Commentaries

  • Commentary:
    • George P. Chrousos

    Is 11β-hydroxysteroid dehydrogenase type 1 a good therapeutic target for blockade of glucocorticoid actions?

    PNAS 2004 101:6329-6330; published online before print April 19, 2004, doi:10.1073/pnas.0401671101
    • See companion article on page 6734 in issue 17 of volume 101
  • Commentary:
    • Sandip Niyogi
    • and Robert C. Haddon

    Behavior of fluids in nanoscopic space

    PNAS 2004 101:6331-6332; published online before print April 19, 2004, doi:10.1073/pnas.0401508101
    • See companion article on page 4009 in issue 12 of volume 101
  • Commentary:
    • Hugo D. Critchley

    The human cortex responds to an interoceptive challenge

    PNAS 2004 101:6333-6334; published online before print April 19, 2004, doi:10.1073/pnas.0401510101
    • See companion article on page 6217 in issue 16 of volume 101

Physical Sciences

Engineering

  • Physical Sciences - Engineering:
    • M. A. Haque
    • and M. T. A. Saif

    Deformation mechanisms in free-standing nanoscale thin films: A quantitative in situ transmission electron microscope study

    PNAS 2004 101:6335-6340; published online before print April 14, 2004, doi:10.1073/pnas.0400066101

Geophysics

  • Physical Sciences - Geophysics:
    • Ryan C. Bay,
    • Nathan Bramall,
    • and P. Buford Price

    Bipolar correlation of volcanism with millennial climate change

    PNAS 2004 101:6341-6345; published online before print April 19, 2004, doi:10.1073/pnas.0400323101
  • Physical Sciences - Geophysics:
    • Renyi Zhang,
    • Wenfang Lei,
    • Xuexi Tie,
    • and Peter Hess

    Industrial emissions cause extreme urban ozone diurnal variability

    PNAS 2004 101:6346-6350; published online before print April 14, 2004, doi:10.1073/pnas.0401484101

Social Sciences

Anthropology

  • Social Sciences - Anthropology:
    • Dani Nadel,
    • Ehud Weiss,
    • Orit Simchoni,
    • Alexander Tsatskin,
    • Avinoam Danin,
    • and Mordechai Kislev

    From the Cover: Stone Age hut in Israel yields world's oldest evidence of bedding

    PNAS 2004 101:6821-6826; published online before print April 16, 2004, doi:10.1073/pnas.0308557101
    • See commentary article on page 7207 in issue 19 of volume 101

Psychology

  • Social Sciences - Psychology:
    • Hans C. Lou,
    • Bruce Luber,
    • Michael Crupain,
    • Julian P. Keenan,
    • Markus Nowak,
    • Troels W. Kjaer,
    • Harold A. Sackeim,
    • and Sarah H. Lisanby

    Parietal cortex and representation of the mental Self

    PNAS 2004 101:6827-6832; published online before print April 19, 2004, doi:10.1073/pnas.0400049101

Biological Sciences

Agricultural Sciences

  • Biological Sciences - Agricultural Sciences:
    • K. Schmidt-Rohr,
    • J.-D. Mao,
    • and D. C. Olk

    Nitrogen-bonded aromatics in soil organic matter and their implications for a yield decline in intensive rice cropping

    PNAS 2004 101:6351-6354; published online before print April 19, 2004, doi:10.1073/pnas.0401349101

Applied Biological Sciences

  • Biological Sciences - Applied Biological Sciences:
    • Subhayu Basu,
    • Rishabh Mehreja,
    • Stephan Thiberge,
    • Ming-Tang Chen,
    • and Ron Weiss

    Spatiotemporal control of gene expression with pulse-generating networks

    PNAS 2004 101:6355-6360; published online before print April 19, 2004, doi:10.1073/pnas.0307571101
  • Biological Sciences - Applied Biological Sciences:
    • Kazuhiro Saeki,
    • Kazuya Matsumoto,
    • Mikio Kinoshita,
    • Iwane Suzuki,
    • Yasushi Tasaka,
    • Koichiro Kano,
    • Yoshitomo Taguchi,
    • Koji Mikami,
    • Masumi Hirabayashi,
    • Naomi Kashiwazaki,
    • Yoshihiko Hosoi,
    • Norio Murata,
    • and Akira Iritani

