AN ATP-DEPENDENT DEOXYRIBONUCLEASE FROM Escherichia coli WITH A POSSIBLE ROLE IN GENETIC RECOMBINATION

  1. M. Oishi
  1. DEPARTMENT OF GENETICS, THE PUBLIC HEALTH RESEARCH INSTITUTE OF THE CITY OF NEW YORK, INC., NEW YORK

Abstract

A DNase which requires ATP for its function was purified from E. coli and some of the characteristics of the purified enzyme were studied. This enzyme activity could not be detected in certain (recB and recC) recombination deficient mutant strains. The possible role of the enzyme in genetic recombination is discussed.

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