Commentaries

  • Commentary:
    • Gary J. Pielak

    A model of intracellular organization

    PNAS 2005 102:5901-5902; published ahead of print April 19, 2005, doi:10.1073/pnas.0501812102
    • See companion article on page 5920 in issue 17 of volume 102
  • Commentary:
    • Duane P. Grandgenett

    Symmetrical recognition of cellular DNA target sequences during retroviral integration

    PNAS 2005 102:5903-5904; published ahead of print April 19, 2005, doi:10.1073/pnas.0502045102
    • See companion article on page 6103 in issue 17 of volume 102

In This Issue

PNAS Classic Article

  • PNAS Classic Article:
    • Richard J. Roberts

    Perspective: How restriction enzymes became the workhorses of molecular biology

    PNAS 2005 102:5905-5908; published ahead of print April 19, 2005, doi:10.1073/pnas.0500923102
  • PNAS Classic Article:
    • Christen Brownlee

    Classics: Danna and Nathans: Restriction enzymes and the boon to modern molecular biology

    PNAS 2005 102:5909; published ahead of print April 19, 2005, doi:10.1073/pnas.0502760102

Biography

  • Biography:
    • Bijal Trivedi

    Inaugural Article: Biography of Kathryn V. Anderson

    PNAS 2005 102:5910-5912; published ahead of print April 19, 2005, doi:10.1073/pnas.0501900102
    • See commentary article on page 5913 in issue 17 of volume 102

Physical Sciences

Chemistry

  • Physical Sciences - Chemistry:
    • M. Scott Long,
    • Clinton D. Jones,
    • Marcus R. Helfrich,
    • Lauren K. Mangeney-Slavin,
    • and Christine D. Keating

    From the Cover: Dynamic microcompartmentation in synthetic cells

    PNAS 2005 102:5920-5925; published ahead of print March 23, 2005, doi:10.1073/pnas.0409333102
    • See commentary article on page 5901 in issue 17 of volume 102
  • Physical Sciences - Chemistry:
    • Nampally Sreenivasachary
    • and Jean-Marie Lehn

    Gelation-driven component selection in the generation of constitutional dynamic hydrogels based on guanine-quartet formation

    PNAS 2005 102:5938-5943; published ahead of print April 19, 2005, doi:10.1073/pnas.0501663102
  • Physical Sciences - Chemistry:
    • Robert M. McKinlay,
    • Gareth W. V. Cave,
    • and Jerry L. Atwood

    Supramolecular blueprint approach to metal-coordinated capsules

    PNAS 2005 102:5944-5948; published ahead of print April 14, 2005, doi:10.1073/pnas.0408113102

Mathematics

  • Physical Sciences - Mathematics:
    • Diego Córdoba,
    • Marco A. Fontelos,
    • Ana M. Mancho,
    • and Jose L. Rodrigo

    Evidence of singularities for a family of contour dynamics equations

    PNAS 2005 102:5949-5952; published ahead of print April 18, 2005, doi:10.1073/pnas.0501977102

Social Sciences

Anthropology

  • Social Sciences - Anthropology:
    • Todd Surovell,
    • Nicole Waguespack,
    • and P. Jeffrey Brantingham

    Global archaeological evidence for proboscidean overkill

    PNAS 2005 102:6231-6236; published ahead of print April 13, 2005, doi:10.1073/pnas.0501947102

Biological Sciences

Applied Biological Sciences

  • Biological Sciences - Applied Biological Sciences:
    • Benjamin G. Keselowsky,
    • David M. Collard,
    • and Andrés J. García

    Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation

    PNAS 2005 102:5953-5957; published ahead of print April 12, 2005, doi:10.1073/pnas.0407356102

Biochemistry

  • Biological Sciences - Biochemistry:
    • Jean Guillerez,
    • Pascal J. Lopez,
    • Florence Proux,
    • Hélène Launay,
    • and Marc Dreyfus

    A mutation in T7 RNA polymerase that facilitates promoter clearance

    PNAS 2005 102:5958-5963; published ahead of print April 14, 2005, doi:10.1073/pnas.0407141102
  • Biological Sciences - Biochemistry:
    • Rose A. Gubitosi-Klug,
    • David J. Mancuso,
    • and Richard W. Gross

