Commentaries

  • Commentary:
    • Eric C. Freundt
    • and Michael J. Lenardo

    Interfering with interferons: Hepatitis C virus counters innate immunity

    PNAS 2005 102:17539-17540; published ahead of print November 28, 2005, doi:10.1073/pnas.0509221102
    • See companion article on page 17717 in issue 49 of volume 102
  • Commentary:
    • Raphael Mechoulam
    • and Dale G. Deutsch

    Toward an anandamide transporter

    PNAS 2005 102:17541-17542; published ahead of print November 28, 2005, doi:10.1073/pnas.0508644102
    • See companion article on page 17852 in issue 49 of volume 102
  • Commentary:
    • Christina Marchetti Bradley
    • and Robert Craigie

    Seeing is believing: Structure of the catalytic domain of HIV-1 integrase in complex with human LEDGF/p75

    PNAS 2005 102:17543-17544; published ahead of print November 28, 2005, doi:10.1073/pnas.0509078102
    • See companion article on page 17308 in issue 48 of volume 102

In This Issue

Physical Sciences

Applied Mathematics

  • Physical Sciences - Applied Mathematics - Biological Sciences - Genetics:
    • Orly Alter
    • and Gene H. Golub

    Reconstructing the pathways of a cellular system from genome-scale signals by using matrix and tensor computations

    PNAS 2005 102:17559-17564; published ahead of print November 28, 2005, doi:10.1073/pnas.0509033102

Applied Physical Sciences

  • Physical Sciences - Applied Physical Sciences:
    • Michael Hofmann,
    • Christian Eggeling,
    • Stefan Jakobs,
    • and Stefan W. Hell

    Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins

    PNAS 2005 102:17565-17569; published ahead of print November 28, 2005, doi:10.1073/pnas.0506010102

Chemistry

  • Physical Sciences - Chemistry:
    • Thomas D. Perroud,
    • Michael P. Bokoch,
    • and Richard N. Zare

    Cytochrome c conformations resolved by the photon counting histogram: Watching the alkaline transition with single-molecule sensitivity

    PNAS 2005 102:17570-17575; published ahead of print November 28, 2005, doi:10.1073/pnas.0508975102

Social Sciences

Psychology

  • Social Sciences - Psychology:
    • Heidrun Bien,
    • Willem J. M. Levelt,
    • and R. Harald Baayen

    Frequency effects in compound production

    PNAS 2005 102:17876-17881; published ahead of print November 21, 2005, doi:10.1073/pnas.0508431102

Biological Sciences

Agricultural Sciences

  • Biological Sciences - Agricultural Sciences:
    • Sadie L. Smith,
    • Robin E. Everts,
    • X. Cindy Tian,
    • Fuliang Du,
    • Li-Ying Sung,
    • Sandra L. Rodriguez-Zas,
    • Byeong-Seon Jeong,
    • Jean-Paul Renard,
    • Harris A. Lewin,
    • and Xiangzhong Yang

    Global gene expression profiles reveal significant nuclear reprogramming by the blastocyst stage after cloning

    PNAS 2005 102:17582-17587; published ahead of print November 28, 2005, doi:10.1073/pnas.0508952102

Applied Biological Sciences

  • Biological Sciences - Applied Biological Sciences:
    • D. R. Cox,
    • Christl A. Donnelly,
    • F. John Bourne,
    • George Gettinby,
    • John P. McInerney,
    • W. Ivan Morrison,
    • and Rosie Woodroffe

    Simple model for tuberculosis in cattle and badgers

    PNAS 2005 102:17588-17593; published ahead of print November 23, 2005, doi:10.1073/pnas.0509003102

Biochemistry

  • Biological Sciences - Biochemistry:
    • Hyun-Eui Kim,
    • Fenghe Du,
    • Min Fang,
    • and Xiaodong Wang

    Inaugural Article: Formation of apoptosome is initiated by cytochrome c -induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1

