Commentaries

  • Commentary:
    • Stephen M. Rich

    The unpredictable past of Plasmodium vivax revealed in its genome

    PNAS 2004 101:15547-15548; published ahead of print October 25, 2004, doi:10.1073/pnas.0405618101
    • See companion article on page 14455 in issue 40 of volume 101
  • Commentary:
    • Adam Zlotnick

    Viruses and the physics of soft condensed matter

    PNAS 2004 101:15549-15550; published ahead of print October 25, 2004, doi:10.1073/pnas.0406935101
    • See companion article on page 15556 in issue 44 of volume 101

Physical Sciences

Applied Mathematics

  • Physical Sciences - Applied Mathematics:
    • Luís A. N. Amaral,
    • Albert Díaz-Guilera,
    • Andre A. Moreira,
    • Ary L. Goldberger,
    • and Lewis A. Lipsitz

    From the Cover: Emergence of complex dynamics in a simple model of signaling networks

    PNAS 2004 101:15551-15555; published ahead of print October 25, 2004, doi:10.1073/pnas.0404843101

Physics

  • Physical Sciences - Physics:
    • Roya Zandi,
    • David Reguera,
    • Robijn F. Bruinsma,
    • William M. Gelbart,
    • and Joseph Rudnick

    From the Cover: Origin of icosahedral symmetry in viruses

    PNAS 2004 101:15556-15560; published ahead of print October 14, 2004, doi:10.1073/pnas.0405844101
    • See commentary article on page 15549 in issue 44 of volume 101

Statistics

  • Physical Sciences - Statistics - Biological Sciences - Genetics:
    • Ker-Chau Li,
    • Ching-Ti Liu,
    • Wei Sun,
    • Shinsheng Yuan,
    • and Tianwei Yu

    A system for enhancing genome-wide coexpression dynamics study

    PNAS 2004 101:15561-15566; published ahead of print October 18, 2004, doi:10.1073/pnas.0402962101

Biological Sciences

Biochemistry

  • Biological Sciences - Biochemistry:
    • Bornali Chakravarty,
    • Ziwei Gu,
    • Subrahmanyam S. Chirala,
    • Salih J. Wakil,
    • and Florante A. Quiocho

    Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain

    PNAS 2004 101:15567-15572; published ahead of print October 26, 2004, doi:10.1073/pnas.0406901101
  • Biological Sciences - Biochemistry:
    • Sarah J. Kodumal,
    • Kedar G. Patel,
    • Ralph Reid,
    • Hugo G. Menzella,
    • Mark Welch,
    • and Daniel V. Santi

    Total synthesis of long DNA sequences: Synthesis of a contiguous 32-kb polyketide synthase gene cluster

    PNAS 2004 101:15573-15578; published ahead of print October 20, 2004, doi:10.1073/pnas.0406911101
  • Biological Sciences - Biochemistry:
    • Gianguido Coffa
    • and Alan R. Brash

    A single active site residue directs oxygenation stereospecificity in lipoxygenases: Stereocontrol is linked to the position of oxygenation

    PNAS 2004 101:15579-15584; published ahead of print October 20, 2004, doi:10.1073/pnas.0406727101
  • Biological Sciences - Biochemistry:
    • Martin Hahn
    • and Torsten Stachelhaus

    Selective interaction between nonribosomal peptide synthetases is facilitated by short communication-mediating domains

    PNAS 2004 101:15585-15590; published ahead of print October 21, 2004, doi:10.1073/pnas.0404932101
  • Biological Sciences - Biochemistry:
    • Alexander R. Horswill,
    • Sergey N. Savinov,
    • and Stephen J. Benkovic

    A systematic method for identifying small-molecule modulators of protein–protein interactions

    PNAS 2004 101:15591-15596; published ahead of print October 21, 2004, doi:10.1073/pnas.0406999101
  • Biological Sciences - Biochemistry:
    • Seiji Ishii,
    • Katsumi IIzuka,
    • Bonnie C. Miller,
    • and Kosaku Uyeda

    Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription

    PNAS 2004 101:15597-15602; published ahead of print October 20, 2004, doi:10.1073/pnas.0405238101
  • Biological Sciences - Biochemistry:
    • Jen-Chywan Wang,
    • Mika Kakefuda Derynck,
    • Daisuke F. Nonaka,
    • Daniel B. Khodabakhsh,
    • Chris Haqq,
    • and Keith R. Yamamoto

