Commentaries

  • Commentary:
    • Alan G. Sanfey
    • and Jonathan D. Cohen

    Is knowing always feeling?

    PNAS 2004 101:16709-16710; published ahead of print November 22, 2004, doi:10.1073/pnas.0407200101
    • See companion article on page 16075 in issue 45 of volume 101
  • Commentary:
    • Steven L. Teitelbaum

    Postmenopausal osteoporosis, T cells, and immune dysfunction

    PNAS 2004 101:16711-16712; published ahead of print November 22, 2004, doi:10.1073/pnas.0407335101
    • See companion article on page 16618 in issue 47 of volume 101
  • Commentary:
    • Laurie J. Vitt

    Shifting paradigms: Herbivory and body size in lizards

    PNAS 2004 101:16713-16714; published ahead of print November 22, 2004, doi:10.1073/pnas.0407439101
    • See companion article on page 16819 in issue 48 of volume 101

Physical Sciences

Applied Mathematics

  • Physical Sciences - Applied Mathematics - Biological Sciences - Neuroscience:
    • Lawrence Sirovich
    • and Robert Uglesich

    The organization of orientation and spatial frequency in primary visual cortex

    PNAS 2004 101:16941-16946; published ahead of print November 18, 2004, doi:10.1073/pnas.0407450101

Chemistry

  • Physical Sciences - Chemistry:
    • Christopher L. de Graffenried,
    • Scott T. Laughlin,
    • Jennifer J. Kohler,
    • and Carolyn R. Bertozzi

    From the Cover: A small-molecule switch for Golgi sulfotransferases

    PNAS 2004 101:16715-16720; published ahead of print November 17, 2004, doi:10.1073/pnas.0403681101
  • Physical Sciences - Chemistry:
    • Marcus A. Koch,
    • Lars-Oliver Wittenberg,
    • Sudipta Basu,
    • Duraiswamy A. Jeyaraj,
    • Eleni Gourzoulidou,
    • Kerstin Reinecke,
    • Alex Odermatt,
    • and Herbert Waldmann

    Compound library development guided by protein structure similarity clustering and natural product structure

    PNAS 2004 101:16721-16726; published ahead of print November 17, 2004, doi:10.1073/pnas.0404719101
  • Physical Sciences - Chemistry:
    • Susana Conde Ceide,
    • Laurent Trembleau,
    • Gebhard Haberhauer,
    • Laszlo Somogyi,
    • Xiaoying Lu,
    • Tamas Bartfai,
    • and Julius Rebek, Jr.

    Synthesis of galmic: A nonpeptide galanin receptor agonist

    PNAS 2004 101:16727-16732; published ahead of print November 19, 2004, doi:10.1073/pnas.0407543101
  • Physical Sciences - Chemistry:
    • Raphaël Plasson,
    • Hugues Bersini,
    • and Auguste Commeyras

    Recycling Frank: Spontaneous emergence of homochirality in noncatalytic systems

    PNAS 2004 101:16733-16738; published ahead of print November 17, 2004, doi:10.1073/pnas.0405293101

Statistics

  • Physical Sciences - Statistics:
    • Rui Feng,
    • James F. Leckman,
    • and Heping Zhang

    Linkage analysis of ordinal traits for pedigree data

    PNAS 2004 101:16739-16744; published ahead of print November 17, 2004, doi:10.1073/pnas.0404623101

Biological Sciences

Applied Biological Sciences

  • Biological Sciences - Applied Biological Sciences:
    • Lei Wang,
    • W. Coyt Jackson,
    • Paul A. Steinbach,
    • and Roger Y. Tsien

    Evolution of new nonantibody proteins via iterative somatic hypermutation

    PNAS 2004 101:16745-16749; published ahead of print November 19, 2004, doi:10.1073/pnas.0407752101

Biochemistry

  • Biological Sciences - Biochemistry:
    • Steven L. Kazmirski,
    • Marjetka Podobnik,
    • Tanya F. Weitze,
    • Mike O'Donnell,
    • and John Kuriyan

    Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex

    PNAS 2004 101:16750-16755; published ahead of print November 19, 2004, doi:10.1073/pnas.0407904101
  • Biological Sciences - Biochemistry:
    • Sen Zhang,
    • Alan Finkelstein,
    • and R. John Collier

    Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel

    PNAS 2004 101:16756-16761; published ahead of print November 17, 2004, doi:10.1073/pnas.0405754101
  • Biological Sciences - Biochemistry:
    • Wensheng Wang,
    • Patrick Brandt,
    • Marie L. Rossi,
    • Laura Lindsey-Boltz,
    • Vladimir Podust,
    • Ellen Fanning,
    • Aziz Sancar,
    • and Robert A. Bambara

    The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1

    PNAS 2004 101:16762-16767; published ahead of print November 19, 2004, doi:10.1073/pnas.0407686101
  • Biological Sciences - Biochemistry:
    • Bogdan Z. Olenyuk,
    • Guo-Jun Zhang,
    • Jeffery M. Klco,
    • Nicholas G. Nickols,
    • William G. Kaelin, Jr.,
    • and Peter B. Dervan

    Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist

    PNAS 2004 101:16768-16773; published ahead of print November 19, 2004, doi:10.1073/pnas.0407617101
  • Biological Sciences - Biochemistry:
    • Fernando Antunes,
    • Alberto Boveris,
    • and Enrique Cadenas

    On the mechanism and biology of cytochrome oxidase inhibition by nitric oxide

    PNAS 2004 101:16774-16779; published ahead of print November 16, 2004, doi:10.1073/pnas.0405368101

Biophysics

  • Biological Sciences - Biophysics:
    • A. S. Fokas,
    • I. M. Gelfand,
    • and A. E. Kister

    Prediction of the structural motifs of sandwich proteins

    PNAS 2004 101:16780-16783; published ahead of print November 18, 2004, doi:10.1073/pnas.0407570101
  • Biological Sciences - Biophysics:
    • S. Tonia Hsieh
    • and George V. Lauder

    Running on water: Three-dimensional force generation by basilisk lizards

    PNAS 2004 101:16784-16788; published ahead of print November 18, 2004, doi:10.1073/pnas.0405736101
  • Biological Sciences - Biophysics:
    • Pascal Auffinger,
    • Franklin A. Hays,
    • Eric Westhof,
    • and P. Shing Ho

    Halogen bonds in biological molecules

    PNAS 2004 101:16789-16794; published ahead of print November 19, 2004, doi:10.1073/pnas.0407607101

Cell Biology

  • Biological Sciences - Cell Biology:
    • Chau Huynh,
    • Doris Roth,
    • Diane M. Ward,
    • Jerry Kaplan,
    • and Norma W. Andrews

    From the Cover: Defective lysosomal exocytosis and plasma membrane repair in Chediak–Higashi/beige cells

    PNAS 2004 101:16795-16800; published ahead of print November 22, 2004, doi:10.1073/pnas.0405905101
  • Biological Sciences - Cell Biology:
    • Manrico Morroni,
    • Antonio Giordano,
    • Maria Cristina Zingaretti,
    • Romina Boiani,
    • Rita De Matteis,
    • Barbara B. Kahn,
    • Enzo Nisoli,
    • Cristina Tonello,
    • Catalina Pisoschi,
    • Michele M. Luchetti,
    • Mariella Marelli,
    • and Saverio Cinti

    Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland

    PNAS 2004 101:16801-16806; published ahead of print November 19, 2004, doi:10.1073/pnas.0407647101
  • Biological Sciences - Cell Biology:
    • Anthony O. Gramolini,
    • Thomas Kislinger,
    • Michio Asahi,
    • Wenping Li,
    • Andrew Emili,
    • and David H. MacLennan

    Sarcolipin retention in the endoplasmic reticulum depends on its C-terminal RSYQY sequence and its interaction with sarco(endo)plasmic Ca 2 +-ATPases

    PNAS 2004 101:16807-16812; published ahead of print November 19, 2004, doi:10.1073/pnas.0407815101
  • Biological Sciences - Cell Biology:
    • Jennifer LeCouter,
    • Constance Zlot,
    • Max Tejada,
    • Franklin Peale,
    • and Napoleone Ferrara

    Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization

    PNAS 2004 101:16813-16818; published ahead of print November 17, 2004, doi:10.1073/pnas.0407697101

Evolution

  • Biological Sciences - Evolution:
    • Robert E. Espinoza,
    • John J. Wiens,
    • and C. Richard Tracy

