Table of Contents

Commentaries

Commentary:
- Dingzhi Wang
- and Raymond N. DuBois
Cyclooxygenase 2-derived prostaglandin E 2 regulates the angiogenic switch
PNAS 2004 101:415-416; published ahead of print January 5, 2004, doi:10.1073/pnas.0307640100
- See companion article on page 591 in issue 2 of volume 101
Commentary:
- Marilyn D. Resh
A myristoyl switch regulates membrane binding of HIV-1 Gag
PNAS 2004 101:417-418; published ahead of print January 5, 2004, doi:10.1073/pnas.0308043101
- See companion article on page 517 in issue 2 of volume 101

Physical Sciences

Chemistry

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Physical Sciences - Chemistry:
- J. Catalán,
- P. Pérez,
- J. C. del Valle,
- J. L. G. de Paz,
- and M. Kasha
H-bonded N-heterocyclic base-pair phototautomerizational potential barrier and mechanism: The 7-azaindole dimer
PNAS 2004 101:419-422; published ahead of print December 30, 2003, doi:10.1073/pnas.0306721101

Geophysics

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Physical Sciences - Geophysics:
- James Hansen
- and Larissa Nazarenko
Soot climate forcing via snow and ice albedos
PNAS 2004 101:423-428; published ahead of print December 29, 2003, doi:10.1073/pnas.2237157100

Physics

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Physical Sciences - Physics:
- Tae-Woo Lee,
- Jana Zaumseil,
- Zhenan Bao,
- Julia W. P. Hsu,
- and John A. Rogers
Organic light-emitting diodes formed by soft contact lamination
PNAS 2004 101:429-433; published ahead of print January 2, 2004, doi:10.1073/pnas.0304179101

Biological Sciences

Biophysics

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Biological Sciences - Biophysics:
- Andrew Moran
- and Shaul Mukamel
The origin of vibrational mode couplings in various secondary structural motifs of polypeptides
PNAS 2004 101:506-510; published ahead of print January 2, 2004, doi:10.1073/pnas.2533089100
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Biological Sciences - Biophysics:
- Yaakov Levy,
- Peter G. Wolynes,
- and José N. Onuchic
Protein topology determines binding mechanism
PNAS 2004 101:511-516; published ahead of print December 23, 2003, doi:10.1073/pnas.2534828100
Select this article
Biological Sciences - Biophysics:
- Chun Tang,
- Erin Loeliger,
- Paz Luncsford,
- Isaac Kinde,
- Dorothy Beckett,
- and Michael F. Summers
From the Cover: Entropic switch regulates myristate exposure in the HIV-1 matrix protein
PNAS 2004 101:517-522; published ahead of print December 29, 2003, doi:10.1073/pnas.0305665101
- See commentary article on page 417 in issue 2 of volume 101
Select this article
Biological Sciences - Biophysics:
- Zoya Ignatova
- and Lila M. Gierasch
Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling
PNAS 2004 101:523-528; published ahead of print December 30, 2003, doi:10.1073/pnas.0304533101
Select this article
Biological Sciences - Biophysics:
- Dmitry Bloch,
- Ilya Belevich,
- Audrius Jasaitis,
- Camilla Ribacka,
- Anne Puustinen,
- Michael I. Verkhovsky,
- and Mårten Wikström
The catalytic cycle of cytochrome c oxidase is not the sum of its two halves
PNAS 2004 101:529-533; published ahead of print December 29, 2003, doi:10.1073/pnas.0306036101
Select this article
Biological Sciences - Biophysics:
- Zheng Xie,
- Narayanan Srividya,
- Tobin R. Sosnick,
- Tao Pan,
- and Norbert F. Scherer
Single-molecule studies highlight conformational heterogeneity in the early folding steps of a large ribozyme
PNAS 2004 101:534-539; published ahead of print January 2, 2004, doi:10.1073/pnas.2636333100

Cell Biology

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Biological Sciences - Cell Biology:
- Constantine S. Mitsiades,
- Nicholas S. Mitsiades,
- Ciaran J. McMullan,
- Vassiliki Poulaki,
- Reshma Shringarpure,
- Teru Hideshima,
- Masaharu Akiyama,
- Dharminder Chauhan,
- Nikhil Munshi,
- Xuesong Gu,
- Charles Bailey,
- Marie Joseph,
- Towia A. Libermann,
- Victoria M. Richon,
- Paul A. Marks,
- and Kenneth C. Anderson
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications
PNAS 2004 101:540-545; published ahead of print December 26, 2003, doi:10.1073/pnas.2536759100
Select this article
Biological Sciences - Cell Biology:
- Sang Yoon Lee,
- Markus R. Wenk,
- Yong Kim,
- Angus C. Nairn,
- and Pietro De Camilli
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses
PNAS 2004 101:546-551; published ahead of print January 2, 2004, doi:10.1073/pnas.0307813100
- See commentary article on page 1112 in issue 5 of volume 101
Select this article
Biological Sciences - Cell Biology:
- Christopher L. Tinkle,
- Terry Lechler,
- H. Amalia Pasolli,
- and Elaine Fuchs
Conditional targeting of E-cadherin in skin: Insights into hyperproliferative and degenerative responses
PNAS 2004 101:552-557; published ahead of print January 2, 2004, doi:10.1073/pnas.0307437100