    From the Cover: Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes

    PNAS 2004 101:15603-15608; published ahead of print October 22, 2004, doi:10.1073/pnas.0407008101
  • Biological Sciences - Biochemistry:
    • Longkuan Xiang,
    • John A. Kalaitzis,
    • and Bradley S. Moore

    EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions

    PNAS 2004 101:15609-15614; published ahead of print October 25, 2004, doi:10.1073/pnas.0405508101
  • Biological Sciences - Biochemistry:
    • Hitoshi Sawada,
    • Etsuko Tanaka,
    • Susumu Ban,
    • Chiho Yamasaki,
    • Junko Fujino,
    • Kazuto Ooura,
    • Yukichi Abe,
    • Ken-ichi Matsumoto,
    • and Hideyoshi Yokosawa

    Self/nonself recognition in ascidian fertilization: Vitelline coat protein HrVC70 is a candidate allorecognition molecule

    PNAS 2004 101:15615-15620; published ahead of print October 25, 2004, doi:10.1073/pnas.0401928101

Biophysics

  • Biological Sciences - Biophysics:
    • D. Becker,
    • D. Geiger,
    • M. Dunkel,
    • A. Roller,
    • A. Bertl,
    • A. Latz,
    • A. Carpaneto,
    • P. Dietrich,
    • M. R. G. Roelfsema,
    • C. Voelker,
    • D. Schmidt,
    • B. Mueller-Roeber,
    • K. Czempinski,
    • and R. Hedrich

    AtTPK4, an Arabidopsis tandem-pore K + channel, poised to control the pollen membrane voltage in a pH- and Ca 2+ -dependent manner

    PNAS 2004 101:15621-15626; published ahead of print October 25, 2004, doi:10.1073/pnas.0401502101
  • Biological Sciences - Biophysics:
    • Brad J. Nolen,
    • Ryan S. Littlefield,
    • and Thomas D. Pollard

    Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP

    PNAS 2004 101:15627-15632; published ahead of print October 25, 2004, doi:10.1073/pnas.0407149101
  • Biological Sciences - Biophysics:
    • Paul G. Scott,
    • Paul A. McEwan,
    • Carole M. Dodd,
    • Ernst M. Bergmann,
    • Paul N. Bishop,
    • and Jordi Bella

    Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan

    PNAS 2004 101:15633-15638; published ahead of print October 22, 2004, doi:10.1073/pnas.0402976101
  • Biological Sciences - Biophysics:
    • W. Kevin Meisner
    • and Tobin R. Sosnick

    Barrier-limited, microsecond folding of a stable protein measured with hydrogen exchange: Implications for downhill folding

    PNAS 2004 101:15639-15644; published ahead of print October 25, 2004, doi:10.1073/pnas.0404895101
  • Biological Sciences - Biophysics:
    • Berta M. Martins,
    • Holger Dobbek,
    • Irfan Çinkaya,
    • Wolfgang Buckel,
    • and Albrecht Messerschmidt

    Crystal structure of 4-hydroxybutyryl-CoA dehydratase: Radical catalysis involving a [4Fe–4S] cluster and flavin

    PNAS 2004 101:15645-15649; published ahead of print October 20, 2004, doi:10.1073/pnas.0403952101

Cell Biology

  • Biological Sciences - Cell Biology:
    • Gonzalo E. Torres,
    • Ava L. Sweeney,
    • Jean-Martin Beaulieu,
    • Pullani Shashidharan,
    • and Marc G. Caron

    Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated ΔE-torsinA mutant

    PNAS 2004 101:15650-15655; published ahead of print October 25, 2004, doi:10.1073/pnas.0308088101

Developmental Biology

  • Biological Sciences - Developmental Biology:
    • Marcela Guzman-Ayala,
    • Nadav Ben-Haim,
    • Séverine Beck,
    • and Daniel B. Constam

    Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment

    PNAS 2004 101:15656-15660; published ahead of print October 25, 2004, doi:10.1073/pnas.0405429101

Ecology

  • Biological Sciences - Ecology:
    • Karl J. Niklas
    • and Hanns-Christof Spatz

    From the Cover: Growth and hydraulic (not mechanical) constraints govern the scaling of tree height and mass

