Lithium may slow progression of amyotrophic lateral sclerosis, but further study is needed
- *Duke University ALS Clinic, 932 Morreene Road, Durham, NC 27705;
- ‡The ALS Center at Johns Hopkins, 600 North Wolfe Street Baltimore, MD 21287; and
- §MDA/ALS Center of Hope, Drexel University College of Medicine, P.O. Box 40777, Philadelphia, PA 19107
To the Editor: In the February 12, 2008 edition of PNAS, Fornai et al. (1) suggest that lithium slows human ALS progression. We have several questions about their study.
Was this trial registered before enrollment, as required by the International Committee of Medical Journal Editors (2)? If not, why? How were …
†To whom correspondence should be addressed. E-mail: bedla001{at}mc.duke.edu
