Commentary

  • Commentary:
    • Ralf Bartenschlager
    • and Thomas Pietschmann

    Efficient hepatitis C virus cell culture system: What a difference the host cell makes

    PNAS 2005 102:9739-9740; published ahead of print July 5, 2005, doi:10.1073/pnas.0504296102
    • See companion article on page 9294 in issue 26 of volume 102

In This Issue

From the Academy

  • From the Academy:
    • Bruce Alberts

    From the Academy: Editorial: Modeling attacks on the food supply

    PNAS 2005 102:9737-9738; published ahead of print June 28, 2005, doi:10.1073/pnas.0504944102

Physical Sciences

Chemistry

  • Physical Sciences - Chemistry:
    • Thomas A. Scott,
    • Curtis P. Berlinguette,
    • Richard H. Holm,
    • and Hong-Cai Zhou

    Initial synthesis and structure of an all-ferrous analogue of the fully reduced [Fe 4 S 4 ] 0 cluster of the nitrogenase iron protein

    PNAS 2005 102:9741-9744; published ahead of print June 28, 2005, doi:10.1073/pnas.0504258102
  • Physical Sciences - Chemistry - Biological Sciences - Genetics:
    • Marcel O. Vlad,
    • Stefan E. Szedlacsek,
    • Nader Pourmand,
    • L. Luca Cavalli-Sforza,
    • Peter Oefner,
    • and John Ross

    Fisher's theorems for multivariable, time- and space-dependent systems, with applications in population genetics and chemical kinetics

    PNAS 2005 102:9848-9853; published ahead of print June 30, 2005, doi:10.1073/pnas.0504073102

Engineering

  • Physical Sciences - Engineering:
    • Kashan A. Shaikh,
    • Kee Suk Ryu,
    • Edgar D. Goluch,
    • Jwa-Min Nam,
    • Juewen Liu,
    • C. Shad Thaxton,
    • Thomas N. Chiesl,
    • Annelise E. Barron,
    • Yi Lu,
    • Chad A. Mirkin,
    • and Chang Liu

    A modular microfluidic architecture for integrated biochemical analysis

    PNAS 2005 102:9745-9750; published ahead of print June 28, 2005, doi:10.1073/pnas.0504082102

Geophysics

  • Physical Sciences - Geophysics:
    • Wendy L. Mao,
    • Yue Meng,
    • Guoyin Shen,
    • Vitali B. Prakapenka,
    • Andrew J. Campbell,
    • Dion L. Heinz,
    • Jinfu Shu,
    • Razvan Caracas,
    • Ronald E. Cohen,
    • Yingwei Fei,
    • Russell J. Hemley,
    • and Ho-kwang Mao

    Iron-rich silicates in the Earth's D″ layer

    PNAS 2005 102:9751-9753; published ahead of print June 30, 2005, doi:10.1073/pnas.0503737102

Social Sciences

Social Sciences

  • Social Sciences - Social Sciences:
    • Lawrence M. Wein
    • and Yifan Liu

    Analyzing a bioterror attack on the food supply: The case of botulinum toxin in milk

    PNAS 2005 102:9984-9989; published ahead of print June 28, 2005, doi:10.1073/pnas.0408526102

Biological Sciences

Biochemistry

  • Biological Sciences - Biochemistry:
    • Mikael J. Lindberg,
    • Roberth Byström,
    • Niklas Boknäs,
    • Peter M. Andersen,
    • and Mikael Oliveberg

    Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants

    PNAS 2005 102:9754-9759; published ahead of print June 29, 2005, doi:10.1073/pnas.0501957102
  • Biological Sciences - Biochemistry:
    • Anna B. Gilg,
    • Jeremy C. Bearfield,
    • Claus Tittiger,
    • William H. Welch,
    • and Gary J. Blomquist

    Isolation and functional expression of an animal geranyl diphosphate synthase and its role in bark beetle pheromone biosynthesis

    PNAS 2005 102:9760-9765; published ahead of print June 27, 2005, doi:10.1073/pnas.0503277102
  • Biological Sciences - Biochemistry:
    • Qi-Qun Tang,
    • Mads Grønborg,
    • Haiyan Huang,
    • Jae-Woo Kim,
    • Tamara C. Otto,
    • Akhilesh Pandey,
    • and M. Daniel Lane

