Table of Contents

Commentaries

Commentary:
- Dominik Wodarz
- and Martin A. Nowak
HIV therapy: Managing resistance
PNAS 2000 97:8193-8195
Commentary:
- Joseph J. LoTurco
Neural circuits in the 21st century: Synaptic networks of neurons and glia
PNAS 2000 97:8196-8197
- See companion article on page 8629 in issue 15 of volume 97
Commentary:
- David S. Pimentel
- and Peter H. Raven
Bt corn pollen impacts on nontarget Lepidoptera: Assessment of effects in nature
PNAS 2000 97:8198-8199
- See companion article on page 7700 in issue 14 of volume 97

Physical Sciences

Applied Mathematics

Select this article
Physical Sciences - Applied Mathematics:
- Weinan E Vanden Eijnden
- and Eric Vanden Eijnden
Generalized flows, intrinsic stochasticity, and turbulent transport
PNAS 2000 97:8200-8205
- Abstract
- Full Text (PDF)
Select this article
Physical Sciences - Applied Mathematics - Biological Sciences - Immunology:
- Vincent Detours
- and Alan S. Perelson
The paradox of alloreactivity and self MHC restriction: Quantitative analysis and statistics
PNAS 2000 97:8479-8483
- Abstract
- Full Text (PDF)

Applied Physical Sciences

Select this article
Physical Sciences - Applied Physical Sciences:
- Thomas A. Klar,
- Stefan Jakobs,
- Marcus Dyba,
- Alexander Egner,
- and Stefan W. Hell
Fluorescence microscopy with diffraction resolution barrier broken by stimulated emission
PNAS 2000 97:8206-8210
- See commentary article on page 8747 in issue 16 of volume 97
Select this article
Physical Sciences - Applied Physical Sciences:
- P. R. Garabedian
Compact stellarators with modular coils
PNAS 2000 97:8211-8215
- Abstract
- Full Text (PDF)

Chemistry

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Physical Sciences - Chemistry:
- Gábor Merényi,
- Johan Lind,
- Gidon Czapski,
- and Sara Goldstein
The decomposition of peroxynitrite does not yield nitroxyl anion and singlet oxygen
PNAS 2000 97:8216-8218; published online before print July 4, 2000
Select this article
Physical Sciences - Chemistry - Biological Sciences - Biophysics:
- M. C. Asplund,
- M. T. Zanni,
- and R. M. Hochstrasser
Two-dimensional infrared spectroscopy of peptides by phase-controlled femtosecond vibrational photon echoes
PNAS 2000 97:8219-8224; published online before print July 11, 2000
Select this article
Physical Sciences - Chemistry - Biological Sciences - Cell Biology:
- Cyril Papaseit,
- Nathalie Pochon,
- and James Tabony
Microtubule self-organization is gravity-dependent
PNAS 2000 97:8364-8368; published online before print July 4, 2000

Social Sciences

Psychology

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Biological Sciences - Psychology - Social Sciences - Psychology:
- Patrick Suppes
- and Bing Han
Brain-wave representation of words by superposition of a few sine waves
PNAS 2000 97:8738-8743; published online before print July 11, 2000

Biological Sciences

Anthropology

Select this article
Biological Sciences - Anthropology:
- Bing Su,
- Li Jin,
- Peter Underhill,
- Jeremy Martinson,
- Nilmani Saha,
- Stephen T. McGarvey,
- Mark D. Shriver,
- Jiayou Chu,
- Peter Oefner,
- Ranajit Chakraborty,
- and Ranjan Deka
Polynesian origins: Insights from the Y chromosome
PNAS 2000 97:8225-8228

Applied Biological Sciences

Select this article
Biological Sciences - Applied Biological Sciences:
- Jörg C. Heinrich
- and Maxwell J. Scott
A repressible female-specific lethal genetic system for making transgenic insect strains suitable for a sterile-release program
PNAS 2000 97:8229-8232; published online before print July 11, 2000

