On BC1 RNA and the fragile X mental retardation protein
- Department of Experimental Medicine and Biochemical Sciences, Faculty of Medicine, University of Rome “Tor Vergata,” 00133 Rome, Italy; and Department of Molecular and Developmental Genetics/VIB11, Faculty of Medicine, Catholic University of Leuven Medical School, Campus Gasthuisberg, 3000 Leuven, Belgium
To the editor: Iacoangeli et al. (1) set out to reexamine our model that FMRP and the noncoding RNA BC1 act together to bind to mRNAs (2). Basing conclusions entirely on an inability to find this specific interaction, the authors suggest that FMRP and BC1 operate independently. Repeated statements suggesting experimental procedures are “replicating” …
*E-mail: claudia.bagni{at}med.kuleuven.be or claudia.bagni{at}uniroma2.it
