Commentaries

  • Commentary:
    • Michel Tibayrenc

    A molecular biology approach to tuberculosis

    PNAS 2004 101:4721-4722; published ahead of print March 29, 2004, doi:10.1073/pnas.0400877101
    • See companion article on page 4871 in issue 14 of volume 101
    • See companion article on page 4865 in issue 14 of volume 101
  • Commentary:
    • Daniel Medina

    Stromal fibroblasts influence human mammary epithelial cell morphogenesis

    PNAS 2004 101:4723-4724; published ahead of print March 29, 2004, doi:10.1073/pnas.0401376101
    • See companion article on page 4966 in issue 14 of volume 101

Biography

  • Biography:
    • Christen Brownlee

    Inaugural Article: Biography of Enrico Coen

    PNAS 2004 101:4725-4727; published ahead of print March 29, 2004, doi:10.1073/pnas.0401746101
    • See commentary article on page 4728 in issue 14 of volume 101

Physical Sciences

Applied Mathematics

  • Physical Sciences - Applied Mathematics:
    • Andrew J. Majda
    • and Joseph A. Biello

    A multiscale model for tropical intraseasonal oscillations

    PNAS 2004 101:4736-4741; published ahead of print March 24, 2004, doi:10.1073/pnas.0401034101

Physics

  • Physical Sciences - Physics:
    • E. Holmström,
    • L. Nordström,
    • L. Bergqvist,
    • B. Skubic,
    • B. Hjörvarsson,
    • I. A. Abrikosov,
    • P. Svedlindh,
    • and O. Eriksson

    From the Cover: On the sharpness of the interfaces in metallic multilayers

    PNAS 2004 101:4742-4745; published ahead of print March 26, 2004, doi:10.1073/pnas.0305313101

Social Sciences

Economic Sciences

  • Social Sciences - Economic Sciences:
    • Prajit K. Dutta
    • and Roy Radner

    Self-enforcing climate-change treaties

    PNAS 2004 101:5174-5179; published ahead of print March 29, 2004, doi:10.1073/pnas.0400489101

Biological Sciences

Anthropology

  • Biological Sciences - Anthropology:
    • Thierry Wirth,
    • Xiaoyan Wang,
    • Bodo Linz,
    • Richard P. Novick,
    • J. Koji Lum,
    • Martin Blaser,
    • Giovanna Morelli,
    • Daniel Falush,
    • and Mark Achtman

    Distinguishing human ethnic groups by means of sequences from Helicobacter pylori : Lessons from Ladakh

    PNAS 2004 101:4746-4751; published ahead of print March 29, 2004, doi:10.1073/pnas.0306629101

Biochemistry

  • Biological Sciences - Biochemistry:
    • Qinghai Zhang,
    • Evan T. Powers,
    • Jorge Nieva,
    • Mary E. Huff,
    • Maria A. Dendle,
    • Jan Bieschke,
    • Charles G. Glabe,
    • Albert Eschenmoser,
    • Paul Wentworth, Jr.,
    • Richard A. Lerner,
    • and Jeffery W. Kelly

    Metabolite-initiated protein misfolding may trigger Alzheimer's disease

    PNAS 2004 101:4752-4757; published ahead of print March 19, 2004, doi:10.1073/pnas.0400924101
  • Biological Sciences - Biochemistry:
    • Paul L. Shaffer,
    • Arif Jivan,
    • D. Eric Dollins,
    • Frank Claessens,
    • and Daniel T. Gewirth

    Structural basis of androgen receptor binding to selective androgen response elements

    PNAS 2004 101:4758-4763; published ahead of print March 22, 2004, doi:10.1073/pnas.0401123101
  • Biological Sciences - Biochemistry:
    • Daniel Clayton,
    • George Shapovalov,
    • Joshua A. Maurer,
    • Dennis A. Dougherty,
    • Henry A. Lester,
    • and Gerd G. Kochendoerfer

    Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis

    PNAS 2004 101:4764-4769; published ahead of print March 23, 2004, doi:10.1073/pnas.0305693101
  • Biological Sciences - Biochemistry:
    • Tohru Yamada,
    • Yoshinori Hiraoka,
    • Masateru Ikehata,
    • Kazuhide Kimbara,
    • Benjamin S. Avner,
    • Tapas K. Das Gupta,
    • and Ananda M. Chakrabarty

    Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin

    PNAS 2004 101:4770-4775; published ahead of print March 24, 2004, doi:10.1073/pnas.0400899101

Biophysics

  • Biological Sciences - Biophysics:
    • Andrey Revyakin,
    • Richard H. Ebright,
    • and Terence R. Strick

    Promoter unwinding and promoter clearance by RNA polymerase: Detection by single-molecule DNA nanomanipulation

    PNAS 2004 101:4776-4780; published ahead of print March 22, 2004, doi:10.1073/pnas.0307241101
  • Biological Sciences - Biophysics - Cell Biology:
    • Fangting Li,
    • Tao Long,
    • Ying Lu,
    • Qi Ouyang,
    • and Chao Tang

    The yeast cell-cycle network is robustly designed

    PNAS 2004 101:4781-4786; published ahead of print March 22, 2004, doi:10.1073/pnas.0305937101
  • Biological Sciences - Biophysics:
    • Amel Bahloul,
    • Guillaume Chevreux,
    • Amber L. Wells,
    • Davy Martin,
    • Jocelyn Nolt,
    • Zhaohui Yang,
    • Li-Qiong Chen,
    • Noëlle Potier,
    • Alain Van Dorsselaer,
    • Steve Rosenfeld,
    • Anne Houdusse,
    • and H. Lee Sweeney

    The unique insert in myosin VI is a structural calcium–calmodulin binding site

    PNAS 2004 101:4787-4792; published ahead of print March 22, 2004, doi:10.1073/pnas.0306892101
  • Biological Sciences - Biophysics:
    • Bertil Halle

    Biomolecular cryocrystallography: Structural changes during flash-cooling

    PNAS 2004 101:4793-4798; published ahead of print March 29, 2004, doi:10.1073/pnas.0308315101
  • Biological Sciences - Biophysics:
    • Marius Schmidt,
    • Reinhard Pahl,
    • Vukica Srajer,
    • Spencer Anderson,
    • Zhong Ren,
    • Hyotcherl Ihee,
    • Sudarshan Rajagopal,
    • and Keith Moffat

    Protein kinetics: Structures of intermediates and reaction mechanism from time-resolved x-ray data

    PNAS 2004 101:4799-4804; published ahead of print March 23, 2004, doi:10.1073/pnas.0305983101
  • Biological Sciences - Biophysics:
    • Sapar M. Saparov
    • and Peter Pohl

    Beyond the diffusion limit: Water flow through the empty bacterial potassium channel

    PNAS 2004 101:4805-4809; published ahead of print March 19, 2004, doi:10.1073/pnas.0308309101

Cell Biology

  • Biological Sciences - Biophysics - Cell Biology:
    • Fangting Li,
    • Tao Long,
    • Ying Lu,
    • Qi Ouyang,
    • and Chao Tang

    The yeast cell-cycle network is robustly designed

    PNAS 2004 101:4781-4786; published ahead of print March 22, 2004, doi:10.1073/pnas.0305937101
  • Biological Sciences - Cell Biology:
    • Svetlana Deryusheva
    • and Joseph G. Gall

    Dynamics of coilin in Cajal bodies of the Xenopus germinal vesicle

    PNAS 2004 101:4810-4814; published ahead of print March 24, 2004, doi:10.1073/pnas.0401106101
  • Biological Sciences - Cell Biology:
    • Masayoshi Fukasawa,
    • Oleg Varlamov,
    • William S. Eng,
    • Thomas H. Söllner,
    • and James E. Rothman

    Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation

    PNAS 2004 101:4815-4820; published ahead of print March 24, 2004, doi:10.1073/pnas.0401183101
  • Biological Sciences - Cell Biology:
    • Akrit Sodhi,
    • Silvia Montaner,
    • Vyomesh Patel,
    • José Javier Gómez-Román,
    • Yi Li,
    • Edward A. Sausville,
    • Earl T. Sawai,
    • and J. Silvio Gutkind

    Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor

    PNAS 2004 101:4821-4826; published ahead of print March 26, 2004, doi:10.1073/pnas.0400835101
  • Biological Sciences - Cell Biology:
    • Damien Derouet,
    • François Rousseau,
    • Fabienne Alfonsi,
    • Josy Froger,
    • Jacques Hermann,
    • Fabien Barbier,
    • David Perret,
    • Caroline Diveu,
    • Catherine Guillet,
    • Laurence Preisser,
    • Agnès Dumont,
    • Maud Barbado,
    • Alain Morel,
    • Odile deLapeyrière,
    • Hugues Gascan,
    • and Sylvie Chevalier

    Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor

    PNAS 2004 101:4827-4832; published ahead of print March 29, 2004, doi:10.1073/pnas.0306178101
  • Biological Sciences - Cell Biology:
    • Shouwen Wang,
    • Xingbin Ai,
    • Stephen D. Freeman,
    • Mary E. Pownall,
    • Qun Lu,
    • Daniel S. Kessler,
    • and Charles P. Emerson, Jr.

    QSulf1, a heparan sulfate 6- O -endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis

    PNAS 2004 101:4833-4838; published ahead of print March 29, 2004, doi:10.1073/pnas.0401028101

Developmental Biology

  • Biological Sciences - Developmental Biology:
    • Enrico Coen,
    • Anne-Gaëlle Rolland-Lagan,
    • Mark Matthews,
    • J. Andrew Bangham,
    • and Przemyslaw Prusinkiewicz

    Inaugural Article: The genetics of geometry

    PNAS 2004 101:4728-4735; published ahead of print February 11, 2004, doi:10.1073/pnas.0306308101
    • See commentary article on page 4725 in issue 14 of volume 101
  • Biological Sciences - Developmental Biology:
    • Biswajit Das
    • and Donald D. Brown

    Controlling transgene expression to study Xenopus laevis metamorphosis

    PNAS 2004 101:4839-4842; published ahead of print March 26, 2004, doi:10.1073/pnas.0401011101
  • Biological Sciences - Developmental Biology:
    • Sophie Creuzet,
    • Bernadette Schuler,
    • Gérard Couly,
    • and Nicole M. Le Douarin

    From the Cover: Reciprocal relationships between Fgf8 and neural crest cells in facial and forebrain development

    PNAS 2004 101:4843-4847; published ahead of print March 23, 2004, doi:10.1073/pnas.0400869101
  • Biological Sciences - Developmental Biology:
    • Xu Huang,
    • Yuqing Dong,
    • and Jindong Zhao

    HetR homodimer is a DNA-binding protein required for heterocyst differentiation, and the DNA-binding activity is inhibited by PatS

    PNAS 2004 101:4848-4853; published ahead of print March 29, 2004, doi:10.1073/pnas.0400429101

Ecology

  • Biological Sciences - Ecology:
    • K. Ullas Karanth,
    • James D. Nichols,
    • N. Samba Kumar,
    • William A. Link,
    • and James E. Hines

    Tigers and their prey: Predicting carnivore densities from prey abundance

    PNAS 2004 101:4854-4858; published ahead of print March 23, 2004, doi:10.1073/pnas.0306210101
  • Biological Sciences - Ecology:
    • Ute Wittstock,
    • Niels Agerbirk,
    • Einar J. Stauber,
    • Carl Erik Olsen,
    • Michael Hippler,
    • Thomas Mitchell-Olds,
    • Jonathan Gershenzon,
    • and Heiko Vogel

    Successful herbivore attack due to metabolic diversion of a plant chemical defense

    PNAS 2004 101:4859-4864; published ahead of print March 29, 2004, doi:10.1073/pnas.0308007101

Evolution

  • Biological Sciences - Evolution:
    • Anthony G. Tsolaki,
    • Aaron E. Hirsh,
    • Kathryn DeRiemer,
    • Jose Antonio Enciso,
    • Melissa Z. Wong,
    • Margaret Hannan,
    • Yves-Olivier L. Goguet de la Salmoniere,
    • Kumiko Aman,
    • Midori Kato-Maeda,
    • and Peter M. Small

    From the Cover: Functional and evolutionary genomics of Mycobacterium tuberculosis : Insights from genomic deletions in 100 strains

    PNAS 2004 101:4865-4870; published ahead of print March 15, 2004, doi:10.1073/pnas.0305634101
    • See commentary article on page 4721 in issue 14 of volume 101
  • Biological Sciences - Evolution:
    • Aaron E. Hirsh,
    • Anthony G. Tsolaki,
    • Kathryn DeRiemer,
    • Marcus W. Feldman,
    • and Peter M. Small

