Commentaries

  • Commentary:
    • Anthony H. Dickenson,
    • Lucy A. Bee,
    • and Rie Suzuki

    Pains, gains, and midbrains

    PNAS 2005 102:17885-17886; published ahead of print December 5, 2005, doi:10.1073/pnas.0508494102
    • See companion article on page 18195 in issue 50 of volume 102
  • Commentary:
    • Venkatesan Sundaresan

    Control of seed size in plants

    PNAS 2005 102:17887-17888; published ahead of print December 5, 2005, doi:10.1073/pnas.0509021102
    • See companion article on page 17531 in issue 48 of volume 102
  • Commentary:
    • Albert R. La Spada

    Huntington's disease and neurogenesis: FGF-2 to the rescue?

    PNAS 2005 102:17889-17890; published ahead of print December 5, 2005, doi:10.1073/pnas.0509222102
    • See companion article on page 18189 in issue 50 of volume 102

In This Issue

Physical Sciences

Chemistry

  • Physical Sciences - Chemistry:
    • Andrzej L. Sobolewski,
    • Wolfgang Domcke,
    • and C. Hättig

    Tautomeric selectivity of the excited-state lifetime of guanine/cytosine base pairs: The role of electron-driven proton-transfer processes

    PNAS 2005 102:17903-17906; published ahead of print December 5, 2005, doi:10.1073/pnas.0504087102
  • Physical Sciences - Chemistry:
    • E. Charles H. Sykes,
    • Luis C. Fernández-Torres,
    • Sanjini U. Nanayakkara,
    • Brent A. Mantooth,
    • Ryan M. Nevin,
    • and Paul S. Weiss

    Observation and manipulation of subsurface hydride in Pd{111} and its effect on surface chemical, physical, and electronic properties

    PNAS 2005 102:17907-17911; published ahead of print December 1, 2005, doi:10.1073/pnas.0506657102
  • Physical Sciences - Chemistry - Biological Sciences - Physiology:
    • Briar R. Ertz-Berger,
    • Huamei He,
    • Candice Dowell,
    • Stephen M. Factor,
    • Todd E. Haim,
    • Sara Nunez,
    • Steven D. Schwartz,
    • Joanne S. Ingwall,
    • and Jil C. Tardiff

    Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice

    PNAS 2005 102:18219-18224; published ahead of print December 2, 2005, doi:10.1073/pnas.0509181102

Environmental Sciences

  • Physical Sciences - Environmental Sciences:
    • I. M. Held,
    • T. L. Delworth,
    • J. Lu,
    • K. L. Findell,
    • and T. R. Knutson

    Inaugural Article: Simulation of Sahel drought in the 20th and 21st centuries

    PNAS 2005 102:17891-17896; published ahead of print December 1, 2005, doi:10.1073/pnas.0509057102
    • See commentary article on page 2012 in issue 7 of volume 103
  • Physical Sciences - Environmental Sciences:
    • Max A. Moritz,
    • Marco E. Morais,
    • Lora A. Summerell,
    • J. M. Carlson,
    • and John Doyle

    From the Cover: Wildfires, complexity, and highly optimized tolerance

    PNAS 2005 102:17912-17917; published ahead of print December 6, 2005, doi:10.1073/pnas.0508985102

Geophysics

  • Physical Sciences - Geophysics:
    • S. Speziale,
    • A. Milner,
    • V. E. Lee,
    • S. M. Clark,
    • M. P. Pasternak,
    • and R. Jeanloz

    Iron spin transition in Earth's mantle

    PNAS 2005 102:17918-17922; published ahead of print December 5, 2005, doi:10.1073/pnas.0508919102

Biological Sciences

Agricultural Sciences

  • Biological Sciences - Agricultural Sciences:
    • David H. Baker

    Inaugural Article: Comparative nutrition and metabolism: Explication of open questions with emphasis on protein and amino acids

    PNAS 2005 102:17897-17902; published ahead of print December 2, 2005, doi:10.1073/pnas.0509317102
    • See commentary article on page 3020 in issue 9 of volume 103

Biochemistry

  • Biological Sciences - Biochemistry:
    • Masato Otsuka,
    • Takuya Matsumoto,
    • Riyo Morimoto,
    • Shigeo Arioka,
    • Hiroshi Omote,
    • and Yoshinori Moriyama