    PNAS 2004 101:15661-15663; published ahead of print October 25, 2004, doi:10.1073/pnas.0405857101
  • Biological Sciences - Ecology:
    • Jon D. Witman,
    • Ron J. Etter,
    • and Franz Smith

    The relationship between regional and local species diversity in marine benthic communities: A global perspective

    PNAS 2004 101:15664-15669; published ahead of print October 22, 2004, doi:10.1073/pnas.0404300101

Evolution

  • Biological Sciences - Evolution:
    • Ana L. Caicedo,
    • John R. Stinchcombe,
    • Kenneth M. Olsen,
    • Johanna Schmitt,
    • and Michael D. Purugganan

    Epistatic interaction between Arabidopsis FRI and FLC flowering time genes generates a latitudinal cline in a life history trait

    PNAS 2004 101:15670-15675; published ahead of print October 25, 2004, doi:10.1073/pnas.0406232101

Genetics

  • Physical Sciences - Statistics - Biological Sciences - Genetics:
    • Ker-Chau Li,
    • Ching-Ti Liu,
    • Wei Sun,
    • Shinsheng Yuan,
    • and Tianwei Yu

    A system for enhancing genome-wide coexpression dynamics study

    PNAS 2004 101:15561-15566; published ahead of print October 18, 2004, doi:10.1073/pnas.0402962101
  • Biological Sciences - Genetics:
    • Chih-Hung Lai,
    • Helen H. Chun,
    • Shareef A. Nahas,
    • Midori Mitui,
    • Kristin M. Gamo,
    • Liutao Du,
    • and Richard A. Gatti

    Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons

    PNAS 2004 101:15676-15681; published ahead of print October 21, 2004, doi:10.1073/pnas.0405155101
  • Biological Sciences - Genetics:
    • Sharyl L. Wong,
    • Lan V. Zhang,
    • Amy H. Y. Tong,
    • Zhijian Li,
    • Debra S. Goldberg,
    • Oliver D. King,
    • Guillaume Lesage,
    • Marc Vidal,
    • Brenda Andrews,
    • Howard Bussey,
    • Charles Boone,
    • and Frederick P. Roth

    Combining biological networks to predict genetic interactions

    PNAS 2004 101:15682-15687; published ahead of print October 20, 2004, doi:10.1073/pnas.0406614101
  • Biological Sciences - Genetics:
    • Yonghong Li,
    • Petra Nowotny,
    • Peter Holmans,
    • Scott Smemo,
    • John S. K. Kauwe,
    • Anthony L. Hinrichs,
    • Kristina Tacey,
    • Lisa Doil,
    • Ryan van Luchene,
    • Veronica Garcia,
    • Charles Rowland,
    • Steve Schrodi,
    • Diane Leong,
    • Goran Gogic,
    • Joanne Chan,
    • Anibal Cravchik,
    • David Ross,
    • Kit Lau,
    • Shirley Kwok,
    • Sheng-Yung Chang,
    • Joe Catanese,
    • John Sninsky,
    • Thomas J. White,
    • John Hardy,
    • John Powell,
    • Simon Lovestone,
    • John C. Morris,
    • Leon Thal,
    • Michael Owen,
    • Julie Williams,
    • Alison Goate,
    • and Andrew Grupe

    Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family

    PNAS 2004 101:15688-15693; published ahead of print October 26, 2004, doi:10.1073/pnas.0403535101
  • Biological Sciences - Genetics:
    • Mitch McVey,
    • Jeannine R. LaRocque,
    • Melissa D. Adams,
    • and Jeff J. Sekelsky

    Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion

    PNAS 2004 101:15694-15699; published ahead of print October 22, 2004, doi:10.1073/pnas.0406157101
  • Biological Sciences - Genetics:
    • Gene Yeo,
    • Shawn Hoon,
    • Byrappa Venkatesh,
    • and Christopher B. Burge

    Variation in sequence and organization of splicing regulatory elements in vertebrate genes

    PNAS 2004 101:15700-15705; published ahead of print October 25, 2004, doi:10.1073/pnas.0404901101

Immunology

  • Biological Sciences - Immunology:
    • Jeffrey A. Yoder,
    • Ronda T. Litman,
    • M. Gail Mueller,
    • Salil Desai,
    • Kimberly P. Dobrinski,
    • Jennifer S. Montgomery,
    • Matthew P. Buzzeo,
    • Tatsuya Ota,
    • Chris T. Amemiya,
    • Nikolaus S. Trede,
    • Sheng Wei,
    • Julie Y. Djeu,
    • Sean Humphray,
    • Kerstin Jekosch,
    • Jose A. Hernandez Prada,
    • David A. Ostrov,
    • and Gary W. Litman