    From the Cover: Functional expression of a Δ12 fatty acid desaturase gene from spinach in transgenic pigs

    PNAS 2004 101:6361-6366; published online before print April 5, 2004, doi:10.1073/pnas.0308111101
    • See commentary article on page 7211 in issue 19 of volume 101

Biochemistry

  • Biological Sciences - Biochemistry:
    • D. Borden Lacy,
    • Darran J. Wigelsworth,
    • Heather M. Scobie,
    • John A. T. Young,
    • and R. John Collier

    Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: An anthrax toxin receptor

    PNAS 2004 101:6367-6372; published online before print April 12, 2004, doi:10.1073/pnas.0401506101
  • Biological Sciences - Biochemistry:
    • Chon-Hwa Tsai-Morris,
    • Yi Sheng,
    • Eric Lee,
    • Ke-Jian Lei,
    • and Maria L. Dufau

    Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis

    PNAS 2004 101:6373-6378; published online before print April 19, 2004, doi:10.1073/pnas.0401855101
  • Biological Sciences - Biochemistry:
    • Hozumi Motohashi,
    • Fumiki Katsuoka,
    • James Douglas Engel,
    • and Masayuki Yamamoto

    Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1–Nrf2 regulatory pathway

    PNAS 2004 101:6379-6384; published online before print April 15, 2004, doi:10.1073/pnas.0305902101
  • Biological Sciences - Biochemistry:
    • Ruanbao Zhou
    • and Lee Kroos

    BofA protein inhibits intramembrane proteolysis of pro-σK in an intercompartmental signaling pathway during Bacillus subtilis sporulation

    PNAS 2004 101:6385-6390; published online before print April 15, 2004, doi:10.1073/pnas.0307709101
  • Biological Sciences - Biochemistry:
    • Samuel E. Bennett,
    • Cheng-Yao Chen,
    • and Dale W. Mosbaugh

    Escherichia coli nucleoside diphosphate kinase does not act as a uracil-processing DNA repair nuclease

    PNAS 2004 101:6391-6396; published online before print April 19, 2004, doi:10.1073/pnas.0401031101
  • Biological Sciences - Biochemistry:
    • Alessandra Romanelli,
    • Alexander Shekhtman,
    • David Cowburn,
    • and Tom W. Muir

    Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein–intein junction

    PNAS 2004 101:6397-6402; published online before print April 15, 2004, doi:10.1073/pnas.0306616101
  • Biological Sciences - Biochemistry:
    • Ellen A. A. Nollen,
    • Susana M. Garcia,
    • Gijs van Haaften,
    • Soojin Kim,
    • Alejandro Chavez,
    • Richard I. Morimoto,
    • and Ronald H. A. Plasterk

    From the Cover: Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

    PNAS 2004 101:6403-6408; published online before print April 14, 2004, doi:10.1073/pnas.0307697101
  • Biological Sciences - Biochemistry:
    • Pawel Dobrzyn,
    • Agnieszka Dobrzyn,
    • Makoto Miyazaki,
    • Paul Cohen,
    • Esra Asilmaz,
    • D. Grahame Hardie,
    • Jeffrey M. Friedman,
    • and James M. Ntambi

    Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver

    PNAS 2004 101:6409-6414; published online before print April 19, 2004, doi:10.1073/pnas.0401627101
  • Biological Sciences - Biochemistry:
    • Min Xu,
    • Douglas K. Struck,
    • John Deaton,
    • Ing-Nang Wang,
    • and Ry Young

    A signal-arrest-release sequence mediates export and control of the phage P1 endolysin

    PNAS 2004 101:6415-6420; published online before print April 16, 2004, doi:10.1073/pnas.0400957101
  • Biological Sciences - Biochemistry:
    • Jeffrey E. Barrick,
    • Keith A. Corbino,
    • Wade C. Winkler,
    • Ali Nahvi,
    • Maumita Mandal,
    • Jennifer Collins,
    • Mark Lee,
    • Adam Roth,
    • Narasimhan Sudarsan,
    • Inbal Jona,
    • J. Kenneth Wickiser,
    • and Ronald R. Breaker