    The human Kv1.1 channel is palmitoylated, modulating voltage sensing: Identification of a palmitoylation consensus sequence

    PNAS 2005 102:5964-5968; published ahead of print April 18, 2005, doi:10.1073/pnas.0501999102
  • Biological Sciences - Biochemistry:
    • Xinchun Shen,
    • C. Alexander Valencia,
    • Jack Szostak,
    • Biao Dong,
    • and Rihe Liu

    Scanning the human proteome for calmodulin-binding proteins

    PNAS 2005 102:5969-5974; published ahead of print April 19, 2005, doi:10.1073/pnas.0407928102
  • Biological Sciences - Biochemistry:
    • Florence Mousson,
    • Aurélie Lautrette,
    • Jean-Yves Thuret,
    • Morgane Agez,
    • Régis Courbeyrette,
    • Béatrice Amigues,
    • Emmanuelle Becker,
    • Jean-Michel Neumann,
    • Raphaël Guerois,
    • Carl Mann,
    • and Françoise Ochsenbein

    Structural basis for the interaction of Asf1 with histone H3 and its functional implications

    PNAS 2005 102:5975-5980; published ahead of print April 19, 2005, doi:10.1073/pnas.0500149102
  • Biological Sciences - Biochemistry:
    • Mindy I. Davis,
    • Melanie J. Bennett,
    • Leonard M. Thomas,
    • and Pamela J. Bjorkman

    Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase

    PNAS 2005 102:5981-5986; published ahead of print April 18, 2005, doi:10.1073/pnas.0502101102
  • Biological Sciences - Biochemistry:
    • Anne-Laure Bulteau,
    • Kathleen C. Lundberg,
    • Masao Ikeda-Saito,
    • Grazia Isaya,
    • and Luke I. Szweda

    Reversible redox-dependent modulation of mitochondrial aconitase and proteolytic activity during in vivo cardiac ischemia/reperfusion

    PNAS 2005 102:5987-5991; published ahead of print April 19, 2005, doi:10.1073/pnas.0501519102
  • Biological Sciences - Biochemistry:
    • Arvind Ramanathan,
    • Connie Wang,
    • and Stuart L. Schreiber

    Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements

    PNAS 2005 102:5992-5997; published ahead of print April 19, 2005, doi:10.1073/pnas.0502267102
  • Biological Sciences - Biochemistry:
    • Sangkil Nam,
    • Ralf Buettner,
    • James Turkson,
    • Donghwa Kim,
    • Jin Q. Cheng,
    • Stephan Muehlbeyer,
    • Frankie Hippe,
    • Sandra Vatter,
    • Karl-Heinz Merz,
    • Gerhard Eisenbrand,
    • and Richard Jove

    Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells

    PNAS 2005 102:5998-6003; published ahead of print April 18, 2005, doi:10.1073/pnas.0409467102

Biophysics

  • Biological Sciences - Biophysics:
    • M. G. Sacerdote
    • and J. W. Szostak

    Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose

    PNAS 2005 102:6004-6008; published ahead of print April 14, 2005, doi:10.1073/pnas.0408440102
  • Biological Sciences - Biophysics:
    • Anna Codina,
    • James D. Love,
    • Yun Li,
    • Mitchell A. Lazar,
    • David Neuhaus,
    • and John W. R. Schwabe

    From the Cover: Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors

    PNAS 2005 102:6009-6014; published ahead of print April 18, 2005, doi:10.1073/pnas.0500299102
  • Biological Sciences - Biophysics:
    • Jose M. Borreguero,
    • Brigita Urbanc,
    • Noel D. Lazo,
    • Sergey V. Buldyrev,
    • David B. Teplow,
    • and H. Eugene Stanley

    Folding events in the 21-30 region of amyloid β-protein (Aβ) studied in silico

    PNAS 2005 102:6015-6020; published ahead of print April 18, 2005, doi:10.1073/pnas.0502006102