    From the Cover: A human transporter protein that mediates the final excretion step for toxic organic cations

    PNAS 2005 102:17923-17928; published ahead of print December 5, 2005, doi:10.1073/pnas.0506483102
  • Biological Sciences - Biochemistry:
    • Hiromi Imamura,
    • Mizuho Takeda,
    • Saeko Funamoto,
    • Katsuya Shimabukuro,
    • Masasuke Yoshida,
    • and Ken Yokoyama

    Rotation scheme of V 1 -motor is different from that of F 1 -motor

    PNAS 2005 102:17929-17933; published ahead of print December 5, 2005, doi:10.1073/pnas.0507764102
  • Biological Sciences - Biochemistry:
    • Lennart Randau,
    • Kate Calvin,
    • Michelle Hall,
    • Jing Yuan,
    • Mircea Podar,
    • Hong Li,
    • and Dieter Söll

    The heteromeric Nanoarchaeum equitans splicing endonuclease cleaves noncanonical bulge–helix–bulge motifs of joined tRNA halves

    PNAS 2005 102:17934-17939; published ahead of print December 5, 2005, doi:10.1073/pnas.0509197102
  • Biological Sciences - Biochemistry:
    • Noah Dephoure,
    • Russell W. Howson,
    • Justin D. Blethrow,
    • Kevan M. Shokat,
    • and Erin K. O'Shea

    Combining chemical genetics and proteomics to identify protein kinase substrates

    PNAS 2005 102:17940-17945; published ahead of print December 5, 2005, doi:10.1073/pnas.0509080102
  • Biological Sciences - Biochemistry:
    • Eduard Torrents,
    • Margareta Sahlin,
    • Daniele Biglino,
    • Astrid Gräslund,
    • and Britt-Marie Sjöberg

    Efficient growth inhibition of Bacillus anthracis by knocking out the ribonucleotide reductase tyrosyl radical

    PNAS 2005 102:17946-17951; published ahead of print December 1, 2005, doi:10.1073/pnas.0506410102
  • Biological Sciences - Biochemistry:
    • Baibaswata Nayak,
    • Ping Xie,
    • Shigeru Akagi,
    • Qiwei Yang,
    • Lin Sun,
    • Jun Wada,
    • Arun Thakur,
    • Farhad R. Danesh,
    • Sumant S. Chugh,
    • and Yashpal S. Kanwar

    Modulation of renal-specific oxidoreductase/ myo -inositol oxygenase by high-glucose ambience

    PNAS 2005 102:17952-17957; published ahead of print December 5, 2005, doi:10.1073/pnas.0509089102

Biophysics

  • Biological Sciences - Biophysics:
    • J. R. Simard,
    • P. A. Zunszain,
    • C.-E. Ha,
    • J. S. Yang,
    • N. V. Bhagavan,
    • I. Petitpas,
    • S. Curry,
    • and J. A. Hamilton

    Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy

    PNAS 2005 102:17958-17963; published ahead of print December 5, 2005, doi:10.1073/pnas.0506440102
  • Biological Sciences - Biophysics:
    • Zhengshuang Shi,
    • Kang Chen,
    • Zhigang Liu,
    • Angela Ng,
    • W. Clay Bracken,
    • and Neville R. Kallenbach

    Polyproline II propensities from GGXGG peptides reveal an anticorrelation with β-sheet scales

    PNAS 2005 102:17964-17968; published ahead of print December 5, 2005, doi:10.1073/pnas.0507124102
  • Biological Sciences - Biophysics:
    • Gang Lu,
    • James M. Westbrooks,
    • Amy L. Davidson,
    • and Jue Chen

    ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation

    PNAS 2005 102:17969-17974; published ahead of print December 2, 2005, doi:10.1073/pnas.0506039102

Cell Biology

  • Biological Sciences - Cell Biology:
    • Lisa J. Pagliari,
    • Tomomi Kuwana,
    • Christine Bonzon,
    • Donald D. Newmeyer,
    • Shine Tu,
    • Helen M. Beere,
    • and Douglas R. Green

    The multidomain proapoptotic molecules Bax and Bak are directly activated by heat