    New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control

    PNAS 2004 101:6421-6426; published online before print April 19, 2004, doi:10.1073/pnas.0308014101
  • Biological Sciences - Biochemistry:
    • Yoshinori Hiraoka,
    • Tohru Yamada,
    • Masatoshi Goto,
    • Tapas K. Das Gupta,
    • and Ananda M. Chakrabarty

    Modulation of mammalian cell growth and death by prokaryotic and eukaryotic cytochrome c

    PNAS 2004 101:6427-6432; published online before print April 13, 2004, doi:10.1073/pnas.0401631101

Biophysics

  • Biological Sciences - Biophysics:
    • Brian J. Bennion
    • and Valerie Daggett

    Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: A chemical chaperone at atomic resolution

    PNAS 2004 101:6433-6438; published online before print April 19, 2004, doi:10.1073/pnas.0308633101
  • Biological Sciences - Biophysics:
    • Marie-Noëlle Dessinges,
    • Timothée Lionnet,
    • Xu Guang Xi,
    • David Bensimon,
    • and Vincent Croquette

    Single-molecule assay reveals strand switching and enhanced processivity of UvrD

    PNAS 2004 101:6439-6444; published online before print April 12, 2004, doi:10.1073/pnas.0306713101
  • Biological Sciences - Biophysics:
    • Nizar N. Batada,
    • Larry A. Shepp,
    • and David O. Siegmund

    Stochastic model of protein–protein interaction: Why signaling proteins need to be colocalized

    PNAS 2004 101:6445-6449; published online before print April 19, 2004, doi:10.1073/pnas.0401314101
  • Biological Sciences - Biophysics:
    • Per Jemth,
    • Stefano Gianni,
    • Ryan Day,
    • Bin Li,
    • Christopher M. Johnson,
    • Valerie Daggett,
    • and Alan R. Fersht

    Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation

    PNAS 2004 101:6450-6455; published online before print April 19, 2004, doi:10.1073/pnas.0401732101
  • Biological Sciences - Biophysics:
    • Young Min Rhee,
    • Eric J. Sorin,
    • Guha Jayachandran,
    • Erik Lindahl,
    • and Vijay S. Pande

    Simulations of the role of water in the protein-folding mechanism

    PNAS 2004 101:6456-6461; published online before print April 16, 2004, doi:10.1073/pnas.0307898101
  • Biological Sciences - Biophysics:
    • Matthew P. Gordon,
    • Taekjip Ha,
    • and Paul R. Selvin

    Single-molecule high-resolution imaging with photobleaching

    PNAS 2004 101:6462-6465; published online before print April 19, 2004, doi:10.1073/pnas.0401638101
  • Biological Sciences - Biophysics:
    • L. Bongini,
    • D. Fanelli,
    • F. Piazza,
    • P. De Los Rios,
    • S. Sandin,
    • and U. Skoglund

    Freezing immunoglobulins to see them move

    PNAS 2004 101:6466-6471; published online before print April 13, 2004, doi:10.1073/pnas.0400119101

Cell Biology

  • Biological Sciences - Cell Biology:
    • Sylvia N. Schreiber,
    • Roger Emter,
    • M. Benjamin Hock,
    • Darko Knutti,
    • Jessica Cardenas,
    • Michael Podvinec,
    • Edward J. Oakeley,
    • and Anastasia Kralli

    The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis

    PNAS 2004 101:6472-6477; published online before print April 15, 2004, doi:10.1073/pnas.0308686101
  • Biological Sciences - Cell Biology:
    • Ricardo D. Coletta,
    • Kimberly Christensen,
    • Kelly J. Reichenberger,
    • Justin Lamb,
    • Damian Micomonaco,
    • Lili Huang,
    • Douglas M. Wolf,
    • Carsten Müller-Tidow,
    • Todd R. Golub,
    • Kiyoshi Kawakami,
    • and Heide L. Ford

