A new model for vitamin K-dependent carboxylation: The catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine

Rishavy et al. 10.1073/pnas.0404989101.

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Fig. 4. Western analysis of carboxylase mutants. Solubilized microsomes from insect cells infected with baculoviruses containing mutant carboxylases substituted in Cys-99 or Cys-450 (A) or in the remaining Cys residues (B) were analyzed as described in the text.

This Article

  1. Published online before print September 13, 2004, doi: 10.1073/pnas.0404989101 PNAS September 21, 2004 vol. 101 no. 38 13732-13737
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