    From the Cover: Stable association between strains of Mycobacterium tuberculosis and their human host populations

    PNAS 2004 101:4871-4876; published ahead of print March 23, 2004, doi:10.1073/pnas.0305627101
    • See commentary article on page 4721 in issue 14 of volume 101
  • Biological Sciences - Evolution:
    • Najmus S. Mahfooz,
    • Hua Li,
    • and Aleksandar Popadić

    From the Cover: Differential expression patterns of the hox gene are associated with differential growth of insect hind legs

    PNAS 2004 101:4877-4882; published ahead of print March 23, 2004, doi:10.1073/pnas.0401216101
  • Biological Sciences - Evolution:
    • Margarita Ramos,
    • Duncan J. Irschick,
    • and Terry E. Christenson

    Overcoming an evolutionary conflict: Removal of a reproductive organ greatly increases locomotor performance

    PNAS 2004 101:4883-4887; published ahead of print March 19, 2004, doi:10.1073/pnas.0400324101
  • Biological Sciences - Evolution:
    • Martin Hasselmann
    • and Martin Beye

    Signatures of selection among sex-determining alleles of the honey bee

    PNAS 2004 101:4888-4893; published ahead of print March 29, 2004, doi:10.1073/pnas.0307147101
  • Biological Sciences - Evolution:
    • Robert Belshaw,
    • Vini Pereira,
    • Aris Katzourakis,
    • Gillian Talbot,
    • Jan Pačes,
    • Austin Burt,
    • and Michael Tristem

    Long-term reinfection of the human genome by endogenous retroviruses

    PNAS 2004 101:4894-4899; published ahead of print March 25, 2004, doi:10.1073/pnas.0307800101
  • Biological Sciences - Evolution:
    • Henner Brinkmann,
    • Byrappa Venkatesh,
    • Sydney Brenner,
    • and Axel Meyer

    Nuclear protein-coding genes support lungfish and not the coelacanth as the closest living relatives of land vertebrates

    PNAS 2004 101:4900-4905; published ahead of print March 22, 2004, doi:10.1073/pnas.0400609101

Genetics

  • Biological Sciences - Genetics:
    • Vladimir I. Kashuba,
    • Jingfeng Li,
    • Fuli Wang,
    • Vera N. Senchenko,
    • Alexey Protopopov,
    • Alena Malyukova,
    • Alexey S. Kutsenko,
    • Elena Kadyrova,
    • Veronika I. Zabarovska,
    • Olga V. Muravenko,
    • Alexander V. Zelenin,
    • Lev L. Kisselev,
    • Igor Kuzmin,
    • John D. Minna,
    • Gösta Winberg,
    • Ingemar Ernberg,
    • Eleonora Braga,
    • Michael I. Lerman,
    • George Klein,
    • and Eugene R. Zabarovsky

    RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies

    PNAS 2004 101:4906-4911; published ahead of print March 29, 2004, doi:10.1073/pnas.0401238101
  • Biological Sciences - Genetics:
    • Sebastian Schuck,
    • Aki Manninen,
    • Masanori Honsho,
    • Joachim Füllekrug,
    • and Kai Simons

    Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference

    PNAS 2004 101:4912-4917; published ahead of print March 29, 2004, doi:10.1073/pnas.0401285101
  • Biological Sciences - Genetics:
    • Richard D. Palmiter

    Protection against zinc toxicity by metallothionein and zinc transporter 1

    PNAS 2004 101:4918-4923; published ahead of print March 23, 2004, doi:10.1073/pnas.0401022101
  • Biological Sciences - Genetics:
    • L. H. Castilla,
    • P. Perrat,
    • N. J. Martinez,
    • S. F. Landrette,
    • R. Keys,
    • S. Oikemus,
    • J. Flanegan,
    • S. Heilman,
    • L. Garrett,
    • A. Dutra,
    • S. Anderson,
    • G. A. Pihan,
    • L. Wolff,
    • and P. P. Liu

    Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia

    PNAS 2004 101:4924-4929; published ahead of print March 24, 2004, doi:10.1073/pnas.0400930101
  • Biological Sciences - Genetics:
    • Timothy E. Baroni,
    • Ting Wang,
    • Hua Qian,
    • Lawrence R. Dearth,
    • Lan N. Truong,