Structural basis for ligand promiscuity in cytochrome P450 3A4

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Fig. 1.
Fig. 1.

Chemical structures of ketoconazole (A) and erythromycin (B).


This Article

  1. PNAS September 12, 2006 vol. 103 no. 37 13682-13687