Biophysics

Select this article
Physical Sciences - Chemistry - Biological Sciences - Biophysics:
- M. C. Asplund,
- M. T. Zanni,
- and R. M. Hochstrasser
Two-dimensional infrared spectroscopy of peptides by phase-controlled femtosecond vibrational photon echoes
PNAS 2000 97:8219-8224; published online before print July 11, 2000
Select this article
Biological Sciences - Biophysics:
- Kevin C. Chen
- and Charles Nicholson
Changes in brain cell shape create residual extracellular space volume and explain tortuosity behavior during osmotic challenge
PNAS 2000 97:8306-8311; published online before print July 11, 2000
Select this article
Biological Sciences - Biophysics:
- Brandy S. Russell,
- Rory Melenkivitz,
- and Kara L. Bren
NMR investigation of ferricytochrome c unfolding: Detection of an equilibrium unfolding intermediate and residual structure in the denatured state
PNAS 2000 97:8312-8317; published online before print July 4, 2000
Select this article
Biological Sciences - Biophysics:
- R. A. G. D. Silva,
- Jan Kubelka,
- Petr Bour,
- Sean M. Decatur,
- and Timothy A. Keiderling
Site-specific conformational determination in thermal unfolding studies of helical peptides using vibrational circular dichroism with isotopic substitution
PNAS 2000 97:8318-8323; published online before print July 4, 2000
Select this article
Biological Sciences - Biophysics:
- David M. Huang
- and David Chandler
Temperature and length scale dependence of hydrophobic effects and their possible implications for protein folding
PNAS 2000 97:8324-8327; published online before print July 11, 2000
- See commentary article on page 733 in issue 3 of volume 104
Select this article
Biological Sciences - Biophysics:
- J. Halloy,
- B. A. Bernard,
- G. Loussouarn,
- and A. Goldbeter
Modeling the dynamics of human hair cycles by a follicular automaton
PNAS 2000 97:8328-8333
Select this article
Biological Sciences - Biophysics:
- Francisco López García,
- Ralph Zahn,
- Roland Riek,
- and Kurt Wüthrich
NMR structure of the bovine prion protein
PNAS 2000 97:8334-8339
Select this article
Biological Sciences - Biophysics:
- Luigi Calzolai,
- Dominikus A. Lysek,
- Peter Güntert,
- Christine von Schroetter,
- Roland Riek,
- Ralph Zahn,
- and Kurt Wüthrich
NMR structures of three single-residue variants of the human prion protein
PNAS 2000 97:8340-8345

Cell Biology

Select this article
Biological Sciences - Cell Biology:
- Takashi Shinohara,
- Kyle E. Orwig,
- Mary R. Avarbock,
- and Ralph L. Brinster
From the Cover: Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells
PNAS 2000 97:8346-8351
Select this article
Biological Sciences - Cell Biology:
- George R. Beck, Jr.,
- Brad Zerler,
- and Elizabeth Moran
Phosphate is a specific signal for induction of osteopontin gene expression
PNAS 2000 97:8352-8357; published online before print July 11, 2000
Select this article
Biological Sciences - Cell Biology:
- Etienne Labbé,
- Ainhoa Letamendia,
- and Liliana Attisano
Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-β and Wnt pathways
PNAS 2000 97:8358-8363; published online before print July 11, 2000
Select this article
Physical Sciences - Chemistry - Biological Sciences - Cell Biology:
- Cyril Papaseit,
- Nathalie Pochon,
- and James Tabony
Microtubule self-organization is gravity-dependent
PNAS 2000 97:8364-8368; published online before print July 4, 2000
Select this article
Biological Sciences - Cell Biology:
- Silvia Schnyder-Candrian,
- Lubor Borsig,
- René Moser,
- and Eric G. Berger
Localization of α1,3-fucosyltransferase VI in Weibel–Palade bodies of human endothelial cells
PNAS 2000 97:8369-8374
Select this article
Biological Sciences - Cell Biology:
- Sanna Heino,
- Sari Lusa,
- Pentti Somerharju,
- Christian Ehnholm,
- Vesa M. Olkkonen,
- and Elina Ikonen
Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface
PNAS 2000 97:8375-8380; published online before print July 11, 2000
Select this article
Biological Sciences - Cell Biology:
- Nico P. Dantuma,
- Stijn Heessen,
- Kristina Lindsten,
- Marianne Jellne,
- and Maria G. Masucci
Inhibition of proteasomal degradation by the Gly-Ala repeat of Epstein–Barr virus is influenced by the length of the repeat and the strength of the degradation signal
PNAS 2000 97:8381-8385; published online before print July 11, 2000

Developmental Biology

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Biological Sciences - Developmental Biology:
- Jun Peng,
- Liyong Zhang,
- Linsay Drysdale,
- and Guo-Hua Fong
The transcription factor EPAS-1/hypoxia-inducible factor 2α plays an important role in vascular remodeling
PNAS 2000 97:8386-8391; published online before print July 4, 2000

Evolution

Select this article
Biological Sciences - Evolution:
- Carl R. Woese
Interpreting the universal phylogenetic tree
PNAS 2000 97:8392-8396

