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Published online on April 23, 2008, 10.1073/pnas.0802669105
PNAS | April 29, 2008 | vol. 105 | no. 17 | E20


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LETTERS
Acetylcholinesterase inhibition and Gulf War illnesses: Conclusions are not supported by independent reviews of the same evidence

Dan Blazer*, Gregory C. Gray{dagger}, Matthew Hotopf{ddagger}, Gary Macfarlane§, Malcolm Sim, Tyler C. Smith||, and Simon Wessely**,{dagger}{dagger}

*Gibbons Professor of Psychiatry, Duke University Medical Center, Durham, NC 27710; {dagger}Center for Emerging Infectious Diseases and Department of Epidemiology and International Programs, University of Iowa College of Public Health, Iowa City, IA 52242; {ddagger}Department of Psychological Medicine, Institute of Psychiatry, King's College London, London SE5 9RJ, United Kingdom; §Epidemiology Group, Department of Public Health, University of Aberdeen, Aberdeen AB25 2ZD, United Kingdom; Centre for Occupational and Environmental Health, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne VIC 3004, Australia; ||Department of Defense Center for Deployment Health Research Naval Health Research Center, San Diego, CA 92186; and **Department of Psychological Medicine, King's Centre for Military Health Research, King's College London, London SE5 9RJ, United Kingdom

To the Editor: Golomb (1) concludes that there is strong evidence that exposure to acetylcholinesterase inhibitors [e.g., nerve agents, pyridostigmine bromide (PB), and pesticides] caused illness in 1991 Gulf War veterans (GWVs). We neither agree with her interpretation of the literature, including our own work, nor her conclusions, and believe she has neglected research that does not support her views.

The reported increase in extra cases of . . . [Full Text of this Article]

{dagger}{dagger}To whom correspondence should be addressed. E-mail: s.wessely@iop.kcl.ac.uk


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