    PNAS 2005 102:17975-17980; published ahead of print December 5, 2005, doi:10.1073/pnas.0506712102
  • Biological Sciences - Cell Biology:
    • Tomasz J. Proszynski,
    • Robin W. Klemm,
    • Maike Gravert,
    • Peggy P. Hsu,
    • Yvonne Gloor,
    • Jan Wagner,
    • Karol Kozak,
    • Hannes Grabner,
    • Karen Walzer,
    • Michel Bagnat,
    • Kai Simons,
    • and Christiane Walch-Solimena

    A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast

    PNAS 2005 102:17981-17986; published ahead of print December 5, 2005, doi:10.1073/pnas.0509107102
  • Biological Sciences - Cell Biology:
    • Cary D. Austin,
    • Xiaohui Wen,
    • Lewis Gazzard,
    • Christopher Nelson,
    • Richard H. Scheller,
    • and Suzie J. Scales

    Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody–drug conjugates

    PNAS 2005 102:17987-17992; published ahead of print December 1, 2005, doi:10.1073/pnas.0509035102
  • Biological Sciences - Cell Biology:
    • Aleksandra Trifunovic,
    • Anna Hansson,
    • Anna Wredenberg,
    • Anja T. Rovio,
    • Eric Dufour,
    • Ivan Khvorostov,
    • Johannes N. Spelbrink,
    • Rolf Wibom,
    • Howard T. Jacobs,
    • and Nils-Göran Larsson

    From the Cover: Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

    PNAS 2005 102:17993-17998; published ahead of print December 6, 2005, doi:10.1073/pnas.0508886102
    • See commentary article on page 18769 in issue 52 of volume 102
  • Biological Sciences - Cell Biology:
    • Takehiro Sato,
    • Masatoshi Esaki,
    • Julio M. Fernandez,
    • and Toshiya Endo

    Comparison of the protein-unfolding pathways between mitochondrial protein import and atomic-force microscopy measurements

    PNAS 2005 102:17999-18004; published ahead of print December 2, 2005, doi:10.1073/pnas.0504495102
  • Biological Sciences - Cell Biology:
    • Ashwini Jambhekar,
    • Kimberly McDermott,
    • Katherine Sorber,
    • Kelly A. Shepard,
    • Ronald D. Vale,
    • Peter A. Takizawa,
    • and Joseph L. DeRisi

    Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae

    PNAS 2005 102:18005-18010; published ahead of print December 2, 2005, doi:10.1073/pnas.0509229102

Developmental Biology

  • Biological Sciences - Developmental Biology:
    • May-yun Wang,
    • Lelio Orci,
    • Mariella Ravazzola,
    • and Roger H. Unger

    Fat storage in adipocytes requires inactivation of leptin's paracrine activity: Implications for treatment of human obesity

    PNAS 2005 102:18011-18016; published ahead of print December 2, 2005, doi:10.1073/pnas.0509001102
  • Biological Sciences - Developmental Biology:
    • A. Aziz Aboobaker,
    • Pavel Tomancak,
    • Nipam Patel,
    • Gerald M. Rubin,
    • and Eric C. Lai

    Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development

    PNAS 2005 102:18017-18022; published ahead of print December 5, 2005, doi:10.1073/pnas.0508823102
  • Biological Sciences - Developmental Biology:
    • Tatsuya Kobayashi,
    • Karen M. Lyons,
    • Andrew P. McMahon,
    • and Henry M. Kronenberg

    BMP signaling stimulates cellular differentiation at multiple steps during cartilage development

    PNAS 2005 102:18023-18027; published ahead of print December 1, 2005, doi:10.1073/pnas.0503617102
  • Biological Sciences - Developmental Biology:
    • Ekyune Kim,
    • Daichi Baba,
    • Masanori Kimura,
    • Misuzu Yamashita,
    • Shin-ichi Kashiwabara,
    • and Tadashi Baba

    Identification of a hyaluronidase, Hyal5, involved in penetration of mouse sperm through cumulus mass

    PNAS 2005 102:18028-18033; published ahead of print December 5, 2005, doi:10.1073/pnas.0506825102
  • Biological Sciences - Developmental Biology:
    • Masao Murakami,
    • Masayo Nakagawa,
    • Eric N. Olson,
    • and Osamu Nakagawa

    A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt–Oram syndrome

    PNAS 2005 102:18034-18039; published ahead of print December 6, 2005, doi:10.1073/pnas.0509109102