    Resolution of the novel immune-type receptor gene cluster in zebrafish

    PNAS 2004 101:15706-15711; published ahead of print October 20, 2004, doi:10.1073/pnas.0405242101
  • Biological Sciences - Immunology:
    • Stéphanie Eyquem,
    • Karine Chemin,
    • Magali Fasseu,
    • and Jean-Christophe Bories

    The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor β locus

    PNAS 2004 101:15712-15717; published ahead of print October 20, 2004, doi:10.1073/pnas.0405546101

Medical Sciences

  • Biological Sciences - Medical Sciences:
    • Fredrik Bäckhed,
    • Hao Ding,
    • Ting Wang,
    • Lora V. Hooper,
    • Gou Young Koh,
    • Andras Nagy,
    • Clay F. Semenkovich,
    • and Jeffrey I. Gordon

    The gut microbiota as an environmental factor that regulates fat storage

    PNAS 2004 101:15718-15723; published ahead of print October 25, 2004, doi:10.1073/pnas.0407076101
  • Biological Sciences - Medical Sciences:
    • Dafang Wan,
    • Yi Gong,
    • Wenxin Qin,
    • Pingping Zhang,
    • Jinjun Li,
    • Lin Wei,
    • Xiaomei Zhou,
    • Hongnian Li,
    • Xiaokun Qiu,
    • Fei Zhong,
    • Liping He,
    • Jian Yu,
    • Genfu Yao,
    • Huiqiu Jiang,
    • Lianfang Qian,
    • Ye Yu,
    • Huiqun Shu,
    • Xianlian Chen,
    • Huili Xu,
    • Minglei Guo,
    • Zhimei Pan,
    • Yan Chen,
    • Chao Ge,
    • Shengli Yang,
    • and Jianren Gu

    Large-scale cDNA transfection screening for genes related to cancer development and progression

    PNAS 2004 101:15724-15729; published ahead of print October 21, 2004, doi:10.1073/pnas.0404089101
  • Biological Sciences - Medical Sciences:
    • Suzanne Stewart,
    • Christopher W. Dawson,
    • Kenzo Takada,
    • John Curnow,
    • Cary A. Moody,
    • John W. Sixbey,
    • and Lawrence S. Young

    Epstein–Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-κB transcription factor pathway

    PNAS 2004 101:15730-15735; published ahead of print October 21, 2004, doi:10.1073/pnas.0402135101
  • Biological Sciences - Medical Sciences:
    • Stefano Fiorucci,
    • John L. Wallace,
    • Andrea Mencarelli,
    • Eleonora Distrutti,
    • Giovanni Rizzo,
    • Silvana Farneti,
    • Antonio Morelli,
    • Jih-Lie Tseng,
    • Babu Suramanyam,
    • William J. Guilford,
    • and John F. Parkinson

    A β-oxidation-resistant lipoxin A 4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction

    PNAS 2004 101:15736-15741; published ahead of print October 25, 2004, doi:10.1073/pnas.0404722101

Microbiology

  • Biological Sciences - Microbiology:
    • Rui Lu,
    • Alexey Folimonov,
    • Michael Shintaku,
    • Wan-Xiang Li,
    • Bryce W. Falk,
    • William O. Dawson,
    • and Shou-Wei Ding

    Three distinct suppressors of RNA silencing encoded by a 20-kb viral RNA genome

    PNAS 2004 101:15742-15747; published ahead of print October 25, 2004, doi:10.1073/pnas.0404940101
  • Biological Sciences - Microbiology:
    • Scott A. Jeffers,
    • Sonia M. Tusell,
    • Laura Gillim-Ross,
    • Erin M. Hemmila,
    • Jenna E. Achenbach,
    • Gregory J. Babcock,
    • William D. Thomas, Jr.,
    • Larissa B. Thackray,
    • Mark D. Young,
    • Robert J. Mason,
    • Donna M. Ambrosino,
    • David E. Wentworth,
    • James C. DeMartini,
    • and Kathryn V. Holmes

    CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus

    PNAS 2004 101:15748-