Genetics

Select this article
Biological Sciences - Genetics:
- Florence Le Page,
- Arne Klungland,
- Deborah E. Barnes,
- Alain Sarasin,
- and Serge Boiteux
Transcription coupled repair of 8-oxoguanine in murine cells: The Ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences
PNAS 2000 97:8397-8402; published online before print July 11, 2000
Select this article
Biological Sciences - Genetics:
- Martijn E. T. Dollé,
- Wendy K. Snyder,
- Jan A. Gossen,
- Paul H. M. Lohman,
- and Jan Vijg
Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine
PNAS 2000 97:8403-8408
Select this article
Biological Sciences - Genetics:
- Neal S. Holter,
- Madhusmita Mitra,
- Amos Maritan,
- Marek Cieplak,
- Jayanth R. Banavar,
- and Nina V. Fedoroff
Fundamental patterns underlying gene expression profiles: Simplicity from complexity
PNAS 2000 97:8409-8414; published online before print July 11, 2000
Select this article
Biological Sciences - Genetics:
- Ingo H. Greger,
- Agustín Aranda,
- and Nick Proudfoot
Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae
PNAS 2000 97:8415-8420; published online before print July 11, 2000

FROM THE COVER

HIV therapy: Managing resistance

Neural circuits in the 21st century: Synaptic networks of neurons and glia

Bt corn pollen impacts on nontarget Lepidoptera: Assessment of effects in nature

Generalized flows, intrinsic stochasticity, and turbulent transport

The paradox of alloreactivity and self MHC restriction: Quantitative analysis and statistics

Fluorescence microscopy with diffraction resolution barrier broken by stimulated emission

Compact stellarators with modular coils

The decomposition of peroxynitrite does not yield nitroxyl anion and singlet oxygen

Two-dimensional infrared spectroscopy of peptides by phase-controlled femtosecond vibrational photon echoes

Microtubule self-organization is gravity-dependent

Brain-wave representation of words by superposition of a few sine waves

Polynesian origins: Insights from the Y chromosome

A repressible female-specific lethal genetic system for making transgenic insect strains suitable for a sterile-release program

Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

A deoxyribonucleotidase in mitochondria: Involvement in regulation of dNTP pools and possible link to genetic disease

Structure–activity analysis of buforin II, a histone H2A-derived antimicrobial peptide: The proline hinge is responsible for the cell-penetrating ability of buforin II

Biosynthesis of terpenoids: 4-Diphosphocytidyl-2-C-methyl-d-erythritol kinase from tomato

Crystal structure of the Holliday junction DNA in complex with a single RuvA tetramer

m5C RNA and m5C DNA methyl transferases use different cysteine residues as catalysts

Memory landscapes of single-enzyme molecules

From the Cover: Sensitive detection of DNA polymorphisms by the serial invasive signal amplification reaction

A cytotoxic ribonuclease which specifically cleaves four isoaccepting arginine tRNAs at their anticodon loops

Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids

Activation of polyamine catabolism in transgenic rats induces acute pancreatitis

A quantitative, high-throughput screen for protein stability

Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53

Two-dimensional infrared spectroscopy of peptides by phase-controlled femtosecond vibrational photon echoes

Changes in brain cell shape create residual extracellular space volume and explain tortuosity behavior during osmotic challenge

NMR investigation of ferricytochrome c unfolding: Detection of an equilibrium unfolding intermediate and residual structure in the denatured state

Site-specific conformational determination in thermal unfolding studies of helical peptides using vibrational circular dichroism with isotopic substitution

Temperature and length scale dependence of hydrophobic effects and their possible implications for protein folding

Modeling the dynamics of human hair cycles by a follicular automaton

NMR structure of the bovine prion protein

NMR structures of three single-residue variants of the human prion protein

From the Cover: Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells

Phosphate is a specific signal for induction of osteopontin gene expression

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-β and Wnt pathways

Microtubule self-organization is gravity-dependent

Localization of α1,3-fucosyltransferase VI in Weibel–Palade bodies of human endothelial cells

Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface

Inhibition of proteasomal degradation by the Gly-Ala repeat of Epstein–Barr virus is influenced by the length of the repeat and the strength of the degradation signal

The transcription factor EPAS-1/hypoxia-inducible factor 2α plays an important role in vascular remodeling

Interpreting the universal phylogenetic tree

Transcription coupled repair of 8-oxoguanine in murine cells: The Ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences

Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine

Fundamental patterns underlying gene expression profiles: Simplicity from complexity

Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae

m⁵C RNA and m⁵C DNA methyl transferases use different cysteine residues as catalysts