Ecology

  • Biological Sciences - Ecology:
    • Sergey Gavrilets
    • and Aaron Vose

    Dynamic patterns of adaptive radiation

    PNAS 2005 102:18040-18045; published ahead of print December 5, 2005, doi:10.1073/pnas.0506330102
  • Biological Sciences - Ecology:
    • Sergio A. Navarrete,
    • Evie A. Wieters,
    • Bernardo R. Broitman,
    • and Juan Carlos Castilla

    Scales of benthic–pelagic coupling and the intensity of species interactions: From recruitment limitation to top-down control

    PNAS 2005 102:18046-18051; published ahead of print December 6, 2005, doi:10.1073/pnas.0509119102
  • Biological Sciences - Ecology:
    • Richard J. Norby,
    • Evan H. DeLucia,
    • Birgit Gielen,
    • Carlo Calfapietra,
    • Christian P. Giardina,
    • John S. King,
    • Joanne Ledford,
    • Heather R. McCarthy,
    • David J. P. Moore,
    • Reinhart Ceulemans,
    • Paolo De Angelis,
    • Adrien C. Finzi,
    • David F. Karnosky,
    • Mark E. Kubiske,
    • Martin Lukac,
    • Kurt S. Pregitzer,
    • Giuseppe E. Scarascia-Mugnozza,
    • William H. Schlesinger,
    • and Ram Oren

    Forest response to elevated CO 2 is conserved across a broad range of productivity

    PNAS 2005 102:18052-18056; published ahead of print December 5, 2005, doi:10.1073/pnas.0509478102

Evolution

  • Biological Sciences - Evolution:
    • David C. Lahti

    Evolution of bird eggs in the absence of cuckoo parasitism

    PNAS 2005 102:18057-18062; published ahead of print December 2, 2005, doi:10.1073/pnas.0508930102
  • Biological Sciences - Evolution:
    • Kazuhiko Kawasaki,
    • Tohru Suzuki,
    • and Kenneth M. Weiss

    Phenogenetic drift in evolution: The changing genetic basis of vertebrate teeth

    PNAS 2005 102:18063-18068; published ahead of print December 6, 2005, doi:10.1073/pnas.0509263102

Genetics

  • Biological Sciences - Genetics:
    • Eliane El Achkar,
    • Michelle Gerbault-Seureau,
    • Martine Muleris,
    • Bernard Dutrillaux,
    • and Michelle Debatisse

    Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites

    PNAS 2005 102:18069-18074; published ahead of print December 5, 2005, doi:10.1073/pnas.0506497102
  • Biological Sciences - Genetics:
    • Suk-Hee Lee,
    • Masahiko Oshige,
    • Stephen T. Durant,
    • Kanwaldeep Kaur Rasila,
    • Elizabeth A. Williamson,
    • Heather Ramsey,
    • Lori Kwan,
    • Jac A. Nickoloff,
    • and Robert Hromas

    The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair

    PNAS 2005 102:18075-18080; published ahead of print December 6, 2005, doi:10.1073/pnas.0503676102
  • Biological Sciences - Genetics:
    • Nadia Felli,
    • Laura Fontana,
    • Elvira Pelosi,
    • Rosanna Botta,
    • Desirée Bonci,
    • Francesco Facchiano,
    • Francesca Liuzzi,
    • Valentina Lulli,
    • Ornella Morsilli,
    • Simona Santoro,
    • Mauro Valtieri,
    • George Adrian Calin,
    • Chang-Gong Liu,
    • Antonio Sorrentino,
    • Carlo M. Croce,
    • and Cesare Peschle

    MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation

    PNAS 2005 102:18081-18086; published ahead of print December 5, 2005, doi:10.1073/pnas.0506216102
  • Biological Sciences - Genetics:
    • Lyubov A. Lebedeva,
    • Elena N. Nabirochkina,
    • Mariya M. Kurshakova,
    • Flavie Robert,
    • Aleksey N. Krasnov,
    • Mihail B. Evgen'ev,
    • James T. Kadonaga,
    • Sofia G. Georgieva,
    • and Làszlò Tora

    Occupancy of the Drosophila hsp70 promoter by a subset of basal transcription factors diminishes upon transcriptional activation

    PNAS 2005 102:18087-18092; published ahead of print December 5, 2005, doi:10.1073/pnas.0509063102