Ecology

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Biological Sciences - Ecology:
- James V. Briskie
- and Myles Mackintosh
From the Cover: Hatching failure increases with severity of population bottlenecks in birds
PNAS 2004 101:558-561; published ahead of print December 29, 2003, doi:10.1073/pnas.0305103101
Select this article
Biological Sciences - Ecology:
- David M. Nelson,
- Feng Sheng Hu,
- Jian Tian,
- Ivanka Stefanova,
- and Thomas A. Brown
Response of C 3 and C 4 plants to middle-Holocene climatic variation near the prairie–forest ecotone of Minnesota
PNAS 2004 101:562-567; published ahead of print December 30, 2003, doi:10.1073/pnas.0307450100

Evolution

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Biological Sciences - Evolution:
- Anne Rantala,
- David P. Fewer,
- Michael Hisbergues,
- Leo Rouhiainen,
- Jaana Vaitomaa,
- Thomas Börner,
- and Kaarina Sivonen
Phylogenetic evidence for the early evolution of microcystin synthesis
PNAS 2004 101:568-573; published ahead of print December 30, 2003, doi:10.1073/pnas.0304489101

Genetics

Select this article
Biological Sciences - Genetics:
- N. A. C. S. Wong,
- M. P. Britton,
- G. S. Choi,
- T. K. Stanton,
- D. C. Bicknell,
- J. L. Wilding,
- and W. F. Bodmer
Loss of CDX1 expression in colorectal carcinoma: Promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines
PNAS 2004 101:574-579; published ahead of print January 2, 2004, doi:10.1073/pnas.0307190101
Select this article
Biological Sciences - Genetics:
- Paul François
- and Vincent Hakim
Design of genetic networks with specified functions by evolution in silico
PNAS 2004 101:580-585; published ahead of print January 2, 2004, doi:10.1073/pnas.0304532101

Immunology

Select this article
Biological Sciences - Immunology:
- Margaret M. Mentink-Kane,
- Allen W. Cheever,
- Robert W. Thompson,
- Danielle M. Hari,
- Narcis B. Kabatereine,
- Birgitte J. Vennervald,
- John H. Ouma,
- Joseph K. Mwatha,
- Frances M. Jones,
- Debra D. Donaldson,
- Michael J. Grusby,
- David W. Dunne,
- and Thomas A. Wynn
IL-13 receptor α 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis
PNAS 2004 101:586-590; published ahead of print December 29, 2003, doi:10.1073/pnas.0305064101

Medical Sciences

Select this article
Biological Sciences - Medical Sciences:
- Sung-Hee Chang,
- Catherine H. Liu,
- Rebecca Conway,
- David K. Han,
- Kasem Nithipatikom,
- Ovidiu C. Trifan,
- Timothy F. Lane,
- and Timothy Hla
From the Cover: Role of prostaglandin E 2 -dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression
PNAS 2004 101:591-596; published ahead of print December 19, 2003, doi:10.1073/pnas.2535911100
- See commentary article on page 415 in issue 2 of volume 101
Select this article
Biological Sciences - Medical Sciences:
- Benjamin S. Braun,
- David A. Tuveson,
- Namie Kong,
- Doan T. Le,
- Scott C. Kogan,
- Jacob Rozmus,
- Michelle M. Le Beau,
- Tyler E. Jacks,
- and Kevin M. Shannon
Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder
PNAS 2004 101:597-602; published ahead of print December 29, 2003, doi:10.1073/pnas.0307203101
Select this article
Biological Sciences - Medical Sciences:
- A. J. T. Schuldt,
- T. J. Hampton,
- V. Chu,
- C. A. Vogler,
- N. Galvin,
- M. D. Lessard,
- and J. E. Barker
Electrocardiographic and other cardiac anomalies in β-glucuronidase-null mice corrected by nonablative neonatal marrow transplantation
PNAS 2004 101:603-608; published ahead of print January 2, 2004, doi:10.1073/pnas.0305284101
Select this article
Biological Sciences - Medical Sciences:
- Jay Y. Cho,
- Changsheng Guo,
- Monica Torello,
- Gregory P. Lunstrum,
- Tomoko Iwata,
- Chuxia Deng,
- and William A. Horton
Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia
PNAS 2004 101:609-614; published ahead of print December 29, 2003, doi:10.1073/pnas.2237184100
Select this article
Biological Sciences - Medical Sciences:
- Robert O. Stuart,
- William Wachsman,
- Charles C. Berry,
- Jessica Wang-Rodriguez,
- Linda Wasserman,
- Igor Klacansky,
- Dan Masys,
- Karen Arden,
- Steven Goodison,
- Michael McClelland,
- Yipeng Wang,
- Anne Sawyers,
- Iveta Kalcheva,
- David Tarin,
- and Dan Mercola
In silico dissection of cell-type-associated patterns of gene expression in prostate cancer
PNAS 2004 101:615-620; doi:10.1073/pnas.2536479100
Select this article
Biological Sciences - Medical Sciences:
- Xu Song,
- Aiwei Sui,
- and Alan Garen
Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: Effects on steroidogenesis and oncogenesis
PNAS 2004 101:621-626; published ahead of print January 2, 2004, doi:10.1073/pnas.0307794100