    PNAS 2005 102:17545-17550; published ahead of print October 26, 2005, doi:10.1073/pnas.0507900102
    • See commentary article on page 7 in issue 1 of volume 103
  • Biological Sciences - Biochemistry:
    • Jason Perry,
    • Nancy Kleckner,
    • and G. Valentin Börner

    Bioinformatic analyses implicate the collaborating meiotic crossover/chiasma proteins Zip2, Zip3, and Spo22/Zip4 in ubiquitin labeling

    PNAS 2005 102:17594-17599; published ahead of print November 28, 2005, doi:10.1073/pnas.0508581102
  • Biological Sciences - Biochemistry:
    • Mikhail B. Shevtsov,
    • Yanling Chen,
    • Paul Gollnick,
    • and Alfred A. Antson

    Crystal structure of Bacillus subtilis anti-TRAP protein, an antagonist of TRAP/RNA interaction

    PNAS 2005 102:17600-17605; published ahead of print November 23, 2005, doi:10.1073/pnas.0508728102
  • Biological Sciences - Biochemistry:
    • Myung Hee Kim,
    • Won-Chan Choi,
    • Hye Ok Kang,
    • Jong Suk Lee,
    • Beom Sik Kang,
    • Kyung-Jin Kim,
    • Zygmunt S. Derewenda,
    • Tae-Kwang Oh,
    • Choong Hwan Lee,
    • and Jung-Kee Lee

    The molecular structure and catalytic mechanism of a quorum-quenching N-acyl-L-homoserine lactone hydrolase

    PNAS 2005 102:17606-17611; published ahead of print November 28, 2005, doi:10.1073/pnas.0504996102
  • Biological Sciences - Biochemistry:
    • Kaiyu Ma,
    • Dmitry Temiakov,
    • Michael Anikin,
    • and William T. McAllister

    Probing conformational changes in T7 RNA polymerase during initiation and termination by using engineered disulfide linkages

    PNAS 2005 102:17612-17617; published ahead of print November 21, 2005, doi:10.1073/pnas.0508865102

Biophysics

  • Biological Sciences - Biophysics:
    • Oren Levy,
    • Jerod L. Ptacin,
    • Paul J. Pease,
    • Jeff Gore,
    • Michael B. Eisen,
    • Carlos Bustamante,
    • and Nicholas R. Cozzarelli

    Identification of oligonucleotide sequences that direct the movement of the Escherichia coli FtsK translocase

    PNAS 2005 102:17618-17623; published ahead of print November 21, 2005, doi:10.1073/pnas.0508932102
  • Biological Sciences - Biophysics:
    • Lina Salomonsson,
    • Kristina Faxén,
    • Pia Ädelroth,
    • and Peter Brzezinski

    The timing of proton migration in membrane-reconstituted cytochrome c oxidase

    PNAS 2005 102:17624-17629; published ahead of print November 23, 2005, doi:10.1073/pnas.0505431102
  • Biological Sciences - Biophysics:
    • Lizhi Gao,
    • Xianqiang Mi,
    • Vesa Paajanen,
    • Kun Wang,
    • and Zheng Fan

    From the Cover: Activation-coupled inactivation in the bacterial potassium channel KcsA

    PNAS 2005 102:17630-17635; published ahead of print November 21, 2005, doi:10.1073/pnas.0505158102
  • Biological Sciences - Biophysics:
    • Ming Li,
    • Hemali P. Phatnani,
    • Ziqiang Guan,
    • Harvey Sage,
    • Arno L. Greenleaf,
    • and Pei Zhou

    Solution structure of the Set2–Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1

    PNAS 2005 102:17636-17641; published ahead of print November 28, 2005, doi:10.1073/pnas.0506350102
  • Biological Sciences - Biophysics:
    • Leonor Saiz,
    • J. Miguel Rubi,
    • and Jose M. G. Vilar

    Inferring the in vivo looping properties of DNA

    PNAS 2005 102:17642-17645; published ahead of print November 22, 2005, doi:10.1073/pnas.0505693102
  • Biological Sciences - Biophysics:
    • Zimei Bu,
    • Ralf Biehl,
    • Michael Monkenbusch,
    • Dieter Richter,
    • and David J. E. Callaway

    Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy

    PNAS 2005 102:17646-17651; published ahead of print November 23, 2005, doi:10.1073/pnas.0503388102
  • Biological Sciences - Biophysics:
    • Nicola L. Smith,
    • Edward J. Taylor,
    • Anna-Marie Lindsay,
    • Simon J. Charnock,
    • Johan P. Turkenburg,
    • Eleanor J. Dodson,
    • Gideon J. Davies,
    • and Gary W. Black

    Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded β-helix

    PNAS 2005 102:17652-17657; published ahead of print November 28, 2005, doi:10.1073/pnas.0504782102

Cell Biology

Developmental Biology

  • Biological Sciences - Developmental Biology:
    • Ainhoa Pérez-Garijo,
    • Francisco A. Martín,
    • Gary Struhl,
    • and Ginés Morata

    Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila

    PNAS 2005 102:17664-17669; published ahead of print November 28, 2005, doi:10.1073/pnas.0508966102

Evolution

  • Biological Sciences - Evolution:
    • Piotr Sliwa
    • and Ryszard Korona

    Loss of dispensable genes is not adaptive in yeast

    PNAS 2005 102:17670-17674; published ahead of print November 28, 2005, doi:10.1073/pnas.0505517102

Genetics

  • Physical Sciences - Applied Mathematics - Biological Sciences - Genetics:
    • Orly Alter
    • and Gene H. Golub

    Reconstructing the pathways of a cellular system from genome-scale signals by using matrix and tensor computations

    PNAS 2005 102:17559-17564; published ahead of print November 28, 2005, doi:10.1073/pnas.0509033102
  • Biological Sciences - Genetics:
    • Barrett C. Foat,
    • S. Sean Houshmandi,
    • Wendy M. Olivas,
    • and Harmen J. Bussemaker

    Profiling condition-specific, genome-wide regulation of mRNA stability in yeast

    PNAS 2005 102:17675-17680; published ahead of print November 29, 2005, doi:10.1073/pnas.0503803102
  • Biological Sciences - Genetics:
    • Peter Ruoff,
    • Jennifer J. Loros,
    • and Jay C. Dunlap

    The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock

    PNAS 2005 102:17681-17686; published ahead of print November 28, 2005, doi:10.1073/pnas.0505137102
  • Biological Sciences - Genetics:
    • Henna Tyynismaa,
    • Katja Peltola Mjosund,
    • Sjoerd Wanrooij,
    • Ilse Lappalainen,
    • Emil Ylikallio,
    • Anu Jalanko,
    • Johannes N. Spelbrink,
    • Anders Paetau,
    • and Anu Suomalainen

    Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

    PNAS 2005 102:17687-17692; published ahead of print November 21, 2005, doi:10.1073/pnas.0505551102
  • Biological Sciences - Genetics:
    • David C. Grainger,
    • Douglas Hurd,
    • Marcus Harrison,
    • Jolyon Holdstock,
    • and Stephen J. W. Busby

    Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome

    PNAS 2005 102:17693-17698; published ahead of print November 21, 2005, doi:10.1073/pnas.0506687102
  • Biological Sciences - Genetics:
    • Adam D. Langenbacher,
    • Yuan Dong,
    • Xiaodong Shu,
    • Jayoung Choi,
    • Debora A. Nicoll,
    • Joshua I. Goldhaber,
    • Kenneth D. Philipson,
    • and Jau-Nian Chen

    Mutation in sodium–calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish

    PNAS 2005 102:17699-17704; published ahead of print November 28, 2005, doi:10.1073/pnas.0502679102
  • Biological Sciences - Genetics:
    • A. M. Ebert,
    • G. L. Hume,
    • K. S. Warren,
    • N. P. Cook,
    • C. G. Burns,
    • M. A. Mohideen,
    • G. Siegal,
    • D. Yelon,
    • M. C. Fishman,
    • and D. M. Garrity

    Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts

    PNAS 2005 102:17705-17710; published ahead of print November 28, 2005, doi:10.1073/pnas.0502683102
  • Biological Sciences - Genetics:
    • Paul Auerbach,
    • Richard A. O. Bennett,
    • Elisabeth A. Bailey,
    • Hans E. Krokan,
    • and Bruce Demple

    Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA

    PNAS 2005 102:17711-17716; published ahead of print November 28, 2005, doi:10.1073/pnas.0504643102

Immunology

  • Biological Sciences - Immunology:
    • Xiao-Dong Li,
    • Lijun Sun,
    • Rashu B. Seth,
    • Gabriel Pineda,
    • and Zhijian J. Chen

    From the Cover: Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

    PNAS 2005 102:17717-17722; published ahead of print November 21, 2005, doi:10.1073/pnas.0508531102
    • See commentary article on page 17539 in issue 49 of volume 102
  • Biological Sciences - Immunology:
    • David H. Broide,
    • Toby Lawrence,
    • Taylor Doherty,
    • Jae Youn Cho,
    • Marina Miller,
    • Kirsti McElwain,
    • Shauna McElwain,
    • and Michael Karin

    Allergen-induced peribronchial fibrosis and mucus production mediated by IκB kinase β-dependent genes in airway epithelium

    PNAS 2005 102:17723-17728; published ahead of print November 29, 2005, doi:10.1073/pnas.0509235102
  • Biological Sciences - Immunology:
    • Shannon J. Turley,
    • Je-Wook Lee,
    • Nick Dutton-Swain,
    • Diane Mathis,
    • and Christophe Benoist

    Endocrine self and gut non-self intersect in the pancreatic lymph nodes

    PNAS 2005 102:17729-17733; published ahead of print November 29, 2005, doi:10.1073/pnas.0509006102

Medical Sciences

  • Biological Sciences - Medical Sciences:
    • Juan I. Young,
    • Eugene P. Hong,
    • John C. Castle,
    • Juan Crespo-Barreto,
    • Aaron B. Bowman,
    • Matthew F. Rose,
    • Dongcheul Kang,
    • Ron Richman,
    • Jason M. Johnson,
    • Susan Berget,
    • and Huda Y. Zoghbi

    Inaugural Article: Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2

    PNAS 2005 102:17551-17558; published ahead of print October 26, 2005, doi:10.1073/pnas.0507856102
    • See commentary article on page 3017 in issue 9 of volume 103
  • Biological Sciences - Medical Sciences:
    • Yasuyuki Amoh,
    • Lingna Li,
    • Raul Campillo,
    • Katsumasa Kawahara,
    • Kensei Katsuoka,
    • Sheldon Penman,
    • and Robert M. Hoffman

    Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves

    PNAS 2005 102:17734-17738; published ahead of print November 28, 2005, doi:10.1073/pnas.0508440102
  • Biological Sciences - Medical Sciences:
    • Jung Yeon Kim,
    • Simon Tavaré,
    • and Darryl Shibata

    Counting human somatic cell replications: Methylation mirrors endometrial stem cell divisions

    PNAS 2005 102:17739-17744; published ahead of print November 28, 2005, doi:10.1073/pnas.0503976102
  • Biological Sciences - Medical Sciences:
    • Michael S. Isakoff,
    • Courtney G. Sansam,
    • Pablo Tamayo,
    • Aravind Subramanian,
    • Julia A. Evans,
    • Christine M. Fillmore,
    • Xi Wang,
    • Jaclyn A. Biegel,
    • Scott L. Pomeroy,
    • Jill P. Mesirov,
    • and Charles W. M. Roberts

    Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation

    PNAS 2005 102:17745-17750; published ahead of print November 21, 2005, doi:10.1073/pnas.0509014102
  • Biological Sciences - Medical Sciences:
    • Gang Zheng,
    • Juan Chen,
    • Hui Li,