhua H. Wang,
    • Rui-An Wang,
    • Seetharaman Balasenthil,
    • Neeraj Agarwal,
    • Laura J. Frishman,
    • and Rakesh Kumar

    Repression of Six3 by a corepressor regulates rhodopsin expression

    PNAS 2007 104:13128-13133; published ahead of print July 31, 2007, doi:10.1073/pnas.0705878104
  • Biological Sciences - Medical Sciences:
    • Przemyslaw Juszczynski,
    • Jing Ouyang,
    • Stefano Monti,
    • Scott J. Rodig,
    • Kunihiko Takeyama,
    • Jeremy Abramson,
    • Wen Chen,
    • Jeffery L. Kutok,
    • Gabriel A. Rabinovich,
    • and Margaret A. Shipp

    The AP1-dependent secretion of galectin-1 by Reed–Sternberg cells fosters immune privilege in classical Hodgkin lymphoma

    PNAS 2007 104:13134-13139; published ahead of print August 1, 2007, doi:10.1073/pnas.0706017104
    Open Access Article

Microbiology

  • Biological Sciences - Microbiology:
    • Erick Lin
    • and Patricia G. Spear

    Random linker-insertion mutagenesis to identify functional domains of herpes simplex virus type 1 glycoprotein B

    PNAS 2007 104:13140-13145; published ahead of print July 31, 2007, doi:10.1073/pnas.0705926104
  • Biological Sciences - Microbiology:
    • Sebastian Fraune
    • and Thomas C. G. Bosch

    Long-term maintenance of species-specific bacterial microbiota in the basal metazoan Hydra

    PNAS 2007 104:13146-13151; published ahead of print July 30, 2007, doi:10.1073/pnas.0703375104
    Open Access Article

Neuroscience

  • Biological Sciences - Neuroscience:
    • Pranab K. Mukherjee,
    • Victor L. Marcheselli,
    • Sebastian Barreiro,
    • Jane Hu,
    • Dean Bok,
    • and Nicolas G. Bazan

    Neurotrophins enhance retinal pigment epithelial cell survival through neuroprotectin D1 signaling

    PNAS 2007 104:13152-13157; published ahead of print August 1, 2007,