Table of Contents

• William S. Hlavacek,
• Carla Wofsy,
• and Alan S. Perelson

Dissociation of HIV-1 from follicular dendritic cells during HAART: Mathematical analysis

• Andrew J. Majda,
• Ilya Timofeyev,
• and Eric Vanden Eijnden

Models for stochastic climate prediction

• Johan Chu
• and Christoph Adami

A simple explanation for taxon abundance patterns

• Anja Ruebner,
• Zhiwei Yang,
• David Leung,
• and Ronald Breslow

A cyclodextrin dimer with a photocleavable linker as a possible carrier for the photosensitizer in photodynamic tumor therapy

• Yongsheng Liu,
• Matthew P. Patricelli,
• and Benjamin F. Cravatt

Activity-based protein profiling: The serine hydrolases

• Kui Gao
• and Leslie E. Orgel

Nucleic acid duplexes incorporating a dissociable covalent base pair

• Geoffrey L. Price

On the classification of binary shifts of finite commutant index

• Yongsheng Liu,
• Matthew P. Patricelli,
• and Benjamin F. Cravatt

Activity-based protein profiling: The serine hydrolases

• Katherine E. McAuley,
• Paul K. Fyfe,
• Justin P. Ridge,
• Neil W. Isaacs,
• Richard J. Cogdell,
• and Michael R. Jones

Structural details of an interaction between cardiolipin and an integral membrane protein

• Luc Jaeger,
• Martin C. Wright,
• and Gerald F. Joyce

A complex ligase ribozyme evolved in vitro from a group I ribozyme domain

• Alessandro Giuffrè,
• Gottfried Stubauer,
• Paolo Sarti,
• Maurizio Brunori,
• Walter G. Zumft,
• Gerhard Buse,
• and Tewfik Soulimane

The heme-copper oxidases of Thermus thermophilus catalyze the reduction of nitric oxide: Evolutionary implications

• Yi-Fen Lee,
• Chih-Rong Shyr,
• Tin Htwe Thin,
• Wen-Jye Lin,
• and Chawnshang Chang

Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: A unique signaling pathway in the steroid receptor superfamily

• Andrea T. Hadfield,
• Guy D. Diana,
• and Michael G. Rossmann

Analysis of three structurally related antiviral compounds in complex with human rhinovirus 16

• Elena Shpak,
• Joseph F. Leykam,
• and Marcia J. Kieliszewski

Synthetic genes for glycoprotein design and the elucidation of hydroxyproline-O-glycosylation codes

• Hao Zhu,
• Huawei Qiu,
• Hae-Won Patricia Yoon,
• Shuning Huang,
• and H. Franklin Bunn

Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells

• Rhonda A. Torres
• and Thomas C. Bruice

Theoretical investigation of the [1,2]-sigmatropic hydrogen migration in the mechanism of oxidation of 2-aminobenzoyl-CoA by 2-aminobenzoyl-CoA monooxygenase/reductase

• Yunde Zhao,
• Philip E. Brandish,
• David P. Ballou,
• and Michael A. Marletta

A molecular basis for nitric oxide sensing by soluble guanylate cyclase

• S. Mariana Babor
• and Deborah Fass

Crystal structure of the Sec18p N-terminal domain

• Valery V. Peremyslov,
• Yuka Hagiwara,
• and Valerian V. Dolja

HSP70 homolog functions in cell-to-cell movement of a plant virus

• Dietrich Ober
• and Thomas Hartmann

Homospermidine synthase, the first pathway-specific enzyme of pyrrolizidine alkaloid biosynthesis, evolved from deoxyhypusine synthase

• Zvi Kelman,
• Joon-Kyu Lee,
• and Jerard Hurwitz

The single minichromosome maintenance protein of Methanobacterium thermoautotrophicum ΔH contains DNA helicase activity

• Dalai Yan,
• Ho S. Cho,
• Curtis A. Hastings,
• Michele M. Igo,
• Seok-Yong Lee,
• Jeffrey G. Pelton,
• Valley Stewart,
• David E. Wemmer,
• and Sydney Kustu

Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators

• A. Ahmed,
• D. Martín,
• A. G. O. Manetti,
• S.-J. Han,
• W.-J. Lee,
• K. D. Mathiopoulos,
• H.-M. Müller,
• F. C. Kafatos,
• A. Raikhel,
• and P. T. Brey