    Sequential phosphorylation of CCAAT enhancer-binding protein β by MAPK and glycogen synthase kinase 3β is required for adipogenesis

    PNAS 2005 102:9766-9771; published ahead of print June 28, 2005, doi:10.1073/pnas.0503891102
  • Biological Sciences - Biochemistry:
    • Kara R. Schmelzer,
    • Lukas Kubala,
    • John W. Newman,
    • In-Hae Kim,
    • Jason P. Eiserich,
    • and Bruce D. Hammock

    Soluble epoxide hydrolase is a therapeutic target for acute inflammation

    PNAS 2005 102:9772-9777; published ahead of print June 30, 2005, doi:10.1073/pnas.0503279102
  • Biological Sciences - Biochemistry:
    • Neal F. Lue,
    • Dimitry Bosoy,
    • Tara J. Moriarty,
    • Chantal Autexier,
    • Brian Altman,
    • and Siyang Leng

    Telomerase can act as a template- and RNA-independent terminal transferase

    PNAS 2005 102:9778-9783; published ahead of print June 30, 2005, doi:10.1073/pnas.0502252102
  • Biological Sciences - Biochemistry:
    • Kerstin Helmstaedt,
    • Axel Strittmatter,
    • William N. Lipscomb,
    • and Gerhard H. Braus

    From the Cover: Evolution of 3-deoxy- d - arabino -heptulosonate-7-phosphate synthase-encoding genes in the yeast Saccharomyces cerevisiae

    PNAS 2005 102:9784-9789; published ahead of print June 29, 2005, doi:10.1073/pnas.0504238102

Biophysics

  • Biological Sciences - Biophysics:
    • Thomas Heimburg
    • and Andrew D. Jackson

    On soliton propagation in biomembranes and nerves

    PNAS 2005 102:9790-9795; published ahead of print July 1, 2005, doi:10.1073/pnas.0503823102
  • Biological Sciences - Biophysics:
    • Y. M. Wang,
    • Jonas O. Tegenfeldt,
    • W. Reisner,
    • R. Riehn,
    • Xiao-Juan Guan,
    • Ling Guo,
    • Ido Golding,
    • Edward C. Cox,
    • James Sturm,
    • and Robert H. Austin

    Single-molecule studies of repressor–DNA interactions show long-range interactions

    PNAS 2005 102:9796-9801; published ahead of print June 30, 2005, doi:10.1073/pnas.0502917102

Cell Biology

  • Biological Sciences - Cell Biology:
    • Fred Schaufele,
    • Xavier Carbonell,
    • Martin Guerbadot,
    • Sabine Borngraeber,
    • Mark S. Chapman,
    • Aye Aye K. Ma,
    • Jeffrey N. Miner,
    • and Marc I. Diamond

    The structural basis of androgen receptor activation: Intramolecular and intermolecular amino–carboxy interactions

    PNAS 2005 102:9802-9807; published ahead of print July 1, 2005, doi:10.1073/pnas.0408819102
  • Biological Sciences - Cell Biology:
    • Konstantin Doubrovinski
    • and Martin Howard

    Stochastic model for Soj relocation dynamics in Bacillus subtilis

    PNAS 2005 102:9808-9813; published ahead of print July 5, 2005, doi:10.1073/pnas.0500529102
  • Biological Sciences - Cell Biology:
    • Sanna Lehtonen,
    • Jennifer J. Ryan,
    • Krystyna Kudlicka,
    • Noriaki Iino,
    • Huilin Zhou,
    • and Marilyn G. Farquhar

    Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and α-actinin are components of the nephrin multiprotein complex

    PNAS 2005 102:9814-9819; published ahead of print July 1, 2005, doi:10.1073/pnas.0504166102
  • Biological Sciences - Cell Biology:
    • Nicolas Prévost,
    • Donna S. Woulfe,
    • Hong Jiang,
    • Timothy J. Stalker,
    • Patrizia Marchese,
    • Zaverio M. Ruggeri,
    • and Lawrence F. Brass

    Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets

    PNAS 2005 102:9820-9825; published ahead of print July 1, 2005, doi:10.1073/pnas.0404065102