    The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1

    PNAS 2004 101:6478-6483; published online before print April 26, 2004, doi:10.1073/pnas.0401139101
  • Biological Sciences - Cell Biology:
    • Shiaw-Yih Lin,
    • Kaiyi Li,
    • Grant S. Stewart,
    • and Stephen J. Elledge

    Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation

    PNAS 2004 101:6484-6489; published online before print April 19, 2004, doi:10.1073/pnas.0401847101
  • Biological Sciences - Cell Biology:
    • NanLing Gong,
    • Heming Wei,
    • Sanaul Haq Chowdhury,
    • and Subroto Chatterjee

    Lactosylceramide recruits PKCα/ε and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells

    PNAS 2004 101:6490-6495; published online before print April 14, 2004, doi:10.1073/pnas.0308684101

Developmental Biology

  • Biological Sciences - Developmental Biology:
    • Lin Liu,
    • Sonia Franco,
    • Barbara Spyropoulos,
    • Peter B. Moens,
    • Maria A. Blasco,
    • and David L. Keefe

    Irregular telomeres impair meiotic synapsis and recombination in mice

    PNAS 2004 101:6496-6501; published online before print April 14, 2004, doi:10.1073/pnas.0400755101
  • Biological Sciences - Developmental Biology:
    • Haruhiko Akiyama,
    • Marie-Christine Chaboissier,
    • Richard R. Behringer,
    • David H. Rowitch,
    • Andreas Schedl,
    • Jonathan A. Epstein,
    • and Benoit de Crombrugghe

    Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa

    PNAS 2004 101:6502-6507; published online before print April 19, 2004, doi:10.1073/pnas.0401711101
  • Biological Sciences - Developmental Biology:
    • Yuval Kluger,
    • David P. Tuck,
    • Joseph T. Chang,
    • Yasuhiro Nakayama,
    • Ranjana Poddar,
    • Naohiko Kohya,
    • Zheng Lian,
    • Abdelhakim Ben Nasr,
    • H. Ruth Halaban,
    • Diane S. Krause,
    • Xueqing Zhang,
    • Peter E. Newburger,
    • and Sherman M. Weissman

    Lineage specificity of gene expression patterns

    PNAS 2004 101:6508-6513; published online before print April 19, 2004, doi:10.1073/pnas.0401136101

Evolution

  • Biological Sciences - Evolution:
    • Luciano B. Beheregaray,
    • James P. Gibbs,
    • Nathan Havill,
    • Thomas H. Fritts,
    • Jeffrey R. Powell,
    • and Adalgisa Caccone

    Giant tortoises are not so slow: Rapid diversification and biogeographic consensus in the Galápagos

    PNAS 2004 101:6514-6519; published online before print April 14, 2004, doi:10.1073/pnas.0400393101
  • Biological Sciences - Evolution:
    • Emily A. Dyson
    • and Gregory D. D. Hurst

    Persistence of an extreme sex-ratio bias in a natural population

    PNAS 2004 101:6520-6523; published online before print April 15, 2004, doi:10.1073/pnas.0304068101
  • Biological Sciences - Evolution:
    • Ho-Sung Yoon
    • and David A. Baum

    Transgenic study of parallelism in plant morphological evolution

    PNAS 2004 101:6524-6529; published online before print April 19, 2004, doi:10.1073/pnas.0401824101
  • Biological Sciences - Evolution:
    • Patricia L. M. Lee
    • and Graeme C. Hays

    Polyandry in a marine turtle: Females make the best of a bad job

    PNAS 2004 101:6530-6535; published online before print April 19, 2004, doi:10.1073/pnas.0307982101
  • Biological Sciences - Evolution:
    • Kevin J. Peterson,
    • Jessica B. Lyons,
    • Kristin S. Nowak,
    • Carter M. Takacs,
    • Matthew J. Wargo,
    • and Mark A. McPeek

    Estimating metazoan divergence times with a molecular clock

    PNAS 2004 101:6536-6541; published online before print April 14, 2004, doi:10.1073/pnas.0401670101
  • Biological Sciences - Evolution: