Workshop on Schizophrenia

  1. Samuel H. Barondesa,
  2. Bruce M. Albertsb,
  3. Nancy C. Andreasenc,
  4. Cornelia Bargmannd,
  5. Francine Benese,
  6. Patricia Goldman-Rakicf,
  7. Irving Gottesmang,
  8. Stephen F. Heinemannh,
  9. Edward G. Jonesi,
  10. Marc Kirschnerj,
  11. David Lewisk,
  12. Martin Raffl,
  13. Allen Rosesm,
  14. John Rubensteinn,
  15. Solomon Snydero,
  16. Stanley J. Watsonp,
  17. Daniel R. Weinbergerq, and
  18. Robert H. Yolkenr
  1. aDepartment of Psychiatry, Center for Neurobiology and Psychiatry, University of California, San Francisco, CA 94143-0984; bNational Academy of Sciences, Washington, DC 20418; cThe University of Iowa, MHCRC, 2911 JPP, 200 Hawkins Drive, Iowa City, IA 52242-1553; dDepartment of Anatomy, University of California, San Francisco, CA 94143; eMailman Research Center, McLean Hospital, Belmont, MA 02178; fSection on Neurobiology, Yale University School of Medicine, New Haven, CT 06510; gDepartment of Psychology, University of Virginia, Charlottesville, VA 22903; hThe Salk Institute, P.O. Box 85800, San Diego, CA 92186; iDepartment of Anatomy and Neurobiology, College of Medicine, University of California, Irvine, CA 92717; jDepartment of Cell Biology, Harvard Medical School, Boston, MA 02115; kCenter for the Neuroscience of Mental Disorders, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2593; lLaboratory of Molecular Cell Biology, Department of Biology, Medawar Building, University College, London Gower Street, London WC1E 6BT, United Kingdom; mDivision of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC 27710; nDepartment of Psychiatry, University of California, San Francisco, CA 94143; oDepartment of Neuroscience, Johns Hopkins University, Baltimore, MD 21205; pMental Health Research Institute, University of Michigan, Ann Arbor, MI 48109-0720; qNational Institute of Mental Health, St. Elizabeth’s Neuroscience Center, Washington, DC 20032; and rDepartment of Pediatrics and Infectious Diseases, Johns Hopkins Medical School, Baltimore, MD 21205

Abstract

On November 29–30, 1995, the National Academy of Sciences and the Institute of Medicine brought together experts in schizophrenia and specialists in other areas of the biological sciences in a workshop aimed at promoting the application of the latest biological information to this clinical problem. The workshop paid particular attention to evidence of pathology in the brains of people with schizophrenia, and to the possibility that this reflects an abnormality in brain development that eventually leads to the appearance of symptoms. The participants were impressed with the complexity of the problem, and felt that multiple approaches would be required to understand this disease. They recommended that a major focus should be on the search for predisposing genes, but that there should be parallel research in many other areas.

Footnotes

  • Other participants of the workshop: W. Maxwell Cowan, Howard Hughes Medical Institute, Chevy Chase, MD 20815-6789; Rex William Cowdry, National Institute of Mental Health, Rockville, MD 20857; Zach Hall, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892; E. Fuller Torrey, National Institute of Mental Health, St. Elizabeth’s Neuroscience Center, Washington, DC 20032; Harold M. Varmus, National Institutes of Health, Bethesda, MD 20892.

  • To whom reprint requests should be addressed: Paul Gilman, Executive Director, Commission on Life Sciences, National Research Council, 2101 Constitution Avenue NW, Washington, DC 20418.

« Previous | Next Article »Table of Contents