Ecology

  • Biological Sciences - Ecology:
    • Erik M. Rauch
    • and Yaneer Bar-Yam

    Estimating the total genetic diversity of a spatial field population from a sample and implications of its dependence on habitat area

    PNAS 2005 102:9826-9829; published ahead of print July 5, 2005, doi:10.1073/pnas.0408471102

Evolution

  • Biological Sciences - Evolution:
    • Jim R. Hughes,
    • Jan-Fang Cheng,
    • Nicki Ventress,
    • Shyam Prabhakar,
    • Kevin Clark,
    • Eduardo Anguita,
    • Marco De Gobbi,
    • Pieter de Jong,
    • Eddy Rubin,
    • and Douglas R. Higgs

    Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequences

    PNAS 2005 102:9830-9835; published ahead of print July 5, 2005, doi:10.1073/pnas.0503401102
  • Biological Sciences - Evolution:
    • Marie Touchon,
    • Samuel Nicolay,
    • Benjamin Audit,
    • Edward-Benedict Brodie of Brodie,
    • Yves d'Aubenton-Carafa,
    • Alain Arneodo,
    • and Claude Thermes

    Replication-associated strand asymmetries in mammalian genomes: Toward detection of replication origins

    PNAS 2005 102:9836-9841; published ahead of print June 28, 2005, doi:10.1073/pnas.0500577102

Genetics

  • Biological Sciences - Genetics:
    • S. Nasuda,
    • S. Hudakova,
    • I. Schubert,
    • A. Houben,
    • and T. R. Endo

    Stable barley chromosomes without centromeric repeats

    PNAS 2005 102:9842-9847; published ahead of print July 5, 2005, doi:10.1073/pnas.0504235102
  • Physical Sciences - Chemistry - Biological Sciences - Genetics:
    • Marcel O. Vlad,
    • Stefan E. Szedlacsek,
    • Nader Pourmand,
    • L. Luca Cavalli-Sforza,
    • Peter Oefner,
    • and John Ross

    Fisher's theorems for multivariable, time- and space-dependent systems, with applications in population genetics and chemical kinetics

    PNAS 2005 102:9848-9853; published ahead of print June 30, 2005, doi:10.1073/pnas.0504073102
  • Biological Sciences - Genetics:
    • April J. Schumacher,
    • Dwight V. Nissley,
    • and Reuben S. Harris

    APOBEC3G hypermutates genomic DNA and inhibits Ty1 retrotransposition in yeast

    PNAS 2005 102:9854-9859; published ahead of print July 6, 2005, doi:10.1073/pnas.0501694102

Immunology

  • Biological Sciences - Immunology:
    • Sumathi Sankaran,
    • Moraima Guadalupe,
    • Elizabeth Reay,
    • Michael D. George,
    • Jason Flamm,
    • Thomas Prindiville,
    • and Satya Dandekar

    Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors

    PNAS 2005 102:9860-9865; published ahead of print June 24, 2005, doi:10.1073/pnas.0503463102
  • Biological Sciences - Immunology:
    • Pilar Martin,
    • Ricardo Villares,
    • Sandra Rodriguez-Mascarenhas,
    • Angel Zaballos,
    • Michael Leitges,
    • Judit Kovac,
    • Irene Sizing,
    • Paul Rennert,
    • Gabriel Márquez,
    • Carlos Martínez-A,
    • María T. Diaz-Meco,
    • and Jorge Moscat

    Control of T helper 2 cell function and allergic airway inflammation by PKCζ

    PNAS 2005 102:9866-9871; published ahead of print June 29, 2005, doi:10.1073/pnas.0501202102
  • Biological Sciences - Immunology:
    • P'ng Loke,
    • Xingxing Zang,
    • Lisa Hsuan,
    • Rebecca Waitz,
    • Richard M. Locksley,
    • Judith E. Allen,
    • and James P. Allison

    Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection

    PNAS 2005 102:9872-9877; published ahead of print July 1, 2005, doi:10.1073/pnas.0503961102

Medical Sciences

  • Biological Sciences - Medical Sciences:
    • Dulal Panda,
    • K. Rathinasamy,
    • Manas K. Santra,
    • and Leslie Wilson

