Cover illustration

April 4, 2006; 103 (14)
Cover image expansion

Cover image: Serotonin axons projecting to the hippocampus in mouse brain, visualized immunocytochemically as gold thread-like structures. Oxidative stress in neurons was modeled by using photogenerated radicals in a membrane-encapsulated microtubule system. Factors accelerating or attenuating axon degeneration caused by free radicals were investigated with this model. See the article by Counterman et al. on pages 5262–5266. Image courtesy of Beth A. Luellen (Pennsylvania State University, University Park).