Synthesis of Acid Mucopolysaccharides by Glial Tumor Cells in Tissue Culture*
- Albert Dorfman† and
- Pei-Lee Ho
- DEPARTMENT OF PEDIATRICS, THE JOSEPH P. KENNEDY, JR. MENTAL RETARDATION RESEARCH CENTER
- DEPARTMENT OF BIOCHEMISTRY, THE JOSEPH P. KENNEDY, JR. MENTAL RETARDATION RESEARCH CENTER
- THE PRITZKER SCHOOL OF MEDICINE, UNIVERSITY OF CHICAGO
Abstract
A clonal strain of rat glial tumor cells was shown to produce the acid mucopolysaccharides, hyaluronic acid, chondroitin 4-SO4, and heparan sulfate in tissue culture. The mucopolysaccharides were isolated both from the growth medium and the cells.
Footnotes
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† Requests for reprints may be addressed to Dr. Dorfman, Departments of Pediatrics and Biochemistry, University of Chicago,
Chicago, Ill. 60637.
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* These studies were supported by USPHS grants AM-05996 and 1-PO1 HD-04583.