    From the Cover: Kinetic suppression of microtubule dynamic instability by griseofulvin: Implications for its possible use in the treatment of cancer

    PNAS 2005 102:9878-9883; published ahead of print June 28, 2005, doi:10.1073/pnas.0501821102
  • Biological Sciences - Medical Sciences:
    • Timothy R. Carlson,
    • Yibing Yan,
    • Xiaoqing Wu,
    • Michael T. Lam,
    • Gale L. Tang,
    • Levi J. Beverly,
    • Louis M. Messina,
    • Anthony J. Capobianco,
    • Zena Werb,
    • and Rong Wang

    Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

    PNAS 2005 102:9884-9889; published ahead of print June 30, 2005, doi:10.1073/pnas.0504391102
  • Biological Sciences - Medical Sciences:
    • Yuexing Zhang,
    • Xin-Wei Wang,
    • Danijela Jelovac,
    • Takeo Nakanishi,
    • Myoung-hee Yu,
    • Damilola Akinmade,
    • Olga Goloubeva,
    • Douglas D. Ross,
    • Angela Brodie,
    • and Anne W. Hamburger

    The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells

    PNAS 2005 102:9890-9895; published ahead of print June 30, 2005, doi:10.1073/pnas.0503829102
  • Biological Sciences - Medical Sciences:
    • Dongxiao Feng
    • and Yuet Wai Kan

    The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of β-like globin genes

    PNAS 2005 102:9896-9900; published ahead of print July 5, 2005, doi:10.1073/pnas.0502041102
  • Biological Sciences - Medical Sciences:
    • Joseph E. Ippolito,
    • Jian Xu,
    • Sanjay Jain,
    • Krista Moulder,
    • Steven Mennerick,
    • Jan R. Crowley,
    • R. Reid Townsend,
    • and Jeffrey I. Gordon

    An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers

    PNAS 2005 102:9901-9906; published ahead of print July 5, 2005, doi:10.1073/pnas.0500756102

Microbiology

  • Biological Sciences - Microbiology:
    • Sophie Laurent,
    • Han Chen,
    • Sylvie Bédu,
    • Fabio Ziarelli,
    • Ling Peng,
    • and Cheng-Cai Zhang

    From the Cover: Nonmetabolizable analogue of 2-oxoglutarate elicits heterocyst differentiation under repressive conditions in Anabaena sp. PCC 7120

    PNAS 2005 102:9907-9912; published ahead of print June 28, 2005, doi:10.1073/pnas.0502337102
  • Biological Sciences - Microbiology:
    • Stefan F. Wieland,
    • Angelina Eustaquio,
    • Christina Whitten-Bauer,
    • Bryan Boyd,
    • and Francis V. Chisari

    Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids

    PNAS 2005 102:9913-9917; published ahead of print July 1, 2005, doi:10.1073/pnas.0504273102
  • Biological Sciences - Microbiology:
    • Baoshan Zhang,
    • Sha Jin,
    • Jing Jin,
    • Feng Li,
    • and Ronald C. Montelaro

    A tumor necrosis factor receptor family protein serves as a cellular receptor for the macrophage-tropic equine lentivirus

    PNAS 2005 102:9918-9923; published ahead of print June 28, 2005, doi:10.1073/pnas.0501560102
  • Biological Sciences - Microbiology:
    • John-Demian Sauer,
    • Michael A. Bachman,
    • and Michele S. Swanson

    The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages

    PNAS 2005 102:9924-9929; published ahead of print July 5, 2005, doi:10.1073/pnas.0502767102
  • Biological Sciences - Microbiology:
    • Mark L. Urbanowski,
    • Guinevere L. Lykken,
    • and Timothy L. Yahr

    A secreted regulatory protein couples transcription to the secretory activity of the Pseudomonas aeruginosa type III secretion system

    PNAS 2005 102:9930-9935; published ahead of print June 28, 2005, doi:10.1073/pnas.0504405102

Neuroscience

  • Biological Sciences - Neuroscience:
    • Jianrong Li,
    • Olivier Baud,
    • Timothy Vartanian,
    • Joseph J. Volpe,
    • and Paul A. Rosenberg

    Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes

    PNAS 2005 102:9936-9941; published ahead of print July 5, 2005, doi:10.1073/pnas.0502552102