Genomic structure and ecdysone regulation of the prophenoloxidase 1 gene in the malaria vector Anopheles gambiae

• Motonari Uesugi
• and Gregory L. Verdine

The α-helical FXXΦΦ motif in p53: TAF interaction and discrimination by MDM2

• Jun Zhu,
• Maurizio Gianni,
• Eliezer Kopf,
• Nicole Honoré,
• Mounira Chelbi-Alix,
• Marcel Koken,
• Frédérique Quignon,
• Cécile Rochette-Egly,
• and Hugues de Thé

Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor α (RARα) and oncogenic RARα fusion proteins

• Matthew S. Fitzgerald,
• Karel Riha,
• Feng Gao,
• Shuxin Ren,
• Thomas D. McKnight,
• and Dorothy E. Shippen

Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

• Zonglin Hu,
• Amit Mukherjee,
• Sebastien Pichoff,
• and Joe Lutkenhaus

The MinC component of the division site selection system in Escherichia coli interacts with FtsZ to prevent polymerization

• Sylvain Arnould,
• Masayuki Takahashi,
• and Jean-Michel Camadro

Acylation stabilizes a protease-resistant conformation of protoporphyrinogen oxidase, the molecular target of diphenyl ether-type herbicides

• Sophie Deltour,
• Cateline Guerardel,
• and Dominique Leprince

Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: The case of HIC-1 and γFBP-B

• Kui Gao
• and Leslie E. Orgel

Nucleic acid duplexes incorporating a dissociable covalent base pair

• Kazumasa Miyawaki,
• Yuichiro Yamada,
• Hideki Yano,
• Hitoshi Niwa,
• Nobuhiro Ban,
• Yu Ihara,
• Akira Kubota,
• Shinpei Fujimoto,
• Mariko Kajikawa,
• Akira Kuroe,
• Kinsuke Tsuda,
• Hiroyuki Hashimoto,
• Tokuyuki Yamashita,
• Takahito Jomori,
• Fumi Tashiro,
• Jun-ichi Miyazaki,
• and Yutaka Seino

Glucose intolerance caused by a defect in the entero-insular axis: A study in gastric inhibitory polypeptide receptor knockout mice

• Nathan Hillson,
• José Nelson Onuchic,
• and Angel E. García

Pressure-induced protein-folding/unfolding kinetics

• Tomas Ternström,
• Ugo Mayor,
• Mikael Akke,
• and Mikael Oliveberg

From snapshot to movie: φ analysis of protein folding transition states taken one step further

• Steven J. Lahr,
• Anne Broadwater,
• Charles W. Carter, Jr.,
• Martha L. Collier,
• Lucinda Hensley,
• Jennifer C. Waldner,
• Gary J. Pielak,
• and Marshall Hall Edgell

Patterned library analysis: A method for the quantitative assessment of hypotheses concerning the determinants of protein structure

• James S. Hardwick,
• Finny G. Kuruvilla,
• Jeffrey K. Tong,
• Alykhan F. Shamji,
• and Stuart L. Schreiber

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

• David C. S. Huang,
• Michael Hahne,
• Michael Schroeter,
• Karl Frei,
• Adriano Fontana,
• Andreas Villunger,
• Kim Newton,
• Juerg Tschopp,
• and Andreas Strasser

Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x_L

• Haolin Chen
• and Barry R. Zirkin

Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging

• Sandra McNeil,
• Congmei Zeng,
• Kimberly S. Harrington,
• Scott Hiebert,
• Jane B. Lian,
• Janet L. Stein,
• André J. van Wijnen,
• and Gary S. Stein

The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFα2 transcription factor

• Michael Streit,
• Lucia Riccardi,
• Paula Velasco,
• Lawrence F. Brown,
• Thomas Hawighorst,
• Paul Bornstein,
• and Michael Detmar

Thrombospondin-2: A potent endogenous inhibitor of tumor growth and angiogenesis

• Susan M. Bailey,
• Julianne Meyne,
• David J. Chen,
• Akihiro Kurimasa,
• Gloria C. Li,
• Bruce E. Lehnert,
• and Edwin H. Goodwin

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

• Natalie Erdmann,
• Tamara Petroff,
• and Barbara E. Funnell

Intracellular localization of P1 ParB protein depends on ParA and parS

• Gen Inoue,
• Bentley Cheatham,
• and C. Ronald Kahn

Development of an in vitro reconstitution assay for glucose transporter 4 translocation

• Carlos M. Luque,