    From the Cover: Recurrent evolution of herbivory in small, cold-climate lizards: Breaking the ecophysiological rules of reptilian herbivory

    PNAS 2004 101:16819-16824; published ahead of print November 18, 2004, doi:10.1073/pnas.0401226101
    • See commentary article on page 16713 in issue 48 of volume 101
  • Biological Sciences - Evolution:
    • Roy J. Britten

    Coding sequences of functioning human genes derived entirely from mobile element sequences

    PNAS 2004 101:16825-16830; published ahead of print November 16, 2004, doi:10.1073/pnas.0406985101

Genetics

  • Biological Sciences - Genetics:
    • T. Norene O'Sullivan,
    • Xufeng S. Wu,
    • Rivka A. Rachel,
    • Jiang-Dong Huang,
    • Deborah A. Swing,
    • Lydia E. Matesic,
    • John A. Hammer, III,
    • Neal G. Copeland,
    • and Nancy A. Jenkins

    dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice

    PNAS 2004 101:16831-16836; published ahead of print November 18, 2004, doi:10.1073/pnas.0407339101
  • Biological Sciences - Genetics:
    • Peter J. Sabo,
    • Michael Hawrylycz,
    • James C. Wallace,
    • Richard Humbert,
    • Man Yu,
    • Anthony Shafer,
    • Janelle Kawamoto,
    • Robert Hall,
    • Joshua Mack,
    • Michael O. Dorschner,
    • Michael McArthur,
    • and John A. Stamatoyannopoulos

    Discovery of functional noncoding elements by digital analysis of chromatin structure

    PNAS 2004 101:16837-16842; published ahead of print November 18, 2004, doi:10.1073/pnas.0407387101
  • Biological Sciences - Genetics:
    • Sara J. Zanton
    • and B. Franklin Pugh

    Changes in genomewide occupancy of core transcriptional regulators during heat stress

    PNAS 2004 101:16843-16848; published ahead of print November 17, 2004, doi:10.1073/pnas.0404988101
  • Biological Sciences - Genetics:
    • Rim Rzem,
    • Maria Veiga-da-Cunha,
    • Gaëtane Noël,
    • Sophie Goffette,
    • Marie-Cécile Nassogne,
    • Brahim Tabarki,
    • Christina Schöller,
    • Thorsten Marquardt,
    • Miikka Vikkula,
    • and Emile Van Schaftingen

    A gene encoding a putative FAD-dependent l -2-hydroxyglutarate dehydrogenase is mutated in l -2-hydroxyglutaric aciduria

    PNAS 2004 101:16849-16854; published ahead of print November 17, 2004, doi:10.1073/pnas.0404840101
  • Biological Sciences - Genetics:
    • Lingang Zhang,
    • Simon Kasif,
    • Charles R. Cantor,
    • and Natalia E. Broude

    GC/AT-content spikes as genomic punctuation marks

    PNAS 2004 101:16855-16860; published ahead of print November 17, 2004, doi:10.1073/pnas.0407821101
  • Biological Sciences - Genetics:
    • Ichiro Hiratani,
    • Amanda Leskovar,
    • and David M. Gilbert

    Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochores

    PNAS 2004 101:16861-16866; published ahead of print November 19, 2004, doi:10.1073/pnas.0406687101

Immunology

  • Biological Sciences - Immunology:
    • Zhen-Yu J. Sun,
    • Sun Taek Kim,
    • Il Chul Kim,
    • Amr Fahmy,
    • Ellis L. Reinherz,
    • and Gerhard Wagner

    Solution structure of the CD3εδ ectodomain and comparison with CD3εγ as a basis for modeling T cell receptor topology and signaling

    PNAS 2004 101:16867-16872; published ahead of print November 19, 2004, doi:10.1073/pnas.0407576101
  • Biological Sciences - Immunology:
    • Bruno Vanherberghen,
    • Katja Andersson,
    • Leo M. Carlin,
    • Esther N. M. Nolte-`t Hoen,
    • Geoffrey S. Williams,
    • Petter Höglund,
    • and Daniel M. Davis

    Human and murine inhibitory natural killer cell receptors transfer from natural killer cells to target cells

    PNAS 2004 101:16873-16878; published ahead of print November 18, 2004, doi:10.1073/pnas.0406240101
  • Biological Sciences - Immunology:
    • Emma Andersson Nordahl,
    • Victoria Rydengård,
    • Patrik Nyberg,
    • D. Patric Nitsche,
    • Matthias Mörgelin,
    • Martin Malmsten,
    • Lars Björck,
    • and Artur Schmidtchen

    Activation of the complement system generates antibacterial peptides

    PNAS 2004 101:16879-16884; published ahead of print November 18, 2004, doi:10.1073/pnas.0406678101
  • Biological Sciences - Immunology:
    • Ananda W. Goldrath,
    • C. John Luckey,
    • Richard Park,
    • Christophe Benoist,
    • and Diane Mathis

    The molecular program induced in T cells undergoing homeostatic proliferation

    PNAS 2004 101:16885-16890; published ahead of print November 17, 2004, doi:10.1073/pnas.0407417101

Medical Sciences

  • Biological Sciences - Medical Sciences:
    • Shuguang Jiang,
    • Luke Walker,
    • Michael Afentoulis,
    • Daniel A. Anderson,
    • Linda Jauron-Mills,
    • Christopher L. Corless,
    • and William H. Fleming

    Transplanted human bone marrow contributes to vascular endothelium

    PNAS 2004 101:16891-16896; published ahead of print November 17, 2004, doi:10.1073/pnas.0404398101
  • Biological Sciences - Medical Sciences:
    • Manu Kohli,
    • Jian Yu,
    • Craig Seaman,
    • Alberto Bardelli,
    • Kenneth W. Kinzler,
    • Bert Vogelstein,
    • Christoph Lengauer,
    • and Lin Zhang

    SMAC/Diablo -dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells

    PNAS 2004 101:16897-16902; published ahead of print November 19, 2004, doi:10.1073/pnas.0403405101
  • Biological Sciences - Medical Sciences:
    • Heidi Erlandsen,
    • Angel L. Pey,
    • Alejandra Gámez,
    • Belén Pérez,
    • Lourdes R. Desviat,
    • Cristina Aguado,
    • Richard Koch,
    • Sankar Surendran,
    • Stephen Tyring,
    • Reuben Matalon,
    • Charles R. Scriver,
    • Magdalena Ugarte,
    • Aurora Martínez,
    • and Raymond C. Stevens

    From the Cover: Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations

    PNAS 2004 101:16903-16908; published ahead of print November 19, 2004, doi:10.1073/pnas.0407256101
  • Biological Sciences - Medical Sciences:
    • Makoto Yoshimitsu,
    • Takeya Sato,
    • Kesheng Tao,
    • Jagdeep S. Walia,
    • Vanessa I. Rasaiah,
    • Gillian T. Sleep,
    • Gary J. Murray,
    • Armando G. Poeppl,
    • John Underwood,
    • Lori West,
    • Roscoe O. Brady,
    • and Jeffrey A. Medin

    Bioluminescent imaging of a marking transgene and correction of Fabry mice by neonatal injection of recombinant lentiviral vectors

    PNAS 2004 101:16909-16914; published ahead of print November 18, 2004, doi:10.1073/pnas.0407572101
  • Biological Sciences - Medical Sciences:
    • Jonathan Dushoff,
    • Joshua B. Plotkin,
    • Simon A. Levin,
    • and David J. D. Earn

    Dynamical resonance can account for seasonality of influenza epidemics

    PNAS 2004 101:16915-16916; published ahead of print November 19, 2004, doi:10.1073/pnas.0407293101

Microbiology

  • Biological Sciences - Microbiology:
    • Paul G. Egland,
    • Robert J. Palmer, Jr.,
    • and Paul E. Kolenbrander

    Interspecies communication in Streptococcus gordonii–Veillonella atypica biofilms: Signaling in flow conditions requires juxtaposition

    PNAS 2004 101:16917-16922; published ahead of print November 16, 2004, doi:10.1073/pnas.0407457101
  • Biological Sciences - Microbiology:
    • Anna Bäckström,
    • Carina Lundberg,
    • Dangeruta Kersulyte,
    • Douglas E. Berg,
    • Thomas Borén,
    • and Anna Arnqvist

    From the Cover: Metastability of Helicobacter pylori bab adhesin genes and dynamics in Lewis b antigen binding