Microbiology

Select this article
Biological Sciences - Microbiology:
- Xibing Li
- and Saul Roseman
The chitinolytic cascade in Vibrios is regulated by chitin oligosaccharides and a two-component chitin catabolic sensor/kinase
PNAS 2004 101:627-631; published ahead of print December 29, 2003, doi:10.1073/pnas.0307645100
Select this article
Biological Sciences - Microbiology:
- Que Dang,
- Jianbo Chen,
- Derya Unutmaz,
- John M. Coffin,
- Vinay K. Pathak,
- Douglas Powell,
- Vineet N. KewalRamani,
- Frank Maldarelli,
- and Wei-Shau Hu
Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways
PNAS 2004 101:632-637; published ahead of print January 5, 2004, doi:10.1073/pnas.0307636100
Select this article
Biological Sciences - Microbiology:
- Jesse Summers
- and William S. Mason
Residual integrated viral DNA after hepadnavirus clearance by nucleoside analog therapy
PNAS 2004 101:638-640; published ahead of print December 29, 2003, doi:10.1073/pnas.0307422100

FROM THE COVER

Cyclooxygenase 2-derived prostaglandin E 2 regulates the angiogenic switch

A myristoyl switch regulates membrane binding of HIV-1 Gag

H-bonded N-heterocyclic base-pair phototautomerizational potential barrier and mechanism: The 7-azaindole dimer

Soot climate forcing via snow and ice albedos

Organic light-emitting diodes formed by soft contact lamination

Identification of Lhp1p-associated RNAs by microarray analysis in Saccharomyces cerevisiae reveals association with coding and noncoding RNAs

The second extracellular loop of the dopamine D 2 receptor lines the binding-site crevice

A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans

Bacillus subtilis RecU protein cleaves Holliday junctions and anneals single-stranded DNA

Myc-interacting protein 1 target gene profile: A link to microtubules, extracellular signal-regulated kinase, and cell growth

Physical and functional interaction of androgen receptor with calmodulin in prostate cancer cells

From the Cover: A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph

Context-dependent regulation of GATA-1 by friend of GATA-1

Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization

From the Cover: Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA

Availability of specific reductases controls the temporal activity of the cytochrome P450 complement of Streptomyces coelicolor A3(2)

Demonstration of mammalian protein O -mannosyltransferase activity: Coexpression of POMT1 and POMT2 required for enzymatic activity

The origin of vibrational mode couplings in various secondary structural motifs of polypeptides

Protein topology determines binding mechanism

From the Cover: Entropic switch regulates myristate exposure in the HIV-1 matrix protein

Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling

The catalytic cycle of cytochrome c oxidase is not the sum of its two halves

Single-molecule studies highlight conformational heterogeneity in the early folding steps of a large ribozyme

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications

Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses

Conditional targeting of E-cadherin in skin: Insights into hyperproliferative and degenerative responses

From the Cover: Hatching failure increases with severity of population bottlenecks in birds

Response of C 3 and C 4 plants to middle-Holocene climatic variation near the prairie–forest ecotone of Minnesota

Phylogenetic evidence for the early evolution of microcystin synthesis

Loss of CDX1 expression in colorectal carcinoma: Promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines

Design of genetic networks with specified functions by evolution in silico

IL-13 receptor α 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis

From the Cover: Role of prostaglandin E 2 -dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

Electrocardiographic and other cardiac anomalies in β-glucuronidase-null mice corrected by nonablative neonatal marrow transplantation

Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia

In silico dissection of cell-type-associated patterns of gene expression in prostate cancer

Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: Effects on steroidogenesis and oncogenesis

The chitinolytic cascade in Vibrios is regulated by chitin oligosaccharides and a two-component chitin catabolic sensor/kinase

Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways

Residual integrated viral DNA after hepadnavirus clearance by nucleoside analog therapy