Cell Biology

  • Biological Sciences - Cell Biology:
    • Sandra Grau,
    • Alfonso Baldi,
    • Rossana Bussani,
    • Xiaodan Tian,
    • Raluca Stefanescu,
    • Michael Przybylski,
    • Peter Richards,
    • Simon A. Jones,
    • Viji Shridhar,
    • Tim Clausen,
    • and Michael Ehrmann

    Implications of the serine protease HtrA1 in amyloid precursor protein processing

    PNAS 2005 102:6021-6026; doi:10.1073/pnas.0501823102
  • Biological Sciences - Cell Biology:
    • Ming Yang,
    • Wendy W. Zhong,
    • Neelam Srivastava,
    • Anthony Slavin,
    • Jianxin Yang,
    • Timothy Hoey,
    • and Songzhu An

    G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the β-catenin pathway

    PNAS 2005 102:6027-6032; published ahead of print April 18, 2005, doi:10.1073/pnas.0501535102

Ecology

  • Biological Sciences - Ecology:
    • B. R. Scanlon,
    • D. G. Levitt,
    • R. C. Reedy,
    • K. E. Keese,
    • and M. J. Sully

    Ecological controls on water-cycle response to climate variability in deserts

    PNAS 2005 102:6033-6038; published ahead of print April 18, 2005, doi:10.1073/pnas.0408571102

Evolution

  • Biological Sciences - Evolution:
    • Yoshihito Niimura
    • and Masatoshi Nei

    From the Cover: Evolutionary dynamics of olfactory receptor genes in fishes and tetrapods

    PNAS 2005 102:6039-6044; published ahead of print April 11, 2005, doi:10.1073/pnas.0501922102
  • Biological Sciences - Evolution:
    • Donna Petfield,
    • Stephen F. Chenoweth,
    • Howard D. Rundle,
    • and Mark W. Blows

    Genetic variance in female condition predicts indirect genetic variance in male sexual display traits

    PNAS 2005 102:6045-6050; published ahead of print April 19, 2005, doi:10.1073/pnas.0409378102

Genetics

  • Biological Sciences - Genetics:
    • María J. García-García,
    • Jonathan T. Eggenschwiler,
    • Tamara Caspary,
    • Heather L. Alcorn,
    • Michael R. Wyler,
    • Danwei Huangfu,
    • Andrew S. Rakeman,
    • Jeffrey D. Lee,
    • Evan H. Feinberg,
    • John R. Timmer,
    • and Kathryn V. Anderson

    Inaugural Article: Analysis of mouse embryonic patterning and morphogenesis by forward genetics

    PNAS 2005 102:5913-5919; published ahead of print March 8, 2005, doi:10.1073/pnas.0501071102
    • See commentary article on page 5910 in issue 17 of volume 102
  • Biological Sciences - Genetics:
    • Anne Goriely,
    • Gilean A. T. McVean,
    • Ans M. M. van Pelt,
    • Anthony W. O'Rourke,
    • Steven A. Wall,
    • Dirk G. de Rooij,
    • and Andrew O. M. Wilkie

    Gain-of-function amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia

    PNAS 2005 102:6051-6056; published ahead of print April 19, 2005, doi:10.1073/pnas.0500267102
  • Biological Sciences - Genetics:
    • Akitsugu Sato,
    • Kazuto Nakada,
    • Miho Akimoto,
    • Kaori Ishikawa,
    • Tomoko Ono,
    • Hiroshi Shitara,
    • Hiromichi Yonekawa,
    • and Jun-Ichi Hayashi

    Rare creation of recombinant mtDNA haplotypes in mammalian tissues

    PNAS 2005 102:6057-6062; published ahead of print April 13, 2005, doi:10.1073/pnas.0408666102
  • Biological Sciences - Genetics:
    • Atsuko Shimada,
    • Akihiro Shima,
    • Kumie Nojima,
    • Yo Seino,
    • and Richard B. Setlow

    Germ cell mutagenesis in medaka fish after exposures to high-energy cosmic ray nuclei: A human model

    PNAS 2005 102:6063-6067; published ahead of print April 13, 2005, doi:10.1073/pnas.0500895102

Immunology

  • Biological Sciences - Immunology:
    • David M. Langenau,
    • Hui Feng,
    • Stephane Berghmans,
    • John P. Kanki,
    • Jeffery L. Kutok,
    • and A. Thomas Look

    Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia

    PNAS 2005 102:6068-6073; published ahead of print April 12, 2005, doi:10.1073/pnas.0408708102
  • Biological Sciences - Immunology:
    • Dana R. Marshall,
    • Elvia Olivas,
    • Samita Andreansky,
    • Nicole L. La Gruta,
    • Geoff A. Neale,
    • Astrid Gutierrez,
    • David G. Wichlan,
    • Suzette Wingo,
    • Cheng Cheng,
    • Peter C. Doherty,
    • and Stephen J. Turner

    Effector CD8 + T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression

    PNAS 2005 102:6074-6079; published ahead of print April 14, 2005, doi:10.1073/pnas.0501960102

Medical Sciences

  • Biological Sciences - Medical Sciences:
    • Lingfei Xu,
    • Timothy C. Nichols,
    • Rita Sarkar,
    • Stephanie McCorquodale,
    • Dwight A. Bellinger,
    • and Katherine P. Ponder

    Absence of a desmopressin response after therapeutic expression of factor VIII in hemophilia A dogs with liver-directed neonatal gene therapy

    PNAS 2005 102:6080-6085; published ahead of print April 18, 2005, doi:10.1073/pnas.0409249102
  • Biological Sciences - Medical Sciences:
    • Aimin Xu,
    • Michael C. Lam,
    • Kok Weng Chan,
    • Yu Wang,
    • Jialiang Zhang,
    • Ruby L. C. Hoo,
    • Jian Yu Xu,
    • Baoying Chen,
    • Wing-Sun Chow,
    • Annette W. K. Tso,
    • and Karen S. L. Lam

    Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice

    PNAS 2005 102:6086-6091; published ahead of print April 18, 2005, doi:10.1073/pnas.0408452102
  • Biological Sciences - Medical Sciences:
    • Christopher Haqq,
    • Mehdi Nosrati,
    • Daniel Sudilovsky,
    • Julia Crothers,
    • Daniel Khodabakhsh,
    • Brian L. Pulliam,
    • Scot Federman,
    • James R. Miller, III,
    • Robert E. Allen,
    • Mark I. Singer,
    • Stanley P. L. Leong,
    • Britt-Marie Ljung,
    • Richard W. Sagebiel,
    • and Mohammed Kashani-Sabet

    From the Cover: The gene expression signatures of melanoma progression

    PNAS 2005 102:6092-6097; published ahead of print April 15, 2005, doi:10.1073/pnas.0501564102
  • Biological Sciences - Medical Sciences:
    • Katarzyna Lundmark,
    • Gunilla T. Westermark,
    • Arne Olsén,
    • and Per Westermark

    Protein fibrils in nature can enhance amyloid protein A amyloidosis in mice: Cross-seeding as a disease mechanism

    PNAS 2005 102:6098-6102; published ahead of print April 13, 2005, doi:10.1073/pnas.0501814102

Microbiology

  • Biological Sciences - Microbiology:
    • Alexander G. Holman
    • and John M. Coffin

    Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites

    PNAS 2005 102:6103-6107; published ahead of print March 31, 2005, doi:10.1073/pnas.0501646102
    • See commentary article on page 5903 in issue 17 of volume 102
  • Biological Sciences - Microbiology:
    • F. Douglas Ivey
    • and Charles S. Hoffman

    Direct activation of fission yeast adenylate cyclase by the Gpa2 Gα of the glucose signaling pathway

    PNAS 2005 102:6108-6113; published ahead of print April 14, 2005, doi:10.1073/pnas.0502270102
  • Biological Sciences - Microbiology:
    • Donald A. Drew,
    • Mary J. Osborn,
    • and Lawrence I. Rothfield

    A polymerization-depolymerization model that accurately generates the self-sustained oscillatory system involved in bacterial division site placement

    PNAS 2005 102:6114-6118; published ahead of print April 19, 2005, doi:10.1073/pnas.0502037102
  • Biological